Results 181 to 190 of about 3,425,425 (249)

Gm26550 Modulates Learning and Memory by Increasing IGF1 mRNA Expression and Stability in Nrf2−/− Mice

Advanced Science, EarlyView.
The present study shows that Nrf2 directly binds to the Gm26550 promoter, thereby activating Gm26550 transcription and increasing its expression. Mechanistically, Gm26550 promotes IGF1 expression by functionally antagonizing miR‐26a‐5p‐mediated repression and sequestering the RBP KHSRP, thereby enhancing hippocampal neuronal synaptic plasticity and ...
Hongfang Wang, Ziyao Wang, Dongyue Zuo, Zhaowen Su, Bowen Song, Jiamin Gao, Yizhou Zhang, Ruiting Zhao, Linjie Sun, Mengdi Li, Yirui Fan, Dandan Geng, Lei Wang   +12 more
wiley   +1 more source

Commentary: Advances in Diagnosis and Management of Hemodynamic Instability in Neonatal Shock

Frontiers in Pediatrics, 2018
David J. R. Hutchon
doaj   +1 more source

Noninvasive Estimation of Pulmonary Vascular Resistance Using Right Ventricular Outflow Doppler Analysis. [PDF]

JACC Adv
Afonso L, Ala CK, Sood A, Adegbala O, Kahe F, Dawdy J, Bell K, Bahar AR, Blank N.   +8 more
europepmc   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Impella preserves haemodynamics with adequate stressed blood volume and normal pulmonary vascular resistance in a goat model of ventricular fibrillation. [PDF]

Eur Heart J Open
Yokota S, Maruhashi T, Kakuuchi M, Nishikawa T, Matsushita H, Morita H, Sato K, Yoshida Y, Kawada T, Uemura K, Nishinaka T, Saku K.   +11 more
europepmc   +1 more source

Functional Disorder at the Neural Interface: How Disordered Nanostructures Promote Proper Growth and Differentiation in In Vitro Neural Cultures

Advanced Science, EarlyView.
This work provides a practical guide for neuroengineers to design advanced neural interfaces, embracing and tailoring the concept of functional disorder. By bridging 2D and 3D in vitro models, this work highlights how non‐periodic, spatially heterogeneous, multiscale nanotopography can enable more physiologically relevant platforms for studying neural ...
F. Maita, E. Palmieri, I. Lucarini, L. Montaina, L. Maiolo   +4 more
wiley   +1 more source

The dynamic interplay between endothelial reactivity, temperature, and vascular resistance in cardiopulmonary bypass. [PDF]

Ann Med Surg (Lond)
Condello I, Federico M, Condello S.
europepmc   +1 more source

Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants

Advanced Science, EarlyView.
The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann, Laura M. De Santis, Paul Neering, Christian Boehler, Kirti Sharma, Arno Aarts, Tobias Holzhammer, Rik J. J. van Daal, Patrick Ruther, Maria Asplund, Roxana N. Kooijmans, Pieter R. Roelfsema   +11 more
wiley   +1 more source

Placental Vascular Resistance and Offspring Growth From Birth to Age 2 Years.

JAMA Netw Open
Xu L, Zhang J, Chen K, Dong X, Qin X, Huang M, Kong D, Fan X, Mu X, Hu L, Wang Y, Xia Z, Li J, Zhou A, Xiong C.   +14 more
europepmc   +1 more source

Effect of trunk upward verticalization on pulmonary vascular resistance in ARDS. [PDF]

Crit Care
Benites MH, Retamal J.
europepmc   +1 more source