Results 21 to 30 of about 16,767,791 (307)

Highly Efficient Synthetic CRISPR RNA/Cas9-Based Mutagenesis for Rapid Cardiovascular Phenotypic Screening in F0 Zebrafish

Frontiers in Cell and Developmental Biology, 2021
The zebrafish is a valuable vertebrate model to study cardiovascular formation and function due to the facile visualization and rapid development of the circulatory system in its externally growing embryos.
Rachael E. Quick, Rachael E. Quick, Luke D. Buck, Luke D. Buck, Sweta Parab, Sweta Parab, Zane R. Tolbert, Zane R. Tolbert, Ryota L. Matsuoka, Ryota L. Matsuoka   +9 more
doaj   +1 more source

Ifi30 Is Required for Sprouting Angiogenesis During Caudal Vein Plexus Formation in Zebrafish

Frontiers in Physiology, 2022
Interferon-gamma-inducible protein 30 (IFI30) is a critical enzyme that mainly exists in immune cells and functions in reducing protein disulfide bonds in endocytosis-mediated protein degradation.
Xiaoning Wang, Xiaojuan Ge, Yinyin Qin, Dong Liu, Changsheng Chen   +4 more
doaj   +1 more source

Development Effectiveness Overview (DEO) 2023

, 2023
The Development Effectiveness Overview (DEO) is an annual report produced by the IDB Group to share the results and impact of its work in Latin America and the Caribbean.
Inter-American Development Bank
core   +1 more source

Influence of Switchgrass TDIF-like Genes on Arabidopsis Vascular Development

Frontiers in Plant Science, 2021
As a member of the CLAVATA3 (CLV3)/EMBRYO SURROUNDING REGION (CLE) family, the dodecapeptide tracheary element differentiation inhibitory factor (TDIF) has a major impact on vascular development in plants.
Dongdong Tian, Dongdong Tian, Jingwen Tang, Liwen Luo, Zhe Zhang, Kebing Du, Kebing Du, Robert M. Larkin, Xueping Shi, Xueping Shi, Bo Zheng, Bo Zheng   +11 more
doaj   +1 more source

TALE and Shape: How to Make a Leaf Different

Plants, 2013
The Three Amino acid Loop Extension (TALE) proteins constitute an ancestral superclass of homeodomain transcription factors conserved in animals, plants and fungi. In plants they comprise two classes, KNOTTED1-LIKE homeobox (KNOX) and BEL1-like homeobox (
Elisabetta Di Giacomo, Maria Adelaide Iannelli, Giovanna Frugis   +2 more
doaj   +1 more source

PRDM16 regulates arterial development and vascular integrity

Frontiers in Physiology, 2023
Proper vascular formation is regulated by multiple signaling pathways. The vascular endothelial growth factor (VEGF) signaling promotes endothelial proliferation.
Michael Thompson, Michael Thompson, Masahide Sakabe, Masahide Sakabe, Mark Verba, Mark Verba, Jiukuan Hao, Stryder M. Meadows, Stryder M. Meadows, Q. Richard Lu, Q. Richard Lu, Mei Xin, Mei Xin   +12 more
doaj   +1 more source

Agaricus bisporus-Derived Glucosamine Hydrochloride Regulates VEGF through BMP Signaling to Promote Zebrafish Vascular Development and Impairment Repair

Life, 2023
Glucosamine hydrochloride (GAH) is a natural component of glycoproteins present in almost all human tissues and participates in the construction of human tissues and cell membranes.
Jiarui Sun, Qici Wu, Yuxin Wei, Wei Zhao, Haokun Lv, Wei Peng, Jiayi Zheng, Yixuan Chen, Zhengsen Wang, Yutian Pan, Yu Xue   +10 more
doaj   +1 more source

YAP and TAZ regulate adherens junction dynamics and endothelial cell distribution during vascular development

eLife, 2018
Formation of blood vessel networks by sprouting angiogenesis is critical for tissue growth, homeostasis and regeneration. How endothelial cells arise in adequate numbers and arrange suitably to shape functional vascular networks is poorly understood ...
Filipa Neto, Alexandra Klaus-Bergmann, Yu Ting Ong, Silvanus Alt, Anne-Clémence Vion, Anna Szymborska, Joana R Carvalho, Irene Hollfinger, Eireen Bartels-Klein, Claudio A Franco, Michael Potente, Holger Gerhardt   +11 more
doaj   +1 more source

Sustained Angiopoietin-2 Expression Disrupts Vessel Formation and Inhibits Glioma Growth

Neoplasia: An International Journal for Oncology Research, 2006
Systematic analyses of the expression of angiogenic regulators in cancer models should yield useful information for the development of novel therapies for malignant gliomas.
Ok-Hee Lee, Juan Fueyo, Jing Xu, W.K. Alfred Yung, Michael G. Lemoine, Frederick F. Lang, B. Nebiyou Bekele, Xian Zhou, Marta A. Alonso, Kenneth D. Aldape, Gregory N. Fuller, Candelaria Gomez-Manzano   +11 more
doaj   +1 more source

Single Cell Analysis in Vascular Biology

Frontiers in Cardiovascular Medicine, 2020
The ability to quantify DNA, RNA, and protein variations at the single cell level has revolutionized our understanding of cellular heterogeneity within tissues.
Nicholas W. Chavkin, Karen K. Hirschi, Karen K. Hirschi   +2 more
doaj   +1 more source