Results 21 to 30 of about 18,690 (216)

MicroRNAs in Vascular Biology and Vascular Disease [PDF]

Journal of Cardiovascular Translational Research, 2010
MicroRNAs (miRNAs) have emerged as a novel class of endogenous, small, non-coding RNAs that negatively regulate over 30% of genes in a cell via degradation or translational inhibition of their target mRNAs. Functionally, an individual miRNA is important as a transcription factor because it is able to regulate the expression of its multiple target genes.
openaire   +2 more sources

Hypoglycemia and Vascular Disease [PDF]

Clinical Chemistry, 2011
Macrovascular and microvascular complications commonly occur in individuals with type 1 and type 2 diabetes. The mechanisms responsible for these complications remain the subjects of intense investigation. With regard to atherosclerosis specifically, there have been great strides in describing the pathophysiological connection between alterations in ...
Lisa M, Younk, Stephen N, Davis
openaire   +2 more sources

Development and validation of a prediction model to estimate risk of acute pulmonary embolism in deep vein thrombosis patients

Scientific Reports, 2022
Venous thromboembolism (VTE), clinically presenting as deep vein thrombosis (DVT) or pulmonary embolism (PE). Not all DVT patients carry the same risk of developing acute pulmonary embolism (APE).
You Li, Yuncong He, Yan Meng, Bowen Fu, Shuanglong Xue, Mengyang Kang, Zhenzhen Duan, Yan Chen, Yifan Wang, Hongyan Tian   +9 more
doaj   +1 more source

Vascular Teams in Peripheral Vascular Disease

Journal of the American College of Cardiology, 2019
Peripheral vascular disease affects millions of individuals worldwide, and results in significant morbidity and mortality. The complex nature of the disease, the presence of multiple comorbidities, and the existence of a wide variety of therapeutic options suggests that a multidisciplinary approach to treatment has the potential to improve care of ...
Dhaval, Kolte, Sahil A, Parikh, Gregory, Piazza, Mehdi H, Shishehbor, Joshua A, Beckman, Christopher J, White, Michael R, Jaff, Alexander, Iribarne, Tom C, Nguyen, James B, Froehlich, Kenneth, Rosenfield, Herbert D, Aronow   +11 more
openaire   +2 more sources

Risk scoring system to predict contrast induced nephropathy following percutaneous coronary intervention

Indian Heart Journal, 2014
Background: Contrast induced nephropathy (CIN) is associated with significant morbidity and mortality after percutaneous coronary intervention (PCI).
Suma M. Victor, Anand Gnanaraj, VijayaKumar S., Rajendra Deshmukh, Mani Kandasamy, Ezhilan Janakiraman, Ulhas M. Pandurangi, K. Latchumanadhas, Georgi Abraham, Ajit S. Mullasari   +9 more
doaj   +1 more source

Treatment with direct oral anticoagulants in patients with upper extremity deep vein thrombosis

Thrombosis Journal, 2017
Background Upper extremity deep vein thrombosis (UEDVT) constitutes around 10% of all DVT, and can cause both pulmonary embolism (PE) and postthrombotic syndrome (PTS) in the arm.
Francisco Sánchez Montiel, Raein Ghazvinian, Anders Gottsäter, Johan Elf   +3 more
doaj   +1 more source

RhoGTPase in Vascular Disease [PDF]

Cells, 2019
Ras-homologous (Rho)A/Rho-kinase pathway plays an essential role in many cellular functions, including contraction, motility, proliferation, and apoptosis, inflammation, and its excessive activity induces oxidative stress and promotes the development of cardiovascular diseases.
Derek Strassheim, Evgenia Gerasimovskaya, David Irwin, Edward C. Dempsey, Kurt Stenmark, Vijaya Karoor   +5 more
openaire   +3 more sources

The controversy on chronic cerebrospinal venous insufficiency

Veins and Lymphatics, 2013
The objective of this review is to analyze the actual scientific controversy on chronic cerebrospinal venous insufficiency (CCSVI) and its association with both neurodegenerative disorders and multiple sclerosis (MS).
Paolo Zamboni, Erica Menegatti, Savino Occhionorelli, Fabrizio Salvi   +3 more
doaj   +1 more source

Apoptosis in Vascular Disease

European Journal of Vascular and Endovascular Surgery, 2001
densation and the formation of membrane-bound Since the original morphological description of apovesicles called apoptotic bodies. These are phagoptosis many molecular mechanisms that characterise cytosed by adjacent cells and macrophages without the apoptotic pathway have been identified. Apoptosis inducing an inflammatory response. In contrast, necis
Sykes, T.C.F., Morris, A.G., Bradbury, A.W., Mosquera, D.   +3 more
openaire   +2 more sources

Predictors of short-term outcomes in patients undergoing percutaneous coronary intervention in cardiogenic shock complicating STEMI—A tertiary care center experience

Indian Heart Journal, 2018
Background: Studying the outcomes in patients presenting with cardiogenic shock with ST-segment elevation myocardial infarction (CS-STEMI) and undergoing primary or rescue percutaneous coronary intervention (PCI) may give an insight to the unmet needs in
Deep Chandh Raja, Aashish Chopra, Vijayakumar Subban, Rashmi Maharajan, Harini Anandhan, Nandhakumar Vasu, Jawahar Farook, Ramachandran Paramasivam, Srinivasan Narayanan, Kalaichelvan Uthayakumaran, Balaji Pakshirajan, Suma Victor, Ramkumar Solirajaram, Jaishankar Krishnamoorthy, Ezhilan Janakiraman, Ulhas M. Pandurangi, Latchumanadhas Kalidoss, Ajit Sankaradas Mullasari   +17 more
doaj   +1 more source