Cost effectiveness of community leg ulcer clinics: randomised controlled trial [PDF]
Objectives: To establish the relative cost effectiveness of community leg ulcer clinics that use four layer compression bandaging versus usual care provided by district nurses.
Brereton, L.M.L. +6 more
core +2 more sources
Clinical effectiveness and cost-effectiveness of foam sclerotherapy, endovenous laser ablation and surgery for varicose veins: results from the Comparison of LAser, Surgery and foam Sclerotherapy (CLASS) randomised controlled trial. [PDF]
BACKGROUND: Foam sclerotherapy (foam) and endovenous laser ablation (EVLA) have emerged as alternative treatments to surgery for patients with varicose veins, but uncertainty exists regarding their effectiveness in the medium to longer term ...
+97 more
core +4 more sources
Towards an individualized management strategy for patients with chronic venous disease: Results of a Delphi consensus [PDF]
Objective: To obtain consensus on management criteria for symptomatic patients with chronic venous disease (CVD; C2–C6) and superficial venous reflux.
Bos, R.R. (Renate) van den +4 more
core +1 more source
Topical agents or dressings for pain in venous leg ulcers. [PDF]
Venous leg ulcers affect up to 1% of people at some time in their lives and are often painful. The main treatments are compression bandages and dressings.
Briggs, M +2 more
core +3 more sources
A randomized trial of early endovenous ablation in venous ulceration [PDF]
BACKGROUND Venous disease is the most common cause of leg ulceration. Although compression therapy improves venous ulcer healing, it does not treat the underlying causes of venous hypertension.
Bradbury, A +12 more
core +5 more sources
Clinical usage of honey as a wound dressing: An update [PDF]
Honey is an ancient treatment that is increasingly earning its place in modern wound care. Evidence suggests it compares with other dressings in terms of its antibacterial properties, ease of use and ability to promote a moist ...
Molan, Peter C.
core +2 more sources
Targeting Histamine H4 Receptor in the Rostral Ventromedial Medulla to Relieve Hypertension
H4R and its downstream TRPV1 channel mediate the excitatory effect of TMN histaminergic afferent inputs on GABAergic sympathoinhibitory neurons in RVMM. Intranasal delivery of selective H4R agonist VUF 8430 suppresses renal sympathetic outflow and elicits sustained depressor and bradycardia responses in SHRs and CUMS‐induced hypertensive rats ...
Ying Shi +18 more
wiley +1 more source
PIEZO Force Sensing in Vascular Biology: An Explosion of New Knowledge, Concepts and Opportunity
Knowledge of the remarkable mechanical force sensing and electrically transducing PIEZO1 and PIEZO2 channels is discussed across vascular biology and its cell types from the embryonic to adult stages in health, disease and old age. How the channels work, relate to other factors and signal for tissue responses to mechanical forces is debated.
David J Beech
wiley +1 more source
Introduction Chronic venous disease (CVD) constitutes a frequently underdiagnosed pathological condition that progressively diminishes patients’ quality of life and imposes an escalating strain on healthcare resources.
Francesk Mulita +11 more
doaj +1 more source
Unusual death due to a bleeding from a varicose vein: a case report
Background Varicose veins are a common entity presenting a worldwide distribution. Although they are usually benign, sometimes are proved to be a threatening condition.
Fragkouli Kleio +5 more
doaj +1 more source

