Results 121 to 130 of about 11,970,410 (409)

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Alzheimer and vascular brain diseases: Focal and diffuse subforms. [PDF]

, 2015
Alois Alzheimer is best known for his description of the pre-senile neurodegenerative disease named after him. However, his previous interest in vascular brain diseases, underlying cognitive and behavioral changes, was very strong. Besides describing the
Engelhardt, Eliasz, Grinberg, Lea T
core   +2 more sources

Long-term follow-up in adults after tetralogy of Fallot repair

Cardiovascular Ultrasound, 2018
Background Tetralogy of Fallot (ToF) is the most common cyanotic congenital heart disease and the population of ToF repair survivors is growing rapidly. Adults with repaired ToF develop late complications.
Natalia Dłużniewska, Piotr Podolec, Maciej Skubera, Monika Smaś-Suska, Jacek Pająk, Małgorzata Urbańczyk-Zawadzka, Wojciech Płazak, Maria Olszowska, Lidia Tomkiewicz-Pająk   +8 more
doaj   +1 more source

Vascular Inflammation and Oxidative Stress: Major Triggers for Cardiovascular Disease

Oxidative Medicine and Cellular Longevity, 2019
Cardiovascular disease is a leading cause of death and reduced quality of life, proven by the latest data of the Global Burden of Disease Study, and is only gaining in prevalence worldwide.
S. Steven, Katie Frenis, M. Oelze, S. Kalinovic, Marin Kuntić, María Teresa Bayo Jiménez, K. Vujacic-Mirski, Johanna Helmstädter, Swenja Kröller-Schön, T. Münzel, A. Daiber   +10 more
semanticscholar   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Homocysteine and vascular disease

Journal of British Surgery, 1995
Abstract There is increasing evidence that a raised blood level of homocysteine (HC) is a risk factor for premature atherosclerosis. With a gene frequency between one in 70 and one in 200 this condition may be more common than previously thought.
Jamie Y. Jeremy, Gerard Stansby, CS Berwanger   +2 more
openaire   +3 more sources

Sex-specific relevance of diabetes to occlusive vascular and other mortality : a collaborative meta-analysis of individual data from 980 793 adults from 68 prospective studies [PDF]

, 2018
Background: Several studies have shown that diabetes confers a higher relative risk of vascular mortality among women than among men, but whether this increased relative risk in women exists across age groups and within defined levels of other risk ...
Aoki, N, Arnesen, E, Aromaa, A, Aromaa, A, Assmann, G, Bachman, DL, Baigent, C, Bartholomew, H, Benetos, A, Bengtsson, C, Bennett, D, Bjorkelund, C, Blackburn, H, Bonaa, K, Boyle, E, Broadhurst, R, Carstensen, J, Chambless, L, Chen, Z, Clarke, R, Collaboration, PS, Collins, R, Collins, R, Cox, C, Criqui, MH, Curb, JD, D'Agostino, R, Date, C, De Backer, G, De Bacquer, D, DeBacquer, D, Dhaliwal, SS, Dobson, A, Dobson, AJ, Ducimetiere, P, Duffy, S, Eliassen, H, Emberson, JR, Empana, J, Fang, X, Garcia-Palmieri, M, Gazes, P, Giles, GG, Gillis, C, Gnatiuc, L, Goldbourt, U, Gu, D, Gu, DF, Guasch-Ferre, M, Guize, L, Haheim, L, Halsey, J, Hart, C, Hart, C, Hashimoto, S, Heng, D, Herrington, WG, Hjermann, I, Ho, SC, Hobbs, M, Hole, D, Hole, D, Holme, I, Horibe, H, Horibe, H, Hozawa, A, Hu, F, Hughes, K, Huxley, R, Huxley, RR, Imai, K, Imai, Y, Iso, H, Iso, H, Iso, H, Jackson, R, Jacobs, D, Jamrozik, K, Jee, SH, Jensen, G, Jiang, CQ, Johansen, NB, Jousilahti, P, Jr, JDR, Kagaya, M, Keller, J, Kim, HC, Kim, IS, Kita, Y, Kita, Y, Kitamura, A, Kitamura, A, Kitamura, A, Knekt, P, Knuiman, MW, Kornitzer, M, Kromhout, D, Kromhout, D, Kronmal, R, Lam, TH, Law, M, Lee, J, Leon, DA, Leon, DA, Leren, P, Levy, D, Lewington, S, Lewington, S, Lissner, L, Luepker, R, Luszcz, M, MacMahon, S, MacMahon, S, MacMahon, S, Maegawa, H, Marmot, M, Matsutani, Y, Meade, T, Morris, J, Morris, R, Murayama, T, Naito, Y, Naito, Y, Nakamura, M, Nakayama, T, Neaton, J, Nietert, PJ, Niki, I, Nishimoto, Y, Norton, R, Nozaki, A, Ohkubo, T, Okayama, A, Pan, WH, Pan, WH, Peters, SAE, Peto, R, Peto, R, Puska, P, Qizilbash, N, Reunanen, A, Rodgers, A, Rodgers, A, Saitoh, S, Sakata, K, Sato, S, Sato, S, Sato, S, Schnohr, P, Schulte, H, Selmer, R, Sharp, D, Sherliker, P, Shifu, X, Shimamoto, K, Shipley, M, Silbershatz, H, Smith, GD, Smith, GD, Smith, GD, Sorlie, P, Sritara, P, Studies, APC, Suh, I, Suh, I, Sutherland, SE, Sweetnam, P, Tamakoshi, A, Tanaka, H, Thomsen, T, Tominaga, S, Tomita, M, Tornberg, S, Tunstall-Pedoe, H, Tunstall-Pedoe, H, Tuomilehto, J, Tuomilehto, J, Tverdal, A, Ueshima, H, Ueshima, H, Ueshima, H, Ueshima, H, Ueshima, H, Vartiainen, E, Wald, N, Wannamethee, SG, Welborn, TA, Whincup, P, Whitlock, G, Whitlock, G, Willett, W, Woo, J, Woodward, M, Woodward, M, Wu, ZL, Wu, ZL, Yao, SX, Yarnell, J, Yokoyama, T, Yoshiike, N, Zhang, XH   +200 more
core   +6 more sources

