Results 51 to 60 of about 129,720 (304)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Use of vascular clips to approximate skin grafts on the burned hand

Burns Open, 2018
Background: Burns of the hands are common and can lead to significant functional and aesthetic impairment. Traditionally, sutures or staples are used to approximate adjacent skin grafts on the hand; however, we have found that vascular clips are a ...
Rachael M. Payne, Luis Quiroga, Carisa M. Cooney, Julie A. Caffrey   +3 more
doaj   +1 more source

Gene Transfer of Calcitonin Gene-Related Peptide Inhibits Macrophages and Inflammatory Mediators in Vein Graft Disease [PDF]

, 2008
Vein graft disease is a chronic inflammatory disease and limits the late results of coronary revascularization. Calcitonin gene-related peptide (CGRP) inhibits macrophages infiltrated and inflammatory mediators, we hypothesized that transfected CGRP gene
Hongsui Wu, Huanxin Yang, Jian Su, Jian Zhuang, Jianguang Chen, Shiliang Chen, Xiaoning Zhang, Yuhui Zheng, Zhihong Chen   +8 more
core   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

INFLUENCE OF bFGF, SDF-1α, OR VEGF INCORPORATED INTO TUBULAR POLYMER SCAFFOLDS ON THE FORMATION OF SMALL-DIAMETER TISSUE-ENGINEERED BLOOD VESSEL IN VIVO

Вестник трансплантологии и искусственных органов, 2018
Aim. To evaluate the potential synergistic effects of basic fi broblast growth factor (bFGF) and stromal cell-derived factor-1α (SDF-1α) complemented with VEGF compared to VEGF alone when being added into poly(3-hydroxybutyrateco-3-hydroxyvalerate ...
L. V. Antonova, V. V. Sevostyanova, A. G. Kutikhin, Е. A. Velikanova, V. G. Matveeva, T. V. Glushkova, A. V. Mironov, E. O. Krivkina, O. L. Barbarash, L. S. Barbarash   +9 more
doaj   +1 more source

Immediate access arteriovenous grafts versus tunnelled central venous catheters: study protocol for a randomised controlled trial [PDF]

, 2015
Background Autologous arteriovenous fistulae (AVF) are the optimal form of vascular access for haemodialysis. AVFs typically require 6 to 8 weeks to “mature” from the time of surgery before they can be cannulated.
Aitken, Emma, Berry, Colin, Chandramohan, Mohan, Geddes, Colin, Kasthuri, Ram, Kingsmore, David, Thomson, Peter   +6 more
core   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Comparison of Multifurcated and Composite Vascular Grafts for Abdominal Aortic Aneurysms with Iliac Arterial Lesions

Indian Journal of Vascular and Endovascular Surgery, 2017
Introduction: Reconstructing the internal iliac artery (IIA) may help to prevent pelvic ischemia during open repair of abdominal aortic aneurysms (AAAs) with iliac arterial lesions.
Akimasa Morisaki, Mitsuharu Hosono, Takashi Murakami, Masanori Sakaguchi, Shinsuke Nishimura, Toshihiko Shibata   +5 more
doaj   +1 more source

Corrugated nanofiber tissue-engineered vascular graft to prevent kinking for arteriovenous shunts in an ovine model

JVS - Vascular Science, 2020
Objective: Prosthetic grafts are often needed in open vascular procedures. However, the smaller diameter prosthetic grafts (
Hiroshi Matsushita, MD, Takahiro Inoue, MD, PhD, Sara Abdollahi, PhD, Enoch Yeung, MBBS, Chin Siang Ong, MBBS, PhD, Cecillia Lui, MD, Isaree Pitaktong, Kevin Nelson, PhD, Jed Johnson, PhD, Narutoshi Hibino, MD, PhD   +9 more
doaj   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source