Results 31 to 40 of about 1,560,986 (269)

Feline megaesophagus associated with persistence of the right aortic arch [PDF]

Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Vascular ring anomalies are conditions that can be diagnosed in cats, although their frequency is lower than that in dogs. The fourth aortic arch is a condition characterized by the presence of a vascular ring that obstructs the physiological passage of ...
A.P. Silva, F.G. Sousa, C.A.P. Perdigão, A.C.C. Fonseca, S.L. Beier   +4 more
doaj   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Descending aortic translocation for aerodigestive vascular compression

JTCVS Open
Objective: Patients with complex vascular ring anomalies can present with symptoms of esophageal and airway compression, occasionally persisting despite relief of the vascular ring, due to residual compression from the aorta.
Sarah Tsou, MD, Peter Chiu, MD, Ryan Benavente, BS, Daniel Castellanos, MD, Jennifer Brown, PA-C, Lianne Cole, MSN, CPNP, Benjamin Zendejas, MD, Christopher W. Baird, MD   +7 more
doaj   +1 more source

Right-sided Aortic Arch with Aberrant Left Subclavian Artery Arising from a Kommerell Diverticulum: A Case Report [PDF]

Journal of Clinical and Diagnostic Research
Right-sided aortic arch with an Aberrant Left Subclavian Artery (ALSA) arising from a Kommerell diverticulum is a rare congenital anomaly of the aortic arch system.
Ankit Gandhi, Shashank M Hiremath, Aditya Hadole, Asif Tamboli, Amol Bhoite   +4 more
doaj   +1 more source

Identifying Patterns of Hospitalizations Among Childhood Cancer Survivors: A Population‐Based Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood cancer survivors (CCSs) experience more hospitalizations than the general population. We aimed to identify distinct hospitalization patterns among Queensland CCSs and the associated characteristics. Methods Cases (aged ≤14 years) diagnosed between 1995 and 2019 while residents of Queensland were identified through the ...
Hai Pham, Teyl Engstrom, Peter Baade, Natalie Bradford, Sarah Pont, Louise Marquart‐Wilson, Natasha Nassar, Jason D. Pole   +7 more
wiley   +1 more source

Left thoracoscopic two-stage repair of tracheoesophageal fistula with a right aortic arch and a vascular ring

Journal of Minimal Access Surgery, 2017
A right aortic arch (RAA) is found in 5% of neonates with tracheoesophageal fistulae (TEF) and may be associated with vascular rings. Oesophageal repairs for TEF with an RAA via the right chest often pose surgical difficulties.
Kazuo Oshima, Hiroo Uchida, Takahisa Tainaka, Akihide Tanano, Chiyoe Shirota, Kazuki Yokota, Naruhiko Murase, Ryo Shirotsuki, Kosuke Chiba, Akinari Hinoki   +9 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Anomalous origin of the left brachiocephalic artery in the right aortic arch: Is there a method to the madness?

Annals of Pediatric Cardiology, 2017
The anomalous origin of the left brachiocephalic artery in a right sided aortic arch is a rare vascular ring which might lead to esophageal compression. The exact embryological origin of this anomaly is still widely debated.
Mani Ram Krishna, Ganesh Kumar Gnanappa, Rachel Fitzpatrick, Julian Ayer, David Winlaw   +4 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Undiagnosed Double Aortic Arch in an Adult With Repaired Tetralogy of Fallot

JACC: Case Reports, 2019
Double aortic arch, the most common vascular ring, causes a complete ring surrounding the esophagus and trachea that leads to compressive symptoms. This report describes a young woman with a history of totally corrected tetralogy of Fallot who was a ...
Anita Sadeghpour, MD, Nakisa Khansari, MD, Marziyeh Pakbaz, MD, Kiara Rezaei Kalantari, MD, Hamidreza Pouraliakbar, MD, Maziar Gholampour Dehaki, MD   +5 more
doaj   +1 more source