Results 141 to 150 of about 10,950,819 (369)

Metabolic Consequences of Rheumatoid Arthritis

open access: yesArthritis Care &Research, EarlyView.
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry   +2 more
wiley   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

open access: yesAdvanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi   +4 more
wiley   +1 more source

Novel Biomarkers in Evaluating Cardiac Function in Patients on Hemodialysis—A Pilot Prospective Observational Cohort Study

open access: yesDiagnostics
Chronic kidney disease patients treated by hemodialysis present a high cardiovascular morbidity and mortality. There is an imperative need for novel biomarkers for identifying these patients and to offer possible therapeutically interventions.
Lazar Chisavu   +7 more
doaj   +1 more source

Research Progress of Lung Cancer with Leptomeningeal Metastasis

open access: yesChinese Journal of Lung Cancer, 2014
Leptomeningeal metastases is one of the most serious complications of lung cancer, the patients with poor prognosis. Leptomeningeal metastasis in patients with lack specificity of clinical manifestations.
Chunhua MA   +5 more
doaj   +1 more source

Murine Models and Human Cell Line Models to Study Altered Dynamics of Ovarian Follicles in Polycystic Ovary Syndrome

open access: yesAdvanced Biology, EarlyView.
The manuscript examines preclinical murine and human models to study polycystic ovary syndrome (PCOS), delving into the cellular and molecular mechanisms underlying altered ovarian follicular dynamics. It explores the cellular interactions involved in normal and PCOS ovaries and outlines the current and novel strategies in the search for preclinical ...
Arturo Bevilacqua   +5 more
wiley   +1 more source

Use of the Archimedes navigation system to diagnose peripheral pulmonary lesions: preliminary Italian results

open access: yesFrontiers in Oncology
Diagnosis of peripheral pulmonary lesions (PPL) is one of the most challenging fields in early lung cancer diagnosis. Despite novel techniques and new approaches to the periphery of the lung, almost 25% of PPL remains undiagnosed.
Filippo Lanfranchi   +4 more
doaj   +1 more source

Robust semi-automatic vessel tracing in the human retinal image by an instance segmentation neural network [PDF]

open access: yesarXiv
The morphology and hierarchy of the vascular systems are essential for perfusion in supporting metabolism. In human retina, one of the most energy-demanding organs, retinal circulation nourishes the entire inner retina by an intricate vasculature emerging and remerging at the optic nerve head (ONH). Thus, tracing the vascular branching from ONH through
arxiv  

Extracorporeal Catalytic Hemoperfusion Therapy for Refractory Septic Shock Using Ceria Nanoparticle‐Embedded Porous Microbeads

open access: yesAdvanced Functional Materials, EarlyView.
This study introduces an extracorporeal hemoperfusion system incorporating porous microbeads embedded with autocatalytic ceria nanoparticles (CeNPs) for targeted reactive oxygen species (ROS) scavenging in septic shock. The blood‐compatible hemoperfusion cartridge demonstrated significant improvements in survival, hemodynamic stability, and organ ...
Pilseon Im   +10 more
wiley   +1 more source

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