Results 61 to 70 of about 3,762,442 (310)

Case Report: Decoding genetic risks of vascular parkinsonism: a case series

Frontiers in Genetics
BackgroundVascular parkinsonism (VaP) is a subtype of parkinsonism which needs better characterization of its risks and determinants.ObjectiveThe aim of this report is to present an understanding of genetic risks of vascular parkinsonism.MethodsFive ...
Ali Shalash, Salma El-Shafie, Peter George, Tamer Roushdy, Mai Fathy, Mohamed H. Yousef, Mahmoud El-Belkimy, Mohamed Ossama Abdulghani, Mohamed Salama   +8 more
doaj   +1 more source

Live-imaging of endothelial Erk activity reveals dynamic and sequential signalling events during regenerative angiogenesis

eLife, 2021
The formation of new blood vessel networks occurs via angiogenesis during development, tissue repair, and disease. Angiogenesis is regulated by intracellular endothelial signalling pathways, induced downstream of vascular endothelial growth factors ...
Kazuhide S Okuda, Mikaela S Keyser, David B Gurevich, Caterina Sturtzel, Elizabeth A Mason, Scott Paterson, Huijun Chen, Mark Scott, Nicholas D Condon, Paul Martin, Martin Distel, Benjamin M Hogan   +11 more
doaj   +1 more source

Surgeon Speaks-Paul J. DiMuzio, MD, FACS [PDF]

, 2014
“Patients with extensive acute deep vein thrombosis (DVT) of the legs provide an excellent example of why effective medical-surgical collaboration is so important.

core   +1 more source

Branching principles of animal and plant networks identified by combining extensive data, machine learning, and modeling [PDF]

, 2020
Branching in vascular networks and in overall organismic form is one of the most common and ancient features of multicellular plants, fungi, and animals.
Bentley, Lisa P., Brummer, Alexander B, Buzzard, Vanessa, Enquist, Brian J., Gray, Andrew, Lymperopoulos, Panagiotis, Oliveras, Imma, Savage, Van M., Shen, Jocelyn, Tekin, Elif   +9 more
core   +3 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

The Role of Vascular-Immune Interactions in Modulating Chemotherapy Induced Neuropathic Pain

Frontiers in Pharmacology, 2022
Chemotherapy causes sensory disturbances in cancer patients that results in neuropathies and pain. As cancer survivorships has dramatically increased over the past 10 years, pain management of these patients is becoming clinically more important. Current
Tameille Valentine, Lydia Hardowar, Jasmine Elphick-Ross, Richard P. Hulse, Mark Paul-Clark   +4 more
doaj   +1 more source

Vascular Stem Cells in Vascular Remodeling and Diseases [PDF]

, 2013
BACKGROUND: Blood vessels are a source of stem and progenitor cells, which likely contribute to a variety of vascular processes and diseases. Emerging concepts in this field could influence therapeutic approaches to diseases of blood vessels such as ...
Meiliana, A. (Anna), Wijaya, A. (Andi)
core  

Homocysteine in cerebrovascular disease: An independent risk factor for subcortical vascular encephalopathy [PDF]

, 2001
Hyperhomocysteinemia is a risk factor for obstructive large-vessel disease. Here, we studied plasma concentrations of homocysteine and vitamins in patients suffering from subcortical vascular encephalopathy (SVE), a cerebral small-vessel disease leading ...
Aufenanger, Johannes, Bertsch, Thomas, Casarin, Wendy, Fassbender, Klaus, Höly, Sabine, Kuehl, Sandra, Mielke, Orell, Muehlhauser, Frank, Ragoschke, Andreas, Walter, Silke, Zimmer, Wilma   +10 more
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

High throughput RNAi assay optimization using adherent cell cytometry

Journal of Translational Medicine, 2011
Background siRNA technology is a promising tool for gene therapy of vascular disease. Due to the multitude of reagents and cell types, RNAi experiment optimization can be time-consuming.
Pradhan Leena, Chun Maggie, Nabzdyk Christoph S, LoGerfo Frank W   +3 more
doaj   +1 more source