Causal relationship between varicose veins and hydrocele: A bidirectional two-sample Mendelian randomization study [PDF]
SAGE Open MedicineObjective: This study aimed to investigate the causal relationship between varicose veins and hydroceles. Methods: Genetic data for varicose veins and hydroceles were extracted from a Genome-Wide Association Study (GWAS).
Chunzhi Guo, Yan Qu, Hong Liu
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Causal role of immune cells in varicose veins: insights from a Mendelian randomization study [PDF]
Scientific ReportsImmune factors play a pivotal role in the development of vascular diseases. However, research on the relationship between immune cells and the risk of varicose veins remains limited.
Qi-Feng Zhang, Qi-Li Liu
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Cold hypersensitivity in the lower extremities: an underappreciated symptom in patients with varicose veins [PDF]
Open HeartBackground This study aimed to investigate the frequently overlooked symptoms of cold hypersensitivity and heavy legs related to varicose veins in a large sample of patients.Methods Data on 8782 adults aged 30–70 years without a history of cancer were ...
Disline Manli Tantoh +5 more
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Varicose Veins: Prevalence and Associated Risk Factors among Women of Childbearing Age Attending a Primary Health Care Unit in Cairo, Egypt [PDF]
The Egyptian Family Medicine Journal, 2020 Background: Varicose veins are very common and affect individuals of all ages; however, unfortunately, their aetiology is partially understood. There is a scarcity of studies in Egypt investigating their prevalence and associated risk factors, especially
Saher G. Aly +4 more
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A study of etiology of secondary varicose veins
Archives of Clinical and Experimental Surgery, 2018 Introduction: Lower limb veins are most prone to having venous disorders and varicose veins are the biggest issue. Varicose veins can be grouped into Primary or Secondary Varicose veins.
Kshitij Arun Manerikar +4 more
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Factors associated with idiopathic adolescent scoliosis in female population - preliminary results [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2017 Introduction/Objective. Idiopathic scoliosis (IS) is an orthopedic condition of multifactorial origin. The aim of our study was to evaluate the factors that are associated with IS in female population and factors associated with varicose veins in females
Talić Goran +6 more
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Varicose veins and its risk factors among nurses at Dhulikhel hospital: a cross sectional study
BMC Nursing, 2020 Background Women in nursing professions are at high risk for developing varicose veins as it requires physical work and prolonged standing. The aim of the study is to estimate the current prevalence of varicose veins among nurses at Dhulikhel Hospital ...
Regan Shakya +3 more
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Genome-wide association analysis and replication in 810,625 individuals with varicose veins
Nature Communications, 2022 Although varicose veins are a common condition, the genetic basis is not well understood. Here, the authors find genetic variants associated with varicose veins and show that a higher polygenic risk score for varicose veins correlates with a greater ...
Waheed-Ul-Rahman Ahmed +10 more
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Frontiers in Physiology, 2019 ObjectiveVaricose veins are a common problem worldwide and can cause significant impairments in health-related quality of life, but the etiology and pathogenesis remain not well defined. This study aims to elucidate transcriptomic regulations of varicose
Jianbin Zhang +16 more
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Decreased PGE₂ content reduces MMP-1 activity and consequently increases collagen density in human varicose vein. [PDF]
PLoS ONE, 2014 Varicose veins are elongated and dilated saphenous veins. Despite the high prevalence of this disease, its pathogenesis remains unclear.In this study, we investigated the control of matrix metalloproteinases (MMPs) expression by prostaglandin (PG)E₂ ...
Ingrid Gomez +6 more
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