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Engineering Complexity: Advances in 3D Breast Cancer Models for Precision Oncology
In vitro breast cancer models that closely mimic the complex biological and cellular interactions within the tumor microenvironment hold strong promise for enhancing our understanding of tumor progression, immune system behavior, and resistance to therapies, which are essential for developing personalized cancer treatments. Abstract Engineered in vitro
Wonwoo Jeong, Sang Jin Lee
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AI‐Assisted Design and Evaluation of SLM‐Ti64 Implants for Enhanced Bone Regeneration
AI‐driven simulations of biological healing, combining biomechanical modeling and machine learning, enable personalized orthopedic treatments. By decoding healing patterns influenced by implants and patient‐specific factors, this approach advances fracture repair understanding, optimizes implant design, and supports precision medicine and sustainable ...
Muhammad Usama Zaheer +3 more
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Elevated pulmonary vascular resistance is associated with increased lung transplant waitlist mortality among patients with chronic obstructive pulmonary disease and pulmonary hypertension: a retrospective cohort analysis. [PDF]
Gayen SK, Zulty M, Criner GJ.
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Pulmonary vascular resistance [PDF]
Almost 20 years ago, Adriaan Versprille published an editorial in this journal to explain why, in his opinion, the calculation of pulmonary vascular resistance (PVR) is meaningless [1]. The uncertainties of PVR were underscored a year later by McGregor and Sniderman in the American Journal of Cardiology [2]. Obviously, both papers failed to convince. A
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Pulmonary vascular resistance and vascular transmural gradient
Journal of Applied Physiology, 1960Perfusion studies were made on vascular beds of isolated dog lungs. Submerged, gas-free, fluid-distended lobes served for studies of resistance versus transmural pressure in a technique that abolished gravitational effects. Air-distended lobes with varying degrees of pulmonary edema were used to display the transmural gradient differences produced by ...
George W. Wright, Thomas C. Lloyd
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