Results 151 to 160 of about 72,747 (294)

Strategic Design of Soft Actuators in Translational Medical Robotics for Human‐Centered Healthcare

Advanced Robotics Research, EarlyView.
Soft robotics enables biocompatible, compliant medical devices, but clinical translation requires design‐driven engineering beyond materials. This perspective reviews implantable, surgical, and wearable systems by actuation mechanism, highlighting how optimized architectures and integration improve mechanical interfacing, adaptability, and durability ...
Ho Jun Jin, Jimin Kim, Inho Kim, Bong Hoon Kim   +3 more
wiley   +1 more source

ELABELA Targets Mitochondria to Modulate Heart Development

Advanced Science, EarlyView.
The role of peptide ELABELA (ELA) in cardiomyocyte apoptosis and congenital heart disease (CHD) is unclear. ELA deficiency caused cardiomyocyte apoptosis and CHD. A novel ELA‐APJ‐AKT‐BCL2/BAX axis in regulating mitochondrial function and contributing to CHD pathogenesis was established.
Jian Wang, Qingjie Wang, Zhikang Xu, Shuang Zhou, Yue Zhou, Junjie Yang, Lingfeng Tong, Zhuo Meng, Mei Yang, Wen Zhao, Tie Yang, Hualin Wang, Jun Zhang, Rubin Tan, Lei Wang, Yuqiang Huang, Bin Zhou, Sun Chen, Bing Zhang, Jinxiang Yuan, Jianyuan Zhao, Alex F. Chen, Kun Sun   +22 more
wiley   +1 more source

Effectiveness and Safety of Bleomycin Electrosclerotherapy for Slow-Flow Vascular Malformations: A Systematic Review. [PDF]

Cardiovasc Intervent Radiol
Gehr J, Hindsø L, Taudorf M, Eiberg JP, Frevert SC, Jensen RJ, Kaltoft M, Lönn LB, de la Motte LR, Strøm M, Clausen C.   +10 more
europepmc   +1 more source

Biology of vascular malformations of the brain

, 2009
BACKGROUND AND PURPOSE: This review discusses recent research on the genetic, molecular, cellular, and developmental mechanisms underlying the etiology of vascular malformations of the brain (VMBs), including cerebral cavernous malformation, sporadic ...
Keep RF, Connolly SE Jr, Ball KL, Gunel M, Mohr JP, Zhang J., Plahn BK, Marchuk D, Ning M, Awad IA, Gale NW, Nishimura S, Faurobert E, Jin K, Lo EH, Rigamonti D, Li DY, Leblanc GG, Morrison L, Shenkar R, Letarte M, Stapf C, Chopp M, Tournier Lasserve E, Biology of Vascular Malformations of the Brain NINDS Workshop Collaborators:Awad I, McCarty J, Johnson GL, Kim H, Pratt WB, Plate KH, Lee C, Hashimoto T, Blasig IE, Golanov E, NOONAN, DOUGLAS, Pratt CA, Clancy MS, Yang GY, Berg M, Al Shahi Salman R, Pawlikowska L, Hannegan L, Spatz M, Derry B, Boudreau N, Gault J, Oh SP, Ginsberg M, Young WL, Lawton MT, Nunn MF   +50 more
core  

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

Advanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao, Hang Liu, Yanfeng Yao, Wei Deng, Jiawen Sun, Zhenyu Kang, Ashaq Ali, Chao Shan, Zhiming Yuan, Fei Deng, Hualin Wang, Yun‐Jia Ning   +11 more
wiley   +1 more source

Complications of Pregnancy and Birth in Women With Vascular Malformations: A Nationwide Cross-Sectional Study. [PDF]

BJOG
de Oliveira Marreiros DJ, Lokhorst MM, Horbach SER, Stor MLE, van Hout N, Gerdes VEA, Ganzevoort W, van der Horst CMAM.   +7 more
europepmc   +1 more source

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

DOT1L Drives Endothelial‐to‐Mesenchymal Transition and Fibrotic Vascular Remodeling via H3K79 Methylation

Advanced Science, EarlyView.
DOT1L as a central epigenetic regulator of EndoMT and pulmonary fibrosis. Acting as an early epigenetic switch, it translates TGFβ–SMAD signaling into H3K79me2‐mediated chromatin remodeling, selectively activates fibrosis‐related genes, and primes ECs for rapid mesenchymal transition.
Yaofeng Wang, Xing Peng, Jingjing Chen, Yun Zhang, Tinghong Zhang, Jingyuan Zhang, Jiaying Fan, Hui Zheng, Qiaoyuan Liu, Zhimin Song, Zhan‐Peng Huang, Shu Meng   +11 more
wiley   +1 more source

Profile of AV Malformations - An Experience of Tertiary Care Centre

JK Science
Background: AV malformations are aberrations in the development of vessels with varied presentations that may lead to aesthetic, limb and life-threatening complications.
Mohit Arora, Arvind Kohli, I. A. Mir, Shyam Singh   +3 more
doaj  

Vascular malformations of the head and neck and a molecularly guided precision therapy framework. [PDF]

Front Neurol
Qu HQ, Li D, Hakonarson H.
europepmc   +1 more source