Results 111 to 120 of about 2,480,792 (309)

Numerical analysis on the dynamic response of a plate-and-frame membrane humidifier for PEMFC vehicles under various operating conditions

Open Physics, 2018
PEMFC needs to be maintained at an appropriate temperature and humidity in a rapidly changing environment for automobile applications. In this study, a pseudo-multi-dimensional dynamic model for predicting the heat and mass transfer performance of a ...
Yun Sungho, Cha Dowon, Song Kang Sub, Hong Seong Ho, Lee Sang Hun, Yang Wonseok, Kim Yongchan   +6 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Space shuttle SRM plume expansion sensitivity analysis [PDF]

The exhaust plumes of the space shuttle solid rocket motors can have a significant effect on the base pressure and base drag of the shuttle vehicle. A parametric analysis was conducted to assess the sensitivity of the initial plume expansion angle of ...
Penny, M. M., Smith, S. D., Tevepaugh, J. A.   +2 more
core   +1 more source

The passive operating mode of the linear optical gesture sensor

, 2017
The study evaluates the influence of natural light conditions on the effectiveness of the linear optical gesture sensor, working in the presence of ambient light only (passive mode).
Czuszynski, Krzysztof, Ruminski, Jacek, Wtorek, Jerzy   +2 more
core   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Study on the Electromagnetic Characteristics of a Twin Inverter System EV Traction Motor Under Various Operating Conditions

Energies
This paper analyzes the electromagnetic characteristics of an interior permanent magnet synchronous motor (IPMSM) for electric vehicle traction under various control imbalance conditions in a twin inverter system, assuming that one of the inverters fails
Jae-Gak Shin, Hong-Jae Jang, Tae-Su Kim, Ki-Chan Kim   +3 more
doaj   +1 more source

Design of the Submerged Floating Tunnel operating under various conditions

Procedia Engineering, 2010
AbstractIn Norway there has been identified several crossings with a variety of different conditions under which a Submerged Floating Tunnel, SFT or Archimedes Bridge, may be used. In the Høgsfjord project whose feasibility was well documented before the project was stopped for local political reasons the length was some 1400 m, the water depth about ...
openaire   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Pressurization System under Various Operating Conditions for Smoke Control

Journal of the Korean Society of Hazard Mitigation
The importance of smoke control systems has been emphasized for a safe evacuation and efficient firefighting activities during fire situations. To protect stairwells from smoke hazards, ‘Design Guide for Smoke Control System of Special Evacuation Stairwell and Lobby (NFPC501A)’ has been presented. In domestic area, pressurization systems utilize an air
openaire   +1 more source