Results 11 to 20 of about 82,561 (299)

Anti-Sca-1 antibody-functionalized vascular grafts improve vascular regeneration via selective capture of endogenous vascular stem/progenitor cells

Bioactive Materials, 2022
Small-diameter vascular grafts fabricated from synthetic biodegradable polymers exhibit beneficial mechanical properties but often face poor regenerative potential. Different tissue engineering approaches have been employed to improve tissue regeneration
He Wang, Mengmeng Xing, Weiliang Deng, Meng Qian, Fei Wang, Kai Wang, Adam C. Midgley, Qiang Zhao   +7 more
doaj   +2 more sources

BIOMECHANICAL REMODELING OF BIODEGRADABLE SMALL-DIAMETER VASCULAR GRAFTS IN SITU

Вестник трансплантологии и искусственных органов, 2016
Aim: to evaluate the biomechanical remodeling of polymer grafts modified with vascular endothelial growth factor (VEGF) after implantation into rat abdominal aorta.Materials and methods.
T. V. Glushkova, V. V. Sevostyanova, L. V. Antonova, K. Yu. Klyshnikov, E. A. Ovcharenko, E. A. Sergeeva, G. Yu. Vasyukov, A. M. Seifalian, L. S. Barbarash   +8 more
doaj   +3 more sources

Results of preclinical trials in a sheep model of biodegradable small-diameter vascular grafts

Вестник трансплантологии и искусственных органов, 2022
Surface modification of polymer vascular matrices is a promising development for preventing vascular graft thrombosis, improving long-term patency and accelerating remodeling. Objective: to study the outcomes of long-term patency of PHBV/PCL/GFmix grafts
L. V. Antonova, E. O. Krivkina, M. Yu. Khanova, E. A. Velikanova, V. G. Matveeva, А. V. Mironov, A. R. Shabaev, Е. A. Senokosova, T. V. Glushkova, M. Yu. Sinitsky, R. А. Mukhamadiyarov, L. S. Barbarash   +11 more
doaj   +1 more source

Strategies to counteract adverse remodeling of vascular graft: A 3D view of current graft innovations

Frontiers in Bioengineering and Biotechnology, 2023
Vascular grafts are widely used for vascular surgeries, to bypass a diseased artery or function as a vascular access for hemodialysis. Bioengineered or tissue-engineered vascular grafts have long been envisioned to take the place of bioinert synthetic ...
Wei Tan, Parnaz Boodagh, Prakash Parthiban Selvakumar, Sean Keyser   +3 more
doaj   +1 more source

Surface modification of decellularized bovine carotid arteries with human vascular cells significantly reduces their thrombogenicity

Journal of Biological Engineering, 2021
Background Since autologous veins are unavailable when needed in more than 20% of cases in vascular surgery, the production of personalized biological vascular grafts for implantation has become crucial.
Eriselda Keshi, Peter Tang, Marie Weinhart, Hannah Everwien, Simon Moosburner, Nicolai Seiffert, Michael Lommel, Ulrich Kertzscher, Brigitta Globke, Anja Reutzel-Selke, Benjamin Strücker, Johann Pratschke, Igor Maximillian Sauer, Nils Haep, Karl Herbert Hillebrandt   +14 more
doaj   +1 more source

The Regulatory Effect of Braided Silk Fiber Skeletons with Differential Porosities on In Vivo Vascular Tissue Regeneration and Long-Term Patency

Research, 2022
The development of small-diameter vascular grafts that can meet the long-term patency required for implementation in clinical practice presents a key challenge to the research field.
Xili Ding, Weirong Zhang, Peng Xu, Wentao Feng, Xiaokai Tang, Xianda Yang, Lizhen Wang, Linhao Li, Yan Huang, Jing Ji, Diansheng Chen, Haifeng Liu, Yubo Fan   +12 more
doaj   +1 more source

Tissue-engineered small-diameter vascular grafts containing novel copper-doped bioactive glass biomaterials to promote angiogenic activity and endothelial regeneration

Materials Today Bio, 2023
Small-diameter vascular grafts frequently fail because of obstruction and infection. Despite the wide range of commercially available vascular grafts, the anatomical uniqueness of defect sites demands patient-specific designs. This study aims to increase
Neda Alasvand, Aliasghar Behnamghader, Peiman B. Milan, Sara Simorgh, Ali Mobasheri, Masoud Mozafari   +5 more
doaj   +1 more source

The application of tissue-engineered fish swim bladder vascular graft

Communications Biology, 2021
Bai et al. employ a fish bladder-derived decellularized matrix for the engineering of vascular grafts. The authors show that rapamycin-coated bladder-derived vascular grafts can be implanted as an interposition graft in rats, and that these vascular ...
Hualong Bai, Peng Sun, Haoliang Wu, Shunbo Wei, Boao Xie, Wang Wang, Yachen Hou, Jing’an Li, Alan Dardik, Zhuo Li   +9 more
doaj   +1 more source

Evaluation of small-diameter silk vascular grafts implanted in dogsCentral MessagePerspective

JTCVS Open, 2021
Objectives: Vascular replacement is one treatment for cardiovascular disease. However, in blood vessels with a diameter less than 6 mm, the existing artificial vascular grafts may be occluded by thrombus formation or intimal hyperplasia.
Takashi Tanaka, DVM, PhD, Ryo Tanaka, DVM, PhD, Yoko Ogawa, BS, Yoshihide Takagi, BS, Masataka Sata, MD, PhD, Tetsuo Asakura, PhD   +5 more
doaj   +1 more source

Development and in vivo validation of tissue-engineered, small-diameter vascular grafts from decellularized aortae of fetal pigs and canine vascular endothelial cells

Journal of Cardiothoracic Surgery, 2017
Background Tissue engineering has emerged as a promising alternative for small-diameter vascular grafts. The aim of this study was to determine the feasibility of using decellularized aortae of fetal pigs (DAFPs) to construct tissue-engineered, small ...
Xu Ma, Zhijuan He, Ling Li, Guofeng Liu, Qingchun Li, Daping Yang, Yingbo Zhang, Ning Li   +7 more
doaj   +1 more source