Abstract Purpose Retinal telangiectatic capillaries (TelCaps) are microvascular abnormalities associated with chronic vascular macular oedema and suboptimal response to intravitreal therapy. Targeted laser photocoagulation is beneficial but requires precise localization using indocyanine green angiography (ICG‐A), the reference standard. However, ICG‐A
Lucas Unger +7 more
wiley +1 more source
Pearls and Pitfalls in the Management of Vascular Anomalies. [PDF]
Sanon O, Henderson A, Rosen RJ.
europepmc +1 more source
ABSTRACT Aim Childhood ischemic stroke is rare but causes substantial long‐term morbidity, and its heterogeneous aetiology complicates timely diagnosis and management. Methods We conducted a retrospective population‐based observational study using hospital data and chart review to describe diagnostics, treatment and outcomes of ischemic stroke in ...
Jussi V. Leinonen +8 more
wiley +1 more source
Non‐Alzheimer Aβ deposits in the human CNS: Implications with hypoxia and related conditions
An Aβ deposit in a non‐Alzheimer's brain from an individual who experienced hypoxia/energy failure. Abstract We recently reported the deposition of Aβ in the frontal cortex of individuals who died of acute coronavirus disease 2019 (COVID‐19), or who did not have COVID‐19 but had respiratory distress, or infants with severe cardiac malformations.
Esma Karlovich +5 more
wiley +1 more source
A new approach to the treatment of microcystic lymphatic malformations in children
Dan Song, Jing Li, Liang Wang, Lei Guo
doaj +1 more source
A rare arteriovenous communication between left testicular vein with left accessory renal artery and multiple renal vascular anomalies: understanding the genetic and embryological perspective. [PDF]
Sangma SS, Rani N, Jp J, Kumar R.
europepmc +1 more source
Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown +2 more
wiley +1 more source
Anti-neuroinflammatory therapy for non-pulsatile tinnitus in patients with sinus vascular anomalies: preliminary result on two cases. [PDF]
Di Stadio A +5 more
europepmc +1 more source
Targeting protein–protein interactions with reversible covalent modalities: Non‐cysteine chemistries
Abstract Protein–protein interactions (PPIs) are central to diverse cellular functions, and represent a rapidly expanding class of therapeutic targets. Advancements in covalent drug design have enabled small‐molecule drugs to overcome challenges associated with engaging these targets, such as limited durations of action and difficult‐to‐drug (expansive,
Ruchira Basu, Steven Fletcher
wiley +1 more source
Vascular Anomalies of the Head and Neck - Case Series. [PDF]
Soumya MS, Sreenivas V, Thomas TT.
europepmc +1 more source

