Results 11 to 20 of about 112,494 (240)

Research progress on targeted drugs for vascular malformations

口腔疾病防治, 2023
Vascular malformations, which mainly occur in the head and neck region, are a group of congenital disorders that cannot involute and dilate gradually as patients grow.
SHEN Yuchen , WANG Deming, FAN Xindong
doaj   +1 more source

Sirolimus Early Treatment in Vascular Anomalies Leads to a Better Response

Journal of Vascular Anomalies, 2023
Objectives:. Sirolimus has become a relevant drug in the treatment of vascular anomalies, initially relegated to rescue therapy for refractory lesions but more recently has become first line.
Paloma Triana, Jesús Díez-Sebastián, Lara Rodriguez-Laguna, Victor Martinez-Glez, Juan Carlos Lopez-Gutierrez   +4 more
doaj   +1 more source

Children Treated for Slow-flow Vascular Malformations: Overall Description and Focus on Complications Such as Cellulitis. [PDF]

Acta Derm Venereol
Bredy S, Coronas E, Degrugillier-Chopinet C, Cailliau E, Catteau B, Dubos F.   +5 more
europepmc   +3 more sources

Vascular Birthmarks as a Clue for Complex and Syndromic Vascular Anomalies

Frontiers in Pediatrics, 2021
Vascular birthmarks are common in neonates (prevalence: 20–30%) and mostly incidental findings sometimes with spontaneous regression (salmon patch and nevus simplex). Capillary malformations are found in about 1% and infantile hemangiomas are found in 4%
Andrea Diociaiuti, Guglielmo Paolantonio, Mario Zama, Rita Alaggio, Claudia Carnevale, Andrea Conforti, Claudia Cesario, Maria Lisa Dentici, Paola Sabrina Buonuomo, Massimo Rollo, May El Hachem   +10 more
doaj   +1 more source

Ischaemic strokes in patients with pulmonary arteriovenous malformations and hereditary hemorrhagic telangiectasia: associations with iron deficiency and platelets. [PDF]

, 2014
BackgroundPulmonary first pass filtration of particles marginally exceeding ∼7 µm (the size of a red blood cell) is used routinely in diagnostics, and allows cellular aggregates forming or entering the circulation in the preceding cardiac cycle to lodge ...
AD Kjeldsen, AD Kjeldsen, AE Guttmacher, AJ Easey, B Barzilai, B Nieswandt, Basel Chamali, BD Butler, BJ Folz, BM Silva, C Coupland, C Shovlin, CJ Gallione, CL Shovlin, CL Shovlin, CL Shovlin, CL Shovlin, CL Shovlin, CL Shovlin, CL Shovlin, CL Shovlin, Claire L. Shovlin, DW Johnson, E Buscarini, ER Chilvers, ER Weibel, F Roked, Gillian Angus, H Finnamore, Hannah C. Tighe, HL Devlin, IS Anand, J Feinstein, J Parra, J Remy, JA Dutton, JA Feinstein, JA Livesey, James E. Jackson, JE Van de Pette, JJ Mager, JL Hart, John A. Livesey, John Meek, K Clark, K Hara, K Nanthakumar, K Ono, K Zukotynski, KL Furie, Klaus Brusgaard, LC Weng, LS Valberg, M Bajc, M Billinger, M Blomley, M Moussouttas, M Nakayama, M Yeung, ME Faughnan, Michael A. Laffan, MK Whyte, MW van Gent, MW van Gent, OS AAssar, P Gazzaniga, P Gupta, P Shovlin CL, Wilmshurst, PC Hébert, RD Thompson, RF Gillum, Richard Manning, S Jackson, S Uchiyama, S Velthuis, SM Bang, T Krings, T Ueki, V Cottin, Vatshalan Santhirapala, WB Porter, Y Benjamini, Y Shinohara, Z Hao   +83 more
core   +4 more sources

Arterial dysgenesis and limb defects : Clinical and experimental examples [PDF]

, 2017
Acknowledgements This article is dedicated to Dr David S. Packard Jr. With thanks to Dr John DeSesso, Dr Lewis B. Holmes, Dr Mark Levinsohn, Dr David S.
Hootnick, David R., Vargesson, Neil
core   +1 more source

Exceptional aggressiveness of cerebral cavernous malformation disease associated with PDCD10 mutations. [PDF]

, 2015
PurposeThe phenotypic manifestations of cerebral cavernous malformation disease caused by rare PDCD10 mutations have not been systematically examined, and a mechanistic link to Rho kinase-mediated hyperpermeability, a potential therapeutic target, has ...
Akers, Amy L, Austin, Cecilia, Awad, Issam A, De Souza, Jorge Marcondes, Gallione, Carol J, Gunel, Murat, Lee, Connie, Marchuk, Douglas A, McDonald, David A, Mikati, Abdul Ghani, Min, Wang, Rebeiz, Tania, Rorrer, Autumn, Shenkar, Robert, Shi, Changbin, Stockton, Rebecca A, Zhang, Lingjiao   +16 more
core   +2 more sources

Mechanochemical and surgical ablation of an anomalous upper extremity marginal vein in CLOVES syndrome identifies PIK3CA as the culprit gene mutation

Journal of Vascular Surgery Cases and Innovative Techniques, 2020
Anomalous marginal veins of the trunk or extremities are congenitally incompetent entities found in association with phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA)-related overgrowth syndromes, such as Klippel-Trénaunay ...
Young Lim, PhD, Arash Fereydooni, MD, MS, Anand Brahmandam, MD, Alan Dardik, MD, PhD, Keith Choate, MD, PhD, Naiem Nassiri, MD   +5 more
doaj   +1 more source

A Case Report and Overview of Familial Cerebral Cavernous Malformation Pathogenesis in an Adult Patient [PDF]

, 2018
OBJECTIVE We present a case of a 39 year-old woman who presented with a solitary cavernous malformation hemorrhage without any other lesions, and subsequently presented several months later with a new hemorrhage from a de novo lesion.
Arul, BS, Manu K., Gooch, MD, Michael R., Khanna, Omaditya   +2 more
core   +2 more sources

Primary lymphedema French National Diagnosis and Care Protocol (PNDS; Protocole National de Diagnostic et de Soins)

Orphanet Journal of Rare Diseases, 2021
Primary lymphedema is a rare chronic pathology associated with constitutional abnormalities of the lymphatic system. The objective of this French National Diagnosis and Care Protocol (Protocole National de Diagnostic et de Soins; PNDS), based on a ...
Stéphane Vignes, Juliette Albuisson, Laurence Champion, Joël Constans, Valérie Tauveron, Julie Malloizel, Isabelle Quéré, Laura Simon, Maria Arrault, Patrick Trévidic, Philippe Azria, Annabel Maruani, French National Referral Center for Primary Lymphedema   +12 more
doaj   +1 more source