Results 111 to 120 of about 1,887,887 (334)

Somatic activating mutations in PIK3CA cause generalized lymphatic anomaly

Journal of Experimental Medicine, 2018
Generalized lymphatic anomaly (GLA) is a vascular disorder characterized by diffuse or multifocal lymphatic malformations (LMs). The etiology of GLA is poorly understood.
L. Rodríguez-Laguna, Noelia Agra, K. Ibáñez, Gloria Oliva-Molina, G. Gordo, Noor Khurana, Devon Hominick, M. Beato, I. Colmenero, Gonzalo Herranz, Juan M Torres Canizalez, Rebeca Rodríguez Pena, E. Vallespín, R. Martín-Arenas, Ángela del Pozo, C. Villaverde, A. Bustamante, C. Ayuso, P. Lapunzina, J. López-Gutiérrez, M. Dellinger, V. Martínez-Glez   +21 more
semanticscholar   +1 more source

The role of Rho GTPases in facial morphogenesis

Developmental Dynamics, EarlyView.
The role of small GTPases, RHOA, RAC1, and CDC42 and pathway mediators is reviewed in the context of embryonic facial development. Lip fusion requires cytoskeletal remodeling during morphogenesis of the facial processes and during lip fusion. Fnm, frontonasal mass; lnp, lateral nasal process; mnp, medial nasal process; mxp, maxillary process; np, nasal
Isra Ibrahim, Joy M. Richman
wiley   +1 more source

Transient Hemi-Lower Limb Ischemia in the Newborn: Arterial Thrombosis or Persistent Sciatic Artery?

American Journal of Perinatology Reports, 2017
Neonatal thromboembolism occurs with various predispositions and triggers. Early diagnosis of the thrombosis is challenging and essential for the therapeutic interventions.
Makiko Kirino, Masayuki Ochiai, Masako Ichiyama, Hirosuke Inoue, Takeshi Kusuda, Tadamune Kinjo, Masataka Ishimura, Shouichi Ohga   +7 more
doaj   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Computed Tomographic Hepatic Volumetry in Dogs with Congenital Portosystemic Shunts

Veterinary Sciences
CTHV is a non-invasive and accurate method for assessing liver volume in dogs. CTHV has not been studied in each type of extrahepatic PSS in dogs. This study aimed to use CTHV to compare liver volumes in dogs with different types of PSSs that had been ...
Hitomi Kurihara, George Moore, Masahiro Murakami   +2 more
doaj   +1 more source

Seizure control after radiosurgical treatment in patients with cerebral arteriovenous malformations: An observational study

Epilepsia, EarlyView.
Abstract Objective Seizures are among the most common symptoms of cerebral arteriovenous malformations (AVMs). Although the main goal of AVM treatment remains complete obliteration, seizure control has become an important treatment aspect in recent years.
Philip Lederer, Muhammet Dogan, Dorian Hirschmann, Beate Kranawetter, Anna Cho, Philipp Goebl, Christian Dorfer, Brigitte Gatterbauer, Karl Rössler, Philippe Dodier, Wei‐Te Wang, Gerhard Bavinzski, Arthur Hosmann, Wolfgang Serles, Josa M. Frischer   +14 more
wiley   +1 more source

Aberrant Right Subclavian Artery With a Bicarotid Trunk: A Rare Cause of Stridor in Infants

Clinical Case Reports
The aberrant right subclavian artery represents a rare vascular anomaly that must be considered in the differential diagnosis of infants experiencing respiratory distress and feeding difficulties.
Mohammad Alashqar, Israa Salman, Shahd Saadeh, Seba Lubbadeh, Osayd Khasati   +4 more
doaj   +1 more source

First stage reconstruction following surgical excision of a large arteriovenous malformation of the lower lip and tongue

Медицина болю
Arteriovenous malformations (AVMs) are rare congenital lesions caused by deformity of the blood vessels. Around half of the AVMs are found in the craniofacial area, presenting with a progressive high-
Jenisa Kamayana, I Adnyana, Agus Hamid, I Sanjaya   +3 more
doaj   +1 more source

A Potentially Catastrophic Anatomical Variation: Aberrant Internal Carotid Artery in the Middle Ear Cavity

Case Reports in Otolaryngology, 2013
Aberrant internal carotid artery (ICA) is a rare but a very important vascular anomaly of temporal bone. Misdiagnosis of the anomaly may lead to massive hemorrhage and severe complications during otologic procedures.
Togay Muderris, Sami Bercin, Ergun Sevil, Huseyin Cetin, Muzaffer Kiris   +4 more
doaj   +1 more source

Isolated interrupted inferior vena cava with azygos continuation mimicking paraesophageal lymph node enlargement

Monaldi Archives for Chest Disease, 2016
We report a case of interrupted inferior vena cava with azygos continuation diagnosed as a isolated finding in a patient with lung carcinoma. Findings of the unopacified CT scan initially simulated a paraesophageal lymphadenopathy.
U. Yılmaz, H. Halilcolar, I. Unsal, S. Yapıcıoglu, Y. Yıldırım, M. Apaydın   +5 more
doaj   +1 more source