Results 241 to 250 of about 102,531 (290)

A rare ORAI1 missense variant associates with risk of vascular diseases in White British adults. [PDF]

PLoS One
Shawer H, Cheng CW, Hemmings KE, Aldawsari AM, Revilla-González G, Stocco F, Shi J, Beech DJ, Bailey MA.   +8 more
europepmc   +1 more source

Strategic Design of Soft Actuators in Translational Medical Robotics for Human‐Centered Healthcare

Advanced Robotics Research, EarlyView.
Soft robotics enables biocompatible, compliant medical devices, but clinical translation requires design‐driven engineering beyond materials. This perspective reviews implantable, surgical, and wearable systems by actuation mechanism, highlighting how optimized architectures and integration improve mechanical interfacing, adaptability, and durability ...
Ho Jun Jin, Jimin Kim, Inho Kim, Bong Hoon Kim   +3 more
wiley   +1 more source

The Relationship Between Hippocampal Cerebrovascular Reactivity and Brain Structure in Older Age. [PDF]

Hum Brain Mapp
Wang C, Jobbins L, Reid G, Hobden G, Patel R, Mackay CE, Ebmeier KP, Pinto J, Bulte D, Kivimäki M, Singh-Manoux A, Suri S.   +11 more
europepmc   +1 more source

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

Comparison of the efficacy of spiral CT combined with advanced multiplanar reconstruction in detecting the progression of pneumoconiosis. [PDF]

Front Med (Lausanne)
Liu Y, Zhu N, Sun HZ, Ji P.
europepmc   +1 more source

High Humidity Exacerbates Psoriasiform Skin Disease Relapse by Increasing Tissue‐Resident Memory T Cells via Altering Skin Microbiota

Advanced Science, EarlyView.
We demonstrated that high humidity worsened psoriasis relapse in murine psoriasiform skin inflammation by increasing skin‐resident memory CD8+ cells via upregulating IL‐15Rα on keratinocytes. The increases in IL‐15Rα and memory CD8+ cells were attributed to S. nepalensis and its metabolite ADMA in skin exposed to high humidity.
Chun‐Ling Liang, Yuchao Chen, Chuanjian Lu, Huazhen Liu, Fenglian Qin, Sisi Dai, Feifei Qiu, Haiming Chen, Weihui Lu, Jonathan S. Bromberg, Zhenhua Dai   +10 more
wiley   +1 more source

Enhanced expression of the <i>ScTpx2</i> gene confers tolerance to drought stress in transgenic sugarcane. [PDF]

GM Crops Food
Tirabante Terrones N, Gonçalves VR, Nelissen H, Gonzalez N, Souza Bernardes W, Faleiro de Lima R, Mayer J, Inzé D, Menossi M.   +8 more
europepmc   +1 more source

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

Advanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun, Changying Jing, Martina Tetti, Siyuan Gong, Jia Wei, Yingxian Pang, Martin Reincke, Tracy Ann Williams   +7 more
wiley   +1 more source

The importance of contrast fluoroscopy during left bundle branch area pacing: A case report of septal venous channel perforation during implantation. [PDF]

HeartRhythm Case Rep
Zhou Z, Kardas K, Clark J, Margulescu AD.   +3 more
europepmc   +1 more source

Rate-Dependent Painful Left Bundle Branch Block (PLBBB) in a Structurally Normal Heart. [PDF]

Cureus
Barbosa D, Gomes Campos I, Magalhães N, Ponte Monteiro J.   +3 more
europepmc   +1 more source