Results 61 to 70 of about 2,003,281 (347)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Use of vascular clips to approximate skin grafts on the burned hand

Burns Open, 2018
Background: Burns of the hands are common and can lead to significant functional and aesthetic impairment. Traditionally, sutures or staples are used to approximate adjacent skin grafts on the hand; however, we have found that vascular clips are a ...
Rachael M. Payne, Luis Quiroga, Carisa M. Cooney, Julie A. Caffrey   +3 more
doaj   +1 more source

Rapid fabrication of reinforced and cell-laden vascular grafts structurally inspired by human coronary arteries

Nature Communications, 2019
Design strategies for small diameter vascular grafts are converging toward native-inspired tissue engineered grafts. A new automated technology is presented that combines a dip-spinning methodology for depositioning concentric cell-laden hydrogel layers,
Tamara L. Akentjew, Claudia Terraza, Cristian Suazo, Jekaterina Maksimcuka, Camila A. Wilkens, Francisco Vargas, G. Zavala, Macarena Ocaña, J. Enrione, Claudio M. García-Herrera, Loreto M. Valenzuela, J. Blaker, Maroun Khoury, J. Acevedo   +13 more
semanticscholar   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

INFLUENCE OF bFGF, SDF-1α, OR VEGF INCORPORATED INTO TUBULAR POLYMER SCAFFOLDS ON THE FORMATION OF SMALL-DIAMETER TISSUE-ENGINEERED BLOOD VESSEL IN VIVO

Вестник трансплантологии и искусственных органов, 2018
Aim. To evaluate the potential synergistic effects of basic fi broblast growth factor (bFGF) and stromal cell-derived factor-1α (SDF-1α) complemented with VEGF compared to VEGF alone when being added into poly(3-hydroxybutyrateco-3-hydroxyvalerate ...
L. V. Antonova, V. V. Sevostyanova, A. G. Kutikhin, Е. A. Velikanova, V. G. Matveeva, T. V. Glushkova, A. V. Mironov, E. O. Krivkina, O. L. Barbarash, L. S. Barbarash   +9 more
doaj   +1 more source

Intestinal transplantation in composite visceral grafts or alone [PDF]

, 1992
Under FK 506-based immunosuppression, the entire cadaver small bowel except for a few proximal and distal centimeters was translated to 17 randomly matched patients, of whom two had antigraft cytotoxic antibodies (positive cross-match).
Abu-Elmagd, K, Busuttil, RW, Casavilla, A, Demetris, AJ, Fung, JJ, Nakamura, K, Nour, BM, Rapaport, FT, Reyes, J, Selby, R, Shaw, BW, Starzl, TE, Thompson, JC, Todo, S, Tzakis, AG, Van Thiel, DH, Vasconez, LO, Wright, H   +17 more
core   +1 more source

Small Caliber Compliant Vascular Grafts Based on Elastin-Like Recombinamers for in situ Tissue Engineering

Frontiers in Bioengineering and Biotechnology, 2019
Vascular disease is a leading cause of death worldwide, but surgical options are restricted by the limited availability of autologous vessels, and the suboptimal performance of prosthetic vascular grafts. This is especially evident for coronary artery by-
A. Fernández‐Colino, Frederic Wolf, S. Rütten, T. Schmitz-Rode, J. Rodríguez‐Cabello, S. Jockenhoevel, P. Mela   +6 more
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Comparison of Multifurcated and Composite Vascular Grafts for Abdominal Aortic Aneurysms with Iliac Arterial Lesions

Indian Journal of Vascular and Endovascular Surgery, 2017
Introduction: Reconstructing the internal iliac artery (IIA) may help to prevent pelvic ischemia during open repair of abdominal aortic aneurysms (AAAs) with iliac arterial lesions.
Akimasa Morisaki, Mitsuharu Hosono, Takashi Murakami, Masanori Sakaguchi, Shinsuke Nishimura, Toshihiko Shibata   +5 more
doaj   +1 more source

Corrugated nanofiber tissue-engineered vascular graft to prevent kinking for arteriovenous shunts in an ovine model

JVS - Vascular Science, 2020
Objective: Prosthetic grafts are often needed in open vascular procedures. However, the smaller diameter prosthetic grafts (
Hiroshi Matsushita, MD, Takahiro Inoue, MD, PhD, Sara Abdollahi, PhD, Enoch Yeung, MBBS, Chin Siang Ong, MBBS, PhD, Cecillia Lui, MD, Isaree Pitaktong, Kevin Nelson, PhD, Jed Johnson, PhD, Narutoshi Hibino, MD, PhD   +9 more
doaj   +1 more source