Results 91 to 100 of about 1,036,133 (364)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Variations in Surgical Procedures for Inducing Hind Limb Ischemia in Mice and the Impact of These Variations on Neovascularization Assessment

International Journal of Molecular Sciences, 2019
Mouse hind limb ischemia is the most common used preclinical model for peripheral arterial disease and critical limb ischemia. This model is used to investigate the mechanisms of neovascularization and to develop new therapeutic agents.
Z. Aref, M. D. de Vries, P. Quax
semanticscholar   +1 more source

EFFICACY OF THE ENDOVASCULAR TREATMENT OF THE THORACIC AND ABDOMINAL AORTIC ANEURYSMS IN CARTAGENA, COLOMBIA

Revista Ciencias Biomédicas, 2015
Introduction: The aortic aneurysms (AA) are a segmentary and permanent dilatation of the aorta that could end in a catastrophic outcome named acute aortic syndrome (AAS), which could curse with rupture and in most cases in death.
Marzola-Peña Katy, Arrieta-Usta Micaela
doaj  

Literature review of peripheral vascular trauma: Is the era of intervention coming?

Chinese Journal of Traumatology, 2020
Traumatic peripheral vascular injury is a significant cause of disability and death either in civilian environments or on the battlefield. Penetrating trauma and blunt trauma are the most common forms of vascular injuries.
Jian-Long Liu, Jin-Yong Li, Peng Jiang, Wei Jia, Xuan Tian, Zhi-Yuan Cheng, Yun-Xin Zhang   +6 more
doaj   +1 more source

Immediate access arteriovenous grafts versus tunnelled central venous catheters: study protocol for a randomised controlled trial [PDF]

, 2015
Background Autologous arteriovenous fistulae (AVF) are the optimal form of vascular access for haemodialysis. AVFs typically require 6 to 8 weeks to “mature” from the time of surgery before they can be cannulated.
Aitken, Emma, Berry, Colin, Chandramohan, Mohan, Geddes, Colin, Kasthuri, Ram, Kingsmore, David, Thomson, Peter   +6 more
core   +2 more sources

Minimal-invasive, video-assisted vein harvesting for cardiac and vascular surgical procedures [PDF]

European Journal of Cardio-Thoracic Surgery, 1997
Harvesting of the saphenous vein is a routine procedure in coronary and peripheral vascular surgery. It is usually performed using a continuous long skin incision. Minor complications are reported in up to 24% (hematoma, wound dehiscence, infection, pain) and major problems necessitating surgical interventions (bleeding, abscess) in less than 1%. These
J. Schöllhorn, Friedhelm Beyersdorf, Georg Lutter, Christoph Lutz, C Schlensak   +4 more
openaire   +4 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Clavicular Chondrosarcoma: A Case Report and Brief Review of the Literature

International Journal of Hematology-Oncology and Stem Cell Research, 2016
Clavicular bone tumors occur in less than 0.5 percent of bone tumors. Primary chondrosarcoma is very rare even among clavicle tumors. The main symptom is a touchable mass in 69 % of patients.
Ali Ghorbani Abdehgah, Behnam Molavi, Saeed Reza Mehrpour, Amir Reza Radmard, Mohammad Mahjori, Nasser Kamalian, Hosein Kamranzadeh   +6 more
doaj  

Surgical treatment of patients with critical ischemia of lower limbs originating from aortoiliac lesions and concomitant coronary artery disease

Патология кровообращения и кардиохирургия, 2015
The study focuses on the outcomes of surgical treatment of 236 patients with critical ischemia of lower limbs originating from aortoiliac lesions and concomitant coronary artery disease.
А. Н. Вачёв, В. В. Сухоруков, Е. А. Суркова, А. Д. Гуреев, А. В. Кругомов, Д. А. Черновалов, М. С. Михайлов   +6 more
doaj   +1 more source

Usefulness of microsurgical back‐table angioplasty for multiple hepatic arteries in living donor liver transplantation

Annals of Gastroenterological Surgery, 2020
The graft hepatic artery orifice is tiny in living donor liver transplantation, and therefore, it is more difficult to reconstruct the hepatic artery than in deceased donor liver transplantation.
Noboru Harada, Tomoharu Yoshizumi, Toshiharu Matsuura, Tomoaki Taguchi, Masaki Mori   +4 more
doaj   +1 more source