Results 161 to 170 of about 2,851,022 (307)

Single‐Cell Transcriptomic Analysis of Tumor Heterogeneity and the Microenvironment in Pseudomyxoma Peritonei

open access: yesAdvanced Science, EarlyView.
This study presents a single‐cell atlas of pseudomyxoma peritonei spanning primary and paired metastatic lesions. Distinct epithelial substates, stromal remodeling, immune exclusion, lipid metabolic reprogramming, and a candidate angiogenic network were identified in metastatic lesions.
Xi Li   +14 more
wiley   +1 more source

Targeting Different Lesion Locations in Lower Extremity Atherosclerotic Disease: Insights From Cardiovascular Risk Factor Profiling

open access: yesJournal of Interventional Cardiology
Wenzhuo Meng   +12 more
doaj   +1 more source

Considerações sobre o uso de enoxaparina genérica em síndrome coronariana aguda

open access: yesArquivos Brasileiros de Cardiologia, 2010
Marise Gomes   +3 more
doaj   +1 more source

Nivolumab Plus Lenvatinib and Intra-Arterial Locoregional Therapy as First-Line Treatment for Unresectable Hepatocellular Carcinoma: A Real-World Study

open access: yesJournal of Hepatocellular Carcinoma
Shanzhi Gu,1,* Yang Zhao,1,* Haixiong Yan,2 Muzi Li,2 Guowen Li,2 Manping Huang,1 Zhengping Xiong,1 Bin Huang21Department of Interventional Vascular Surgery I, Hunan Cancer Hospital, Changsha, 410000, People’s Republic of China ...
Gu S   +7 more
doaj  

Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu   +13 more
wiley   +1 more source

Guidelines for critical limb ischaemia and diabetic foot--introduction

open access: yes, 2011
Ricco J. B.   +2 more
core   +1 more source

Gm26550 Modulates Learning and Memory by Increasing IGF1 mRNA Expression and Stability in Nrf2−/− Mice

open access: yesAdvanced Science, EarlyView.
The present study shows that Nrf2 directly binds to the Gm26550 promoter, thereby activating Gm26550 transcription and increasing its expression. Mechanistically, Gm26550 promotes IGF1 expression by functionally antagonizing miR‐26a‐5p‐mediated repression and sequestering the RBP KHSRP, thereby enhancing hippocampal neuronal synaptic plasticity and ...
Hongfang Wang   +12 more
wiley   +1 more source

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