Annals of Gastroenterological Surgery, EarlyView.The key to unlocking ICI benefit in pMMR/MSS LARC is to convert “cold” tumors into “hot” ones through lymphocyte‐sparing SCRT and judicious chemotherapy, creating a milieu in which ICIs can act effectively. ABSTRACT The management of locally advanced rectal cancer (LARC) has evolved with the adoption of total neoadjuvant therapy (TNT), integrated ...
Yoshinori Kagawa +5 more
wiley +1 more source
Are There Any Differences in the Healing Capacity between the Medial Collateral Ligament's (MCL) Proximal and Distal Parts in the Human Knee? Quantitative and Immunohistochemical Analysis of CD34, α-Smooth Muscle Actin (α-SMA), and Vascular Endothelial Growth Factor (VEGF) Expression Regarding the Epiligament (EL) Theory. [PDF]
BiomedicinesGeorgiev GP +12 more
europepmc +1 more source
Annals of Gastroenterological Surgery, EarlyView.Sequential hepatic vein embolization (HVE) following portal vein embolization (PVE) significantly improves both the volume and function of the future remnant liver (FRL) compared to PVE alone. In this study, the FRL regeneration rates for volume and function were markedly higher and faster in the PVE–HVE group, with no differences in surgical outcomes ...
Thanh Tung Lai +9 more
wiley +1 more source
Statement of Retraction: F-box and WD repeat domain-containing 7 (FBXW7) mediates the hypoxia inducible factor-1α (HIF-1α)/vascular endothelial growth factor (VEGF) signaling pathway to affect hypoxic-ischemic brain damage in neonatal rats. [PDF]
Bioengineeredeuropepmc +1 more source
Related searches:
Vascular endothelial growth factors VEGF‐B and VEGF‐C
Journal of Cellular Physiology, 1997Vascular endothelial growth factor, which was idenheart cDNA library, respectively, by using a serendipitously found partial mouse cDNA clone as a probe tified almost 10 years ago, has so far been considered as the only growth factor relatively specific for endothelial (20,24).
V, Joukov +7 more
openaire +2 more sources
Vascular Endothelial Growth Factor (VEGF) Expression in Plasmacytoma
Leukemia & Lymphoma, 2002Vascular endothelial growth factor (VEGF) plays an important role in angiogenesis. Although the role and importance of angiogenic factors such as VEGF have been established in various solid tumors, this has not been widely evaluated in hemopoietic neoplasias.
Paydas S. +3 more
openaire +2 more sources
Vascular Endothelial Growth Factor (VEGF) in Autoimmune Diseases
Journal of Clinical Immunology, 2007Vascular endothelial growth factor (VEGF) is a potent stimulating factor for angiogenesis and vascular permeability. There are eight isoforms with different and sometimes overlapping functions. The mechanisms of action are under investigation with emerging insights into overlapping pathways and cross-talk between other receptors such as the neuropilins,
Jozélio Freire, Carvalho +2 more
openaire +2 more sources
Vascular endothelial growth factor (VEGF) and its receptors
The FASEB Journal, 1999ABSTRACT Vascular endothelial growth factor (VEGF) is a highly specific mitogen for vascular endothelial cells. Five VEGF isoforms are generated as a result of alternative splicing from a single VEGF gene. These isoforms differ in their molecular mass and in biological properties such as their ability to bind to ...
G, Neufeld +3 more
openaire +2 more sources
Vascular Endothelial Growth Factor (VEGF)
1995Abstract VEGF purified from conditioned media of normal and neoplastic cells is a glycoprotein of -45000 kDa (Ferrara and Henzel 1989). It is inactivated by reducing agents but it is heat- and acid-stable. By alternative splicing of RNA, VEGF may exist in four different homodimeric isoforms (Leung et al. 1989; Houck et al.
N Ferrara, J E Park
openaire +1 more source