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Vascular dementia [PDF]

open access: yesLancet, The, 2015
Vascular dementia is one of the most common causes of dementia after Alzheimer's disease, causing around 15% of cases. However, unlike Alzheimer's disease, there are no licensed treatments for vascular dementia.
John T O'Brien, Alan J Thomas
exaly   +1 more source

Clinical Trials of New Drugs for Vascular Cognitive Impairment and Vascular Dementia [PDF]

open access: goldInternational Journal of Molecular Sciences, 2022
Tran Thanh Duy Linh   +2 more
exaly   +2 more sources

Inflammation and Rho-Associated Protein Kinase-Induced Brain Changes in Vascular Dementia

open access: yesBiomedicines, 2022
Patients with vascular dementia, caused by cerebral ischemia, experience long-term cognitive impairment due to the lack of effective treatment. The mechanisms of and treatments for vascular dementia have been investigated in various animal models ...
Eun Chae Lee   +11 more
doaj   +1 more source

Pathogenesis of Cognitive Deficits Induced by Hippocampal Mitochondrial Dysfunction in Vascular Dementia: a Review of the Latest Developments [PDF]

open access: yesZhongguo quanke yixue, 2022
Hippocampal mitochondrial dysfunction is closely related to cognitive deficits in vascular dementia. We reviewed the latest developments in the internal associations of hippocampal mitochondrial dysfunction with cognitive deficits in vascular dementia ...
Xin ZHANG, Ping LI, Yuhan WANG, Caiping ZHENG, Xiaoyan DENG, Luming QI, Juan LI, Yijing JIANG, Lina XIA
doaj   +1 more source

Depression and anxiety in acute ischemic stroke involving the anterior but not paramedian or inferolateral thalamus

open access: yesFrontiers in Psychology, 2023
Background and objectivesEmotional and cognitive deficits are prevalent in strokes involving the thalamus. In contrast to cognitive deficits, emotional deficits have not been studied prospectively in isolated thalamic stroke.MethodsIn 37 ischemic ...
Anne-Carina Scharf   +8 more
doaj   +1 more source

Clinical Risk Score for Predicting Vascular Dementia after Ischemic Stroke in Thailand

open access: yesStroke Research and Treatment, 2022
Background. Poststroke dementia is an important consequence of stroke and warrants early prevention, detection, and management. The objective of the study was to develop a simple clinical risk score for predicting risk of vascular dementia in patients ...
Pornpatr A. Dharmasaroja   +1 more
doaj   +1 more source

Sleep and Wakefulness Disorders in Vascular Cognitive Impairment

open access: yesАнналы клинической и экспериментальной неврологии, 2020
Dementia is a pathology that leads to disability and significantly affects the quality of life of patients and their relatives. The study and development of treatment methods for dementia is a priority in medicine, given the rate of growth in the number ...
Tatyana B. Merkulova   +2 more
doaj   +1 more source

Berberine for prevention of dementia associated with diabetes and its comorbidities: A systematic review [PDF]

open access: yes, 2020
Background A growing number of epidemiological studies indicate that metabolic syndrome (MetS) and its associated features play a key role in the development of certain degenerative brain disorders, including Alzheimer’s disease and vascular dementia ...
Bell, J.D.   +9 more
core   +1 more source

Habitual glucosamine use, APOE genotypes, and risk of incident cause-specific dementia in the older population

open access: yesAlzheimer’s Research & Therapy, 2023
Background The relationship of glucosamine use with incident dementia in the older population remains uncertain. We aimed to evaluate the longitudinal association between habitual glucosamine supplement and the risk of cause-specific dementia and examine
Chun Zhou   +8 more
doaj   +1 more source

Isolated Subtle Neurological Abnormalities in Mild Cognitive Impairment Types [PDF]

open access: yes, 2020
Background: Isolated, subtle neurological abnormalities (ISNA) are commonly seen in aging and have been related to cerebral small vessel disease (SVD) and subcortical atrophy in neurologically and cognitively healthy aging subjects.
Azzarello, Delia   +7 more
core   +1 more source

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