Results 61 to 70 of about 94,381 (312)

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source

Arteriovenous fistula as a complication of transradial coronary angiography: a case report

Journal of Medical Case Reports, 2013
Introduction Iatrogenic arteriovenous fistula is a vascular condition that may result from coronary angiography. Many case reports have described arteriovenous fistula occurrence after coronary angiography using the transfemoral access route, but rarely ...
Dehghani Payam, Culig Jennifer, Patel Darshan, Kraushaar Greg, Schulte Paul   +4 more
doaj   +1 more source

Postoperative Stress Accelerates Atherosclerosis Through Inflammatory Remodeling of the HDL Proteome and Impaired Reverse Cholesterol Transport

Advanced Science, EarlyView.
The study shows that noncardiac surgical inflammation rapidly disrupts HDL function and cholesterol efflux in mice and human patients. Impaired reverse cholesterol transport after surgery drives rapid lipid accumulation, NETosis, and apoptosis within atherosclerotic plaques.
Dominique M. Boucher, Victoria Lorant, Valerie Rochon, Abigail Carter, Cameron Stotts, My‐Anh Nguyen, Thomas Laval, Christina Emerton, Nathan Joyce, Nysa Vinayak, Marlena Scaffidi, David Cook, Katey J. Rayner, Rebecca C. Auer, Scott M. Gordon, Mireille I. Ouimet   +15 more
wiley   +1 more source

Dysfunction of the arteriovenous fistula for hemodialysis as a consequence of venous neointimal hyperplasia and treatment strategies [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2019
One of the main problems related to inadequate planning of vascular access is dysfunction during maturation. Arteriovenous fistula dysfunction is most often a consequence of neointimal hyperplasia.
Stolić Radojica
doaj   +1 more source

Advances in imaging chest tuberculosis: blurring of differences between children and adults [PDF]

, 2009
This article reviews the ongoing role of imaging in the diagnosis of tuberculosis (TB) and its complications. A modern imaging classification of TB, taking into account both adults and children and the blurring of differences in the presentation patterns,
Ahmad, Al-Nasser, Andronikou, Andronikou, Andronikou, Andronikou, Andronikou, Bosch-Marcet, Bosch-Marcet, Buckingham, Burrill, Casas, Conces, De Backer, De Backer, De Villiers, den Boon, du Plessis, Erlank, Erlank, Fraser, Glicklich, Goodman, Goussard, Griffith-Richards, Grobbelaar, Gulati, Hamilton, Haramati, Hartman, Hopewell, Im, Jeong, Kim, Kim, Lee, Lee, Leung, Lighter, Marais, Maydell, Moon, Morris, Nakanishi, Neufang, Perlman, Raviglione, Reid, Rodriguez, Santelli, Scheepers, Stead, Swingler, Theron, Van Dyck, Van Rie, Vanhoenacker, Verver, Verver, Wall, Westcott, Woodring, Yilmaz, Zellweger   +63 more
core   +2 more sources

Vascular fistulas of the brain and spinal cord

Neurosurgical Focus, 2012
Vascular fistulas of the brain and spinal cord are among the most challenging conditions that neurosurgeons encounter. The evolution of venous drainage that causes dynamic changes in pathophysiology accounts for their highly variable natural history.
Arun Paul, Amar, David W, Newell
openaire   +2 more sources

Mechanostimulatory Cues Determine Intestinal Fibroblast Fate and Profibrotic Remodeling in a Physiodynamic Human Gut‐on‐a‐Chip

Advanced Science, EarlyView.
A healthy gut barrier shields underlying fibroblasts from luminal shear forces, illustrating that “good fences make good neighbors.” Barrier damage exposes fibroblasts to shear stress, inducing cell death and the emergence of stress‐adapted, profibrotic fibroblasts. Sustained shear exposure promotes the formation of stiff aggregates of mechanoadapative
Soyoun Min, Nam Than, Yong Cheol Shin, Elif G. Ertugral, Chandrasekhar R. Kothapalli, Olumuyiwa Awoniyi, Hyun Jung Kim   +6 more
wiley   +1 more source

Arterial-portal fistula treated with hepatic arterial embolization and portal venous aneurysm stent-graft exclusion complicated by type 2 endoleak. [PDF]

, 2019
Intrahepatic arterioportal fistulas may be complicated by portal hypertension. An associated portal venous aneurysm (PVA) may impinge upon adjacent structures or rupture.
Bremer, William A, Bui, James T, Gaba, Ron C, Lokken, R Peter   +3 more
core  

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source

Immediate access arteriovenous grafts versus tunnelled central venous catheters: study protocol for a randomised controlled trial [PDF]

, 2015
Background Autologous arteriovenous fistulae (AVF) are the optimal form of vascular access for haemodialysis. AVFs typically require 6 to 8 weeks to “mature” from the time of surgery before they can be cannulated.
Aitken, Emma, Berry, Colin, Chandramohan, Mohan, Geddes, Colin, Kasthuri, Ram, Kingsmore, David, Thomson, Peter   +6 more
core   +2 more sources