Results 61 to 70 of about 404,221 (259)

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Midterm Outcomes of Extra-anatomical Subcutaneous Posteromedial Arterial Bypass in Around-Knee Neoplasms [PDF]

Ain-Shams Journal of Surgery
Introduction: Around-knee neoplasms with vascular involvement pose a significant surgical challenge. Traditionalin-line arterial reconstructions following tumor excision are associated with high complication and reinterventionrates, particularly in ...
Mina Basta, Yasser Barakat, Hamdy AboElNeel   +2 more
doaj   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Deceptive Mass - Intramuscular Hemangioma in the Chest Wall: A Case Report

Annals of Medicine and Medical Sciences
Intramuscular hemangiomas (IMHs) are rare, benign vascular tumours accounting for less than 1% of all hemangiomas. Chest wall IMHs are even rarer. Here, we report a case of a 16-year-old male who presented with a progressively enlarging, painless mass in
Dr Akshay Gupta
doaj  

Adrenal Castleman's Disease Mimicking Other Adrenal Neoplasms: A Case Report

대한영상의학회지, 2017
We present a rare case of adrenal Castleman's disease with hyaline vascular type mimicking other adrenal neoplasms in a 65-year-old woman. Although rare, the hyaline vascular type of adrenal Castleman's disease should be included in the differential ...
Seung Baek Hong, Nam Kyung Lee, Suk Kim, Ga Jin Han, Hong Koo Ha, Ja Yoon Ku, Sang Jeong Ahn, Chang Hun Lee   +7 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Masson’s Tumor Mimicking Mesenchymal Neoplasia: A Case Report of Intravascular Papillary Endothelial Hyperplasia in the Deltoid Muscle

Case Reports in Oncology
Introduction: Intravascular papillary endothelial hyperplasia (IPEH), or Masson’s tumor, is a benign endothelial proliferation that typically arises in soft tissues and lacks cytological atypia.
Cristina Peralta Rivera, Miguel Ángel Monroy Ramírez, Diana Ximena Morán Bernal, Camila Dennys Arteaga González, Saúl Iván Gómez López, Saided Solano Vargas, Rafael Silva Flores   +6 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Assessment of the survival rate of patients with malignant neoplasms of the choroid in the Orenburg region

Российский офтальмологический журнал
The purpose of the work is to analyze the impact of various factors on the survival of patients with malignant neoplasms of the choroid.Materials and methods. A retrospective analysis of the databases of the V.I.
A. E. Aprelev, D. N. Begun, I. I. Zakirova, S. A. Shmitkova   +3 more
doaj   +1 more source