Results 41 to 50 of about 880,080 (267)

FBXO38 Regulates Nox1 Stability to Reduce Vascular Endothelial Damage Induced by Low Oscillatory Shear Stress

Cardiovascular Therapeutics
Oxidative stress and endothelial dysfunction are critical drivers of atherosclerosis, but the mechanisms regulating oxidative stress under disturbed flow conditions remain incompletely understood.
Wan-li Yu, Li-wen Deng, Huan-huan Li, Chun-kai Wang, Xiang-yi Zuo, Zi-chang Wang, Li Meng, Lan-xin Wen, Wan-zhi Zeng, Yu Zhao, Xue-hu Wang   +10 more
doaj   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Validation of the Society for Vascular Surgery's Objective Performance Goals for critical limb ischemia in everyday vascular surgery practice

, 2011
BackgroundTo develop standardized metrics for expected outcomes in lower extremity revascularization for critical limb ischemia (CLI), the Society for Vascular Surgery (SVS) has developed objective performance goals (OPGs) based on aggregate data from ...
DeMartino, Randall R., Nathanael D. Hevelone, Vascular Study Group of New England, Hevelone, Nathanael D., Philip P. Goodney, Nolan, Brian W., Jack L. Cronenwett, Conte, Michael S., Powell, Richard J., Cronenwett, Jack L., Brian W. Nolan, Schanzer, Andres, Richard J. Powell, Hevelone, Nathanael, Goodney, Philip P., Michael S. Conte, Randall R. DeMartino, Andres Schanzer   +17 more
core   +1 more source

Prospective Comparison of Wound Complication Rates after Elective Open Peripheral Vascular Surgery - Endovascular Versus Open Vascular Surgeons

, 2023
Background: Skill and experience of surgeons are likely to influence the incidence of surgical wound complications (SWC) after open lower limb revascularization.
Johan Nyman, Stefan Acosta, Christina Monsen, Hasselmann, Julien,, Nyman, Johan, Monsen, Christina,, Julien Hasselmann, Nyman, Johan,, Robert Svensson-Björk, Hasselmann, Julien, Acosta, Stefan, Svensson-Björk, Robert, Svensson-Björk, Robert,, Acosta, Stefan,, Lund University., Monsen, Christina   +15 more
core   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Vacuum-assisted wound closure versus alginate for the treatment of deep perivascular wound infections in the groin after vascular surgery

, 2014
Vacuum-assisted wound closure (VAC) therapy may heal wounds faster than conventional dressings after surgical debridement of perivascular groin infections after vascular ...
Wann-Hansson, Christine,, Acosta, Stefan,, Monsen, Christina,, Wictorsson, Catharina, Lund University.   +4 more
core   +2 more sources

Knockdown of lncRNA XIST Ameliorates IL-1β-Induced Apoptosis of HUVECs and Change of Tissue Factor Level via miR-103a-3p/HMGB1 Axis in Deep Venous Thrombosis by Regulating the ROS/NF-κB Signaling Pathway

Cardiovascular Therapeutics, 2022
Background. The effect of lncRNA X inactive-specific transcript (XIST) inducing cardiovascular diseases on deep vein thrombosis (DVT) and its mechanism has not been reported.
Guangxin Cao, Hua Zhou, Dong Wang, Lei Xu   +3 more
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Endovascular Management of a Deep Femoral Artery Perforating Branch Pseudoaneurysm after Total Hip Arthroplasty: A Case Study

Case Reports in Medicine, 2022
Pseudoaneurysm of the profundal femoris artery (PFA) following total hip arthroplasty (THA) is a rare and unusual complication. Awareness of this complication and a high level of suspicion allow early diagnosis and treatment, thereby reducing the ...
Sami Nabhani, Eric Cheysson, Pamela Sabbah, Georges Baaklini   +3 more
doaj   +1 more source