Results 51 to 60 of about 322,631 (232)

Targeting Histamine H4 Receptor in the Rostral Ventromedial Medulla to Relieve Hypertension

Advanced Science, Volume 12, Issue 45, December 4, 2025.
H4R and its downstream TRPV1 channel mediate the excitatory effect of TMN histaminergic afferent inputs on GABAergic sympathoinhibitory neurons in RVMM. Intranasal delivery of selective H4R agonist VUF 8430 suppresses renal sympathetic outflow and elicits sustained depressor and bradycardia responses in SHRs and CUMS‐induced hypertensive rats ...
Ying Shi, Yang‐Xun Zhang, Jun‐Yi Chen, Sai Ma, Wei‐Xuan Xue, Wei Li, Qian‐Xiao Li, Bo Song, Ya‐Ting Li, Hong‐Yu Ma, Shu‐Tao Xie, Hong‐Zhao Li, Di‐Jun Chen, Qi‐Peng Zhang, Hui‐Jie Ma, Jian‐Jun Wang, Lei Yu, Xiao‐Yang Zhang, Jing‐Ning Zhu   +18 more
wiley   +1 more source

The Thigh Saphenous Vein Versus the Calf Saphenous Vein: Searching for the Optimal Conduit for Coronary Artery Bypass Grafting

Catheterization and Cardiovascular Interventions, Volume 106, Issue 7, Page 3665-3672, December 1, 2025.
ABSTRACT Background The quality of saphenous vein (SV) grafts can vary depending on the site from which they are harvested. However, few studies have compared SV grafts harvested from the thigh with those harvested from the calf to explore which is more appropriate for use in coronary artery bypass grafting (CABG). In this study, we evaluated the graft
Aidong Chen, Ke Pan
wiley   +1 more source

PIEZO Force Sensing in Vascular Biology: An Explosion of New Knowledge, Concepts and Opportunity

Advanced Science, Volume 12, Issue 41, November 6, 2025.
Knowledge of the remarkable mechanical force sensing and electrically transducing PIEZO1 and PIEZO2 channels is discussed across vascular biology and its cell types from the embryonic to adult stages in health, disease and old age. How the channels work, relate to other factors and signal for tissue responses to mechanical forces is debated.
David J Beech
wiley   +1 more source

Phenotypic Spectrum and Diagnostic Challenges in Klippel‐Trenaunay Syndrome: A Case Series

Clinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT Klippel‐Trénaunay syndrome (KTS) is a rare congenital disorder characterized by the triad of capillary malformations, venous varicosities, and soft tissue or bony hypertrophy. This case series highlights rare and atypical presentations of KTS, emphasizing the importance of a multidisciplinary diagnostic approach.
Marya Hameed, Tooba Ali, Md Ariful Haque
wiley   +1 more source

Assessment of Outcome in Patients Undergoing Endovenous Radiofrequency Ablation for Varicose Veins in a Community-based Hospital Using Venous Clinical Severity Score

Indian Journal of Vascular and Endovascular Surgery
Background: Varicose veins are one of the most prevalent conditions that significantly impact quality of life and can lead to severe complications if untreated.
S Raj, Lingaraj H Adavi, S. Sairam Subramanian   +2 more
doaj   +1 more source

Axial ablation versus terminal interruption of the reflux source (AAVTIRS): a randomised controlled trial

Trials, 2022
Background Treatment of superficial venous reflux has been shown to improve ulcer healing time and reduce the risk of ulcer recurrence. Terminal ablation of the reflux source (TIRS) is an alternative to formal endovenous ablation or surgery which can be ...
C. R. Keohane, D. Westby, M. Twyford, T. Ahern, W. Tawfick, S. R. Walsh   +5 more
doaj   +1 more source

Factors Associated With Quality of Life in Patients With Venous Leg Ulcers in a Community Setting: A Cross‐Sectional Study

Health Science Reports, Volume 8, Issue 11, November 2025.
ABSTRACT Background and Aims Quality of life is a well‐established determinant of physical and mental health outcomes in the general population. However, limited research has specifically examined factors influencing quality of life in individuals with venous leg ulcers (VLUs) using disease‐specific measures.
Jodi Christine McDaniel, Bohyun Kim, Dina Rose McGowan, Alai Tan   +3 more
wiley   +1 more source

Testing Sonication and Different Transport Media to Enhance Microbial Detection in Hard‐to‐Heal Venous Leg Ulcers

International Wound Journal, Volume 22, Issue 11, November 2025.
ABSTRACT Hard‐to‐heal wounds are frequently associated with underlying conditions such as diabetes, vascular disease, and biofilm‐related infections. Accurate identification of microbial origin is essential, but is often hindered by biofilms. This study evaluated whether sonication of wound dressings, combined with different sample transport methods ...
Adéla Holubová, Niels A. J. Cremers, Martin Krause, Lada Cetlová, Jana Matějková, Andrea Pokorná   +5 more
wiley   +1 more source

Physiotherapeutic procedure on the example of compression therapy in treatment of venous diseases

Journal of Education, Health and Sport, 2018
The aim of this study is an attempt to systematise the knowledge about physiotherapy in the process of treatment of vascular diseases, with particular focus on compression therapy.
Mateusz Curyło, Katarzyna Cienkosz, Marcin Mikos, Aleksandra Izabela Czerw, Jan Raczkowski   +4 more
doaj   +3 more sources

A Rare Case of Pyoderma Gangrenosum as a Complication of Ulcerative Colitis: A Case Report and Literature Review

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT This case highlights pyoderma gangrenosum, a rare but serious extraintestinal manifestation of ulcerative colitis, especially in patients presenting with atypical skin ulcers and a history of inflammatory bowel disease. The pathergy phenomenon and lesions were crucial diagnostic clues, and early recognition, along with prompt initiation of ...
Amin Shah, Anubhav Sharma, Agnimshwor Dahal, Prinsa Shrestha, Rahul Parajuli, Rebicca Pradhan, Bibek Shrestha   +6 more
wiley   +1 more source