Results 261 to 270 of about 867,365 (301)

Biology of Vascularized Bone Grafts

Orthopedic Clinics of North America, 1987
Vascularized canine fibular autografts demonstrated improved biologic and mechanical characteristics 3 months after surgery when compared with nonvascularized controls. The vascularized proximal fibula maintained its overall architecture without bony collapse or significant bone turnover. The strength and stiffness of these grafts were approximately 40
V M, Goldberg, J W, Shaffer, G, Field, D T, Davy   +3 more
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Vascular Biology of the Isoprostanes

Journal of Vascular Research, 2001
Isoprostanes are a family of compounds produced from polyunsaturated fatty acids via a free-radical-catalysed mechanism. F₂-isoprostanes are prostaglandin F_2α isomers derived from arachidonic acid. These compounds induce potent vasoconstriction, mediated primarily by TP receptor stimulation, and in some ...
J L, Cracowski, P, Devillier, T, Durand, F, Stanke-Labesque, G, Bessard   +4 more
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Developmental Vascular Biology

2018
Our understanding of molecular processes governing embryonic vascular development has largely come from in vivo and ex vivo studies using model organisms (laboratory mice, chick, and xenopus embryos) and in vitro studies using human umbilical vein endothelial cells (HUVECs) or human embryonic stem cell lines (hESCs).
Sheila N. Ganti, Mark W. Majesky, Jonathan A. Perkins   +2 more
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Vascular stenosis: biology and interventions

Current Opinion in Nephrology and Hypertension, 2007
The aim of this review will be to summarize recent concepts pertaining to the pathophysiology of dialysis access stenosis and to then use this information to highlight novel interventions (both diagnostic and therapeutic) for dialysis access dysfunction.
Prabir, Roy-Chaudhury, Timmy C, Lee
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The biology of vascular calcification

2020
Vascular calcification (VC), characterized by different mineral deposits (i.e., carbonate apatite, whitlockite and hydroxyapatite) accumulating in blood vessels and valves, represents a relevant pathological process for the aging population and a life-threatening complication in acquired and in genetic diseases.
Quaglino D., Boraldi F., Lofaro F. D.
openaire   +3 more sources

Biology of vascular mural cells

Development, 2023
ABSTRACT The vasculature consists of vessels of different sizes that are arranged in a hierarchical pattern. Two cell populations work in concert to establish this pattern during embryonic development and adopt it to changes in blood flow demand later in life: endothelial cells that line the inner surface of blood vessels, and adjacent ...
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Nitric oxide in vascular biology

Journal of Thrombosis and Haemostasis, 2003
Nitric oxide is a highly versatile heterodiatomic molecule that effects a variety of actions in the vasculture. Originally identified as a principal determination of vascular tone, nitric oxide has since been recognized to exert anti thrombotic, antiproliferative, and anti-inflammatory effects in the vasculture.
G, Walford, J, Loscalzo
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The vascular biology of atherosclerosis

The American Journal of Medicine, 2003
Despite many advances in cardiology, atherosclerosis remains a major medical problem. This is especially the case for individuals with insulin resistance and type 2 diabetes mellitus. Atherosclerotic lesions can develop as early as the second decade of life and progress into clinical disease over time.
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Molecular biology of vascular hypertrophy

European Journal of Pharmacology, 1990
In chronic models of hypertension such as the spontaneously hypertensive rat (SHR), thickening of the media of large arteries occurs mainly through smooth muscle cell (SMC) hypertrophy accompanied by DNA replication resulting in large polyploid cells. In resistance vessels of SHR, medial hypertrophy occurs through a hyperplastic response.
J H, Campbell, G, Tachas, M J, Black, G, Cockerill, G R, Campbell   +4 more
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Hemodynamics and Vascular Endothelial Biology

Journal of Cardiovascular Pharmacology, 1993
The vascular endothelium, as the interface between flowing blood and the underlying vessel wall, not only resides in a hemodynamic environment, but also is a mediator of flow-related influences. In recent years, particularly with the advent of cell culture studies, much has been learned about the effects of this mechanical environment.
R M, Nerem, D G, Harrison, W R, Taylor, R W, Alexander   +3 more
openaire   +2 more sources