Results 81 to 90 of about 3,425,425 (249)

Embolia arterial periférica por projétil de arma de fogo em civis: diagnóstico confirmado pelo ultrassom vascular Peripheral arterial emboli due to bullet projectile: diagnosis confirmed by vascular ultrasound [PDF]

open access: yes, 2012
Descrevemos um caso de oclusão arterial aguda por projétil de arma de fogo. Devido à raridade do caso (23 relatos em 20 anos) e a importância do diagnóstico diferencial precoce, uma revisão bibliográfica foi realizada.
Silvestre, José Manuel Silva   +17 more
core   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

Analysis of Pulse Wave Morphology Measured by Photoplethysmography During Arm Position Changes

open access: yesJournal of Biomedical Photonics & Engineering
Numerous studies underscore the importance of analyzing pulse wave morphology via photoplethysmography (PPG) as an accessible method for investigating localized vascular responses.
Anatoly V. Skripal   +6 more
doaj   +1 more source

Inflammation, insulin resistance, and diabetes : mendelian randomization using CRP haplotypes points upstream [PDF]

open access: yes, 2008
Background Raised C-reactive protein (CRP) is a risk factor for type 2 diabetes. According to the Mendelian randomization method, the association is likely to be causal if genetic variants that affect CRP level are associated with markers of diabetes ...
Timpson, NJ   +95 more
core   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Doppler Ultrasound Indices of the Major Arteries as Markers of Vascular Tone during Thermal Stress

open access: yesJournal of Biomedical Photonics & Engineering
This study focuses on the effects of moderate thermal heating on microcirculation and peripheral hemodynamics, as well as on the interrelationship between changes detected by Laser Doppler Flowmetry (LDF) and Ultrasound Doppler (USD).
Anatoly V. Skripal   +3 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Patient-Specific Computational Fluid Dynamics of Pulmonary Arterial Hemodynamics in Dogs with and Without Pulmonic Stenosis

open access: yesAnimals
Pulmonic stenosis (PS) is one of the most common congenital cardiac diseases in dogs. Although echocardiography and computed tomographic angiography (CTA) provide valuable diagnostic and anatomical information, the hemodynamic consequences of PS remain ...
Carla Zamora-Perarnau   +3 more
doaj   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk   +10 more
wiley   +1 more source

Primary Role of the Kidney in Pathogenesis of Hypertension

open access: yesLife
Previous transplantation studies and the concept of ‘nephron underdosing’ support the idea that the kidney plays a crucial role in the development of essential hypertension.
Gheun-Ho Kim
doaj   +1 more source

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