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS): Document covering atherosclerotic disease of extracranial carotid and vertebral, mesenteric, renal, upper and lower extremity arteriesEndorsed b

European Heart Journal, 2018
2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS) : Document covering atherosclerotic disease of extracranial carotid and vertebral, mesenteric ...
V. Aboyans, Jean-Baptiste Ricco, Marie-Louise Bartelink, Martin Björck, M. Brodmann, T. Cohnert, Jean-Philippe Collet, Martin Czerny, Marco De Carlo, Sebastian Debus, Christine Espinola-Klein, Thomas Kahan, Serge Kownator, Lucia Mazzolai, A. R. Naylor, M. Roffi, Joachim Röther, M. Sprynger, M. Tendera, Gunnar Tepe, M. Venermo, C. Vlachopoulos, I. Desormais, Petr Widimsky, Philippe Kolh, Stefan Agewall, Héctor Bueno, Antonio Coca, G. D. de Borst, V. Delgado, Florian Dick, Çetin Erol, Marc Ferrini, S. Kakkos, H. Katus, J. Knuuti, J. Lindholt, Heinrich P. Mattle, P. Pienia̧žek, M. Piepoli, Dierk Scheinert, Horst Sievert, Iain A Simpson, Jakub Sulženko, J. Tamargo, L. Tokgozoglu, A. Torbicki, N. Tsakountakis, J. Tuñón, M. D. de Céniga, Stephan Windecker, J. Zamorano, Emanuele Barbato, I. Coman, V. Dean, Donna Fitzsimons, O. Gaemperli, Gerhard Hindricks, Bernard Iung, P. Juni, Patrizio Lancellotti, Christophe Leclercq, Theresa A McDonagh, P. Ponikowski, D. Richter, E. Shlyakhto, Iain A Simpson, P. Zelveian, Markus Haumer, Dzmitry Isachkin, Tine De Backer, M. Dilić, Ivo Petrov, M. V. Kirhmajer, D. Karetova, E. Prescott, Hamdy Soliman, Ants Paapstel, Kimmo Makinen, Slavco Tosev, E. Messas, Z. Pagava, Oliver J. Müller, K. Naka, Z. Járai, T. Gudjonsson, Michael Jonas, Salvatore Novo, P. Ibrahimi, O. Lunegova, V. Dzērve, Nerijus Misonis, Jean Beissel, E. Pllaha, Mustapha Taberkant, Torbjørn Bakken, R. Teles, D. Lighezan, A. Konradi, M. Zavatta, J. Madaric, Z. Fras, L. S. Melchor, Ulf Näslund, Beatrice R. Amann‐Vesti, Agu Obiekezie   +105 more
semanticscholar   +1 more source

Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification

FEBS Open Bio, EarlyView.
Chronic kidney disease (CKD) patients often suffer from intestinal and/or mineral and bone disorders. Using a rat model, we showed that uremic vascular calcification is associated with gut barrier alterations (decreased gut mucus production and Nlrp6 gene expression, increased gut inflammation), and plasma retention of gut‐origin uremic toxins (indoxyl
Piotr Bartochowski, Irene Cortijo, Shruti Bhargava, Bernard Jover, Fabrice Raynaud, Juliana H Boukhaled, Anne‐Dominique Lajoix, Vera Jankowski, Joachim Jankowski, Magali Cordaillat‐Simmons, Àngel Argilés, Nathalie Gayrard, Flore Duranton, Jonas Laget   +13 more
wiley   +1 more source