Results 111 to 120 of about 4,437,433 (360)

The IkB kinase inhibitor nuclear factor-kB essential modulator–binding domain peptide for inhibition of balloon injury-induced neointimal formation [PDF]

, 2009
Objective—The activation of nuclear factor-kB (NF-kB) is a crucial step in the arterial wall’s response to injury. The identification and characterization of the NF-kB essential modulator– binding domain (NBD) peptide, which can block the activation of
Carnuccio, R., De Stefano, D., Di Lauro, M.V., Di Meglio, P., Grassia, G., Ialenti, A., Ianaro, A., Kennedy, S., Maddaluno, M., Maffia, P., Musilli, C., Parenti, A., Parratt, C.A.   +12 more
core   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Complex vascular injury in a case of multiple gunshot wounds in a combat zone

Indian Journal of Vascular and Endovascular Surgery, 2018
Abdominal vascular injuries are the most common cause of early death after penetrating abdominal trauma if especially associated with a chest injury and fracture of long bones.
Vivek Agrawal, Dhananjay Singh, Sandeep Mehrotra, Varinder Bedi   +3 more
doaj   +1 more source

Inhibition of miR-92a improves re-endothelialization and prevents neointima formation following vascular injury

Cardiovascular Research, 2014
Aims MicroRNA (miR)-92a is an important regulator of endothelial proliferation and angiogenesis after ischaemia, but the effects of miR-92a on re-endothelialization and neointimal lesion formation after vascular injury remain elusive.
J. Daniel, Daniela Penzkofer, R. Teske, J. Dutzmann, Alexander Koch, W. Bielenberg, A. Bonauer, R. Boon, A. Fischer, J. Bauersachs, E. van Rooij, S. Dimmeler, D. Sedding   +12 more
semanticscholar   +1 more source

Clinical Validation of Plasma p‐217tau in Neurological Diseases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi, Takumi Nakamura, Ryoma Takahashi, Tetsuya Ueda, Seiji Kinoshita, Chikage Uchida, Takashi Sugawara, Kentaro Hashimoto, Kunihiko Ishizawa, Masakuni Amari, Hiroo Kasahara, Yoshio Ikeda, Masamitsu Takatama, Mikio Shoji   +13 more
wiley   +1 more source

Tanshinone IIA accelerates zebrafish venous vascular repair via macrophage recruitment through the CXCR4A–CXCL12B signaling axis

Frontiers in Immunology
BackgroundVascular injury is a major contributor to the development of cardiovascular diseases. Following vascular damage, macrophages migrate to the injury site and, during the later stages of vascular repair, secrete cytokines such as interleukin-10 ...
Li Zhang, Li Zhang, Lijuan An, Lijuan An, Yanchi Zhao, Yanchi Zhao, Zheng Lu, Zheng Lu, Jiangtao Huang, Jiangtao Huang, Lingling Tang, Lingling Tang, Mengzhu Lv, Mengzhu Lv, Dashuang Mo, Dashuang Mo, Liping Shu, Liping Shu   +17 more
doaj   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

Interferon regulatory factor 9 is critical for neointima formation following vascular injury

Nature Communications, 2014
Interferon regulatory factor 9 (IRF9) has various biological functions and regulates cell survival; however, its role in vascular biology has not been explored.
Shumin Zhang, Lihua Zhu, Houzao Chen, Ran Zhang, Peng Zhang, D. Jiang, Lu Gao, S. Tian, Lang Wang, Yan Zhang, Pi-xiao Wang, Xiao-fei Zhang, Xiao-dong Zhang, De-Pei Liu, Hongliang Li   +14 more
semanticscholar   +1 more source

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu, Xiaoning Ren, Cuihua Fan, Chun Li, Lijie Zhang, Zaiqiang Zhang, Shaowu Li, Zhongmeng Lai, Bin Cai, Ying Fu, Yi Lin, Zhibao Zhu   +11 more
wiley   +1 more source

Novel long noncoding lncARF mediated hyperhomocysteinemia-induced atherosclerosis via autophagy inhibition in foam cells

Journal of Advanced Research
Introduction: Homocysteine (Hcy) is well recognized to be an independent risk factor for atherosclerosis. Long non-coding RNAs (lncRNAs) are emerging regulators of pathophysiological processes including atherosclerosis, while the underlying mechanisms of
Ning Ding, Shengchao Ma, Qingning Chang, Lin Xie, Guizhong Li, Yinju Hao, Jiantuan Xiong, Anning Yang, Xiaoling Yang, Yideng Jiang, Huiping Zhang   +10 more
doaj   +1 more source