Results 291 to 300 of about 2,596,890 (367)

Development of a Modular Ribonucleoprotein Complex as a General Strategy to Deliver RNAi Therapeutics

Advanced Healthcare Materials, EarlyView.
A modular and customizable RNAi therapeutics delivery platform composed of a pseudosymmetric human RNA binding protein‐siRNA complex (SmiRNP) is developed. By fusing a targeting module and an endosomal escape peptide onto the delivery platform, SmiRNP successfully delivered siRNA to silence the KRAS oncogene in a colorectal carcinoma cell line, leading
Nok Yin Tam, Xiaoqi Wang, Grace Chung Yan Chan, Wai Po Kong, Wai Yin Chau, Xiuqiong Fu, Kwok‐Yin Wong, Hong Lok Lung, Zhi‐Ling Yu, Wei Shen Aik   +9 more
wiley   +1 more source

Design and performance verification of a novel vascular anastomosis connector. [PDF]

Sci Rep
Lai F, Cao C, Zou W, Li Y, Liu W, Qiu Z, Chen L.   +6 more
europepmc   +1 more source

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Congenital vascular ring

Surgery Today, 2019
A vascular ring is a rare congenital cardiovascular anomaly, which encircles and compresses the trachea or esophagus, or both. In this review we discuss the pathophysiology, theoretical embryopathogenesis, diagnostic modalities, and surgical treatment of the different types of vascular ring.
Naoki Yoshimura, Masaya Aoki, Takahiro Homma, Yuki Ikeno, Shigeki Yokoyama, Kanetsugu Nagao, Akihiko Higashida, Toshio Doi, Akio Yamashita, Yoshifumi Shimada, Shigeyuki Yamashita, Kazuaki Fukahara, Daisuke Toritsuka   +12 more
openaire   +4 more sources

Assessment of children with vascular ring

Pediatrics International, 2016
AbstractBackgroundVascular rings may cause pressure on the trachea and/or esophagus of varying degree, resulting in symptoms. This study assessed the presentation symptoms, diagnostic methods and treatment results after surgery in children with vascular ring.MethodsSymptomatic vascular ring patients undergoing surgery between January 2010 and August ...
Aysel Türkvatan, Hasan Tahsin Tola, Okan Yildiz, Sertaç Haydin, Yakup Ergül, Alper Güzeltaş, Erkut Öztürk, Ihsan Bakir, Ersin Erek   +8 more
openaire   +4 more sources

Congenital Aortic Vascular Ring

Archives of Surgery, 1969
Compression of the trachea and esophagus by vascular anomalies of the aortic arch and its branches may be a threat to life in infancy. The significance of the so-called vascular ring, long recognized as a cause of obstruction of the trachea and esophagus in early life, assumed new importance in 1945 when the operation by Gross 1 placed this entity ...
George G. Lindesmith, Bernard L. Tucker, Quentin R. Stiles, Bert W. Meyer, John C. Jones   +4 more
openaire   +4 more sources

Vascular rings

Seminars in Pediatric Surgery, 2021
Vascular rings are congenital aortic arch anomalies that lead to compression of the trachea or esophagus. The goal of this review is to summarize our current recommendations for the management of patients with a diagnosis of a vascular ring. We review the history, classification methods, and epidemiology of the various types of vascular rings.
David J, Worhunsky, Brittany E, Levy, Elizabeth H, Stephens, Carl L, Backer   +3 more
openaire   +2 more sources

Vascular ring anomalies in cats: 20 cases (2000-2018).

Veterinary surgery, 2020
OBJECTIVE To report the clinical characteristics, types of vascular ring anomalies (VRA), operative findings, complications, and survival after surgical treatment of cats with VRA. STUDY DESIGN Retrospective, multi-institutional case series.
A. Bascuñán, Penny J. Regier, J. B. Case, Ameet Singh, Ingrid M Balsa, J. Flanders, K. Thieman-Mankin, Kathleen M. Ham   +7 more
semanticscholar   +1 more source

Morphology of vascular ring arch anomalies influences prognosis and management

Archives of Disease in Childhood, 2020
Objective This study aimed to explore the anatomical features of aortic arch anomalies associated with vascular rings, hoping to identify those which may increase the risk of symptomatic presentation and surgical intervention.
Elena Ctori, A. Crucean, B. Pinkey, S. Mcguirk, Robert H. Anderson, J. Stickley, T. Jones, A. Seale   +7 more
semanticscholar   +1 more source