Results 131 to 140 of about 11,970,410 (409)

MicroRNAs in Vascular Biology and Vascular Disease [PDF]

Journal of Cardiovascular Translational Research, 2010
MicroRNAs (miRNAs) have emerged as a novel class of endogenous, small, non-coding RNAs that negatively regulate over 30% of genes in a cell via degradation or translational inhibition of their target mRNAs. Functionally, an individual miRNA is important as a transcription factor because it is able to regulate the expression of its multiple target genes.
openaire   +2 more sources

The incidence and risk factors for new onset atrial fibrillation in the PROSPER study [PDF]

, 2011
Aims Atrial fibrillation/flutter (AF) is the most common arrhythmia in older people. It associates with reduced exercise capacity, increased risk of stroke, and mortality. We aimed to determine retrospectively whether pravastatin reduces the incidence of
B. Buckley, Benjamin, Benjamin, D. J. Stott, Go, Grimsmo, H. Murray, Haywood, I. Ford, J. Shepherd, J. W. Jukema, Liakopoulos, Liu, N. Sattar, P. W. Macfarlane, R. G. J. Westendorp, Romhilt, Schnabel, Shepherd, Shepherd, Young-Xu   +20 more
core   +1 more source

Constructing an early warning model for elderly sepsis patients based on machine learning

Scientific Reports
Sepsis is a serious threat to human life. Early prediction of high-risk populations for sepsis is necessary especially in elderly patients. Artificial intelligence shows benefits in early warning.
Xuejie Ma, Yaoqiong Mai, Yin Ma, Xiaowei Ma   +3 more
doaj   +1 more source

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

FEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji, Hae Sung Lee, Haesung Lee, Jong‐Hee Kim   +3 more
wiley   +1 more source

Hyperhomocysteinemia: an independent risk factor for vascular disease.

New England Journal of Medicine, 1991
BACKGROUND Hyperhomocysteinemia arising from impaired methionine metabolism, probably usually due to a deficiency of cystathionine beta-synthase, is associated with premature cerebral, peripheral, and possibly coronary vascular disease. Both the strength
R. Clarke, L. Daly, K. Robinson, E. Naughten, S. Cahalane, B. Fowler, I. Graham   +6 more
semanticscholar   +1 more source

The role of circular RNAs in regulating cytokine signaling in cancer

FEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi, Swati, Amit Mishra, Amaresh Panda, Vivek Sharma   +4 more
wiley   +1 more source

Long-term outcomes of omniflow II biosynthetic vascular graft in lower extremity arterial revascularization [PDF]

, 2018
Background: This study aims to evaluate the patency rates and long-term outcomes of femoro-popliteal bypass procedures with Omniflow II biosynthetic vascular grafts in patients with occlusive vascular disease.
Göncü, M.T., Toktaş, F., Yavuz, Ş., Çayır, Mustafa Çağdaş, Özsin, K.K.   +4 more
core   +1 more source

A Rare Case of Exophiala Dermatitidis Isolation in a Patient with Non-Cystic Fibrosis Bronchiectasis: Colonization or True Infection?

Diagnostics
Background: Exophiala dermatitidis is a dematiaceous, thermotolerant, yeast-like fungus increasingly recognized as an opportunistic pathogen in chronic airway diseases.
Francesco Rocco Bertuccio, Nicola Baio, Simone Montini, Valentina Ferroni, Vittorio Chino, Lucrezia Pisanu, Marianna Russo, Ilaria Giana, Elisabetta Gallo, Lorenzo Arlando, Klodjana Mucaj, Mitela Tafa, Maria Arminio, Emanuela De Stefano, Alessandro Cascina, Angelo Guido Corsico, Giulia Maria Stella, Valentina Conio   +17 more
doaj   +1 more source

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source

A British Medical Association Lecture ON PROGNOSIS IN CARDIO-VASCULAR DISEASE [PDF]

, 1924
T. F. Cotton
openalex   +1 more source