Results 251 to 260 of about 112,593 (339)

NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction

Advanced Science, EarlyView.
NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu, Jing Luo, Li Yu, Daoxi Qi, Boyu Li, Yating Chen, Chen Wang, Xiaokang Zhang, Wenzheng Guo, Qiyong Lou, Gang Zhai, Yonglin Ruan, Jianfei Huang, Shengchi Shi, Zhan Yin, Fang Zheng   +15 more
wiley   +1 more source

Targeted therapies for vascular malformations. [PDF]

Front Med (Lausanne)
Kane G, Fernandez-Pineda I.
europepmc   +1 more source

Biocatalytic Nanoregulators Restore Joint Redox‐Immune Homeostasis in Rheumatoid Arthritis

Advanced Science, EarlyView.
Mesenchymal stem cell‐derived extracellular vesicles (EVs) coat ruthenium‐loaded metal‐organic frameworks (Ru@ZrMOF), creating a targeted therapeutic (Ru@ZrMOF/EVs). This platform scavenges ROS, generates oxygen, and polarizes macrophages from M1 to M2, alleviating inflammation, inhibiting pannus, promoting cartilage repair, and downregulating HIF‐1α ...
Xingheng Wang, Jianbo Huang, Shuwei Zhang, Sujiao Cao, Fangxue Du, Liqiang Zhou, Li Qiu, Yuanjiao Tang   +7 more
wiley   +1 more source

4D flow MRI for noninvasive monitoring of high-flow vascular malformations in neonates and infants: A feasibility study. [PDF]

Interv Neuroradiol
Massachi JA, Yoo C, Walia S, Schollenberger J, Saloner D, Kim H, Fox CK, Fullerton HJ, Hetts SW, Narsinh KH.   +9 more
europepmc   +1 more source

Vascular Malformations of the Orofacial Region

, 2011
Zena Patel, Santosh Gupta
openalex   +1 more source

A Patient‐Derived Organ‐on‐Chip Platform for Modeling the Tumor Microenvironment and Drug Responses in Pancreatic Cancer

Advanced Science, EarlyView.
Researchers have developed a patient‐derived organ‐on‐a‐chip model for pancreatic cancer by integrating cancer cells with supportive stromal and immune cells inside a microfluidic device. This system mimics the tumor microenvironment, enabling personalized testing of chemotherapy and immunotherapy, and offering new insights into how targeting ...
Darbaz Adnan, Natan Roberto de Barros, Luca S. Santovito, Xuhong Cheng, Kristi M. Lawrence, Mariah K. Barnett, Martine D. Boetto, Neal Mehta, Ajaypal Singh, Lin Cheng, Xiangsheng Huang, Faraz Bishehsari   +11 more
wiley   +1 more source

Stochastic Nanoscale Biophysical Cues as a Basis for the Induction of Glioblastoma‐Like Transcriptional Programs in Astrocytes

Advanced Science, EarlyView.
Stochastic nanoscale physical cues induce glioblastoma (GBM)‐associated transcriptional traits in naïve astrocytes leading to spontaneous formation of spheroids. Cells within spheroids express activated‐MMP2 and a differential gene expression pattern involving P53 and NOTCH3, providing evidence for a role for changes in brain topography, as observed in
Laurent Starck, Tobias Butelmann, Sabrina Hogan, Melika Sarem, Bernd Heimrich, Ritwick Sawarkar, Marie‐Françoise Ritz, Gregor Hutter, V. Prasad Shastri   +8 more
wiley   +1 more source

Personalized sirolimus regimen for vascular malformations: a retrospective analysis of VASE cohort

Seront E, Damme AV, Coulie J, Vikkula M, Boon LM.   +4 more
europepmc   +1 more source

Embryological cellular origins and hypoxia-mediated mechanisms in PIK3CA-driven refractory vascular malformations. [PDF]

EMBO Mol Med
Torii S, Nagaharu K, Nakanishi N, Usui H, Hori Y, Hirose K, Toyosawa S, Morii E, Narushima M, Kubota Y, Nakagawa O, Imanaka-Yoshida K, Maruyama K.   +12 more
europepmc   +1 more source

Dendritic fibromyxolipoma with intramuscular involvement: A case mimicking slow flow vascular malformation on imaging

Hashim AlSalman, Hassan Alsayegh, Nada Elmukhtar, Ahmad Alzahrani, Salman S. Albakheet, Qasem AlAlwan, Ahmed Almuslim, Haniyya AlRehaily, Mohammed Al Salman   +8 more
openalex   +1 more source