Results 91 to 100 of about 3,539,336 (257)
Outcomes Following Vascular and Endovascular Procedures Performed During the First COVID-19 Pandemic Wave [PDF]
Objective: The first COVID-19 pandemic wave was a period of reduced surgical activity and redistribution of resources to only those with late stage or critical presentations.Khallaf, Andrew I, Clothier, Annie, Charlton, Gabriella, Bosanquet, David, Mohamed, Farag S., Elhadi, Ahmed, Garnham, Andrew, Mazingi, Dennis, Zywicka, Ewa M., Mavioglu, Hayrettin L., Elkawafi, Mohamed, Yih, Chun L. P., Lim, Eunice, Mingoli, Andrea, Attwell, Lukas, Hardy, Simon C., Pasenidou, Ketino, Vo, Uyen G, Azzam, Ahmed Y., Dovell, George, Unal, Ertekin U, Martin, Emmeline A., Coughlin, Patrick A, Alwehaibi, Nasser, Joyce, Doireann P., Dhal, Bedanta S, Elkady, Ramy, Georgopoulos, Sotirios, Sivakumaran, Yogeesan, Flumignan, Ronald LG, Aitken, Sarah J, Lauren, Santiago, Fabrico, McClure, David N., Goel, Ravi R, Locker, Dafydd, Musicki, Korana, Binkhamis, Shagran, Vasudevan, Thodur M., Richards, Toby, McClure, David N, Hein, Martin, Iqbal, Kaisor, Costanza, Michael, Antoniou, George A., Davies, Emma M., Ambler, Graeme K., Saltiel, Alberto, Kyrou, Ioanna, Atkinson, Noel, Altoijry, Abdulmajeed H., Khoo, Samantha, Warren, Sarah A., Hmaid, Hytham KS, Preece, Ryan, Rolls, Alexander ES, Kandola, Sonia, Rabee, Hussein MM, Al Shakarchi, Julien, Cheng, Stephen W. K., Fitridge, Robert, Cheng, Stephen WK, Morley, Rachael L, Saha, Prakash, Tam, Siu C., Tolba, Mahmoud M. H., Nyamekye, Isaac K, Mitka, Afroditi M, BenGhatnsh, Ahmed T. S., Muller, Juanita, Iscan, Hakkı Z., Dawson, Joseph A., Ellojli, Ibrahim A., Shelmerdine, null, Dawson, Joseph A, Meecham, Lewis, Papas, Theofanis T, Khashram, Manar, Areias, Libnah L., Cohnert, Tina U., Zacà, Sergio, Benaragama, K. S., Yih, Chun LP, Benson, Ruth A, Bessias, Nikolaos, Nouh, Thamer, Lyons, Oliver TA, Dean, Anastasia, Nunag, Jose M. S., Dawkins, Claire, Nakano, Luis CU, Algasi, Abdeljawad J., Gunawansa, Nalaka, Roy, Iain N, Twine, Christopher P, Nickinson, Andrew, Rolls, Alexander E. S., Selvaraj, Christopher N., Hurndall, Katherine, Karkos, Christos D., Varley, Vincent C, Warren, Sarah A, Unal, Ertekin U., Ng, Jun Jie, Pineda, Fernando Picazo, Galloway, Richard F, AlRakaf, Reem N., Anderson Baker, Sara J, Tshomba, Yamume, Stansby, Gerry, Altabal, Mohamed, Popplewell, Matthew A., Bakoyiannis, Christos, Angiletta, Domenico, Battersby, Ruth, Tang, Robert, Duncan, Andrew, Tinelli, Giovanni, McCaslin, James, Shelmerdine, ElSanhoury, Kareem, Saratzis, Athanasios, Choong, Andrew, Nunag, Jose MS, Papazoglou, Konstantinos O., Alhumiad, Ahmed A, Machin, Matthew, Ashcroft, James, Lyons, Oliver T. A., Thomas, Jacqueline, Harrison, Gareth J, Choudhry, Asad J., Moulakakis, Konstantinos G, Popplewell, Matthew A, Zafar, Adeel S, Shalhoub, Joseph, Aziz, Omar, Hardy, Thomas J., Azzam, Ahmed Y, Scott, Emma, Fisher, Owain, Taha, Ahmed, Fowler, Amy L, Suttenwood, Helen, Tsiantoula, Paraskevi, Hitchman, Louise, Chambers, Jennifer L, Catterson, Martin, Khan, Aazeb, Muhammad, Kamel, Stavert, Bethany M, Roditis, Konstantinos, Isik, Arda, Pulli, Raffaele, Khallaf, Andrew I., Anderson Baker, Sara J., Papazoglou, Konstantinos O, Maras, Dimitris, Premnath, Sivaram, Leong, Kai W., Coleman, Chloe, Kuang, Beatrice, Chambers, Jennifer L., Chinai, Natasha, Hattam, Andrew T, Minelli, Fabrizio, Lauren, null, Stavroulakis, Konstantinos, Martin, Emmeline A, Kilby, Joseph, Mohamed, Farag S, Akkaya, Bekir B., Sudarsanam, Abhilash, Birmpili, Panagiota, Hanna, Joseph, Nyamekye, Isaac K., Taran, Dana, Alomran, Faris, Ghatwary Tantawy, Tamer MH, Algasi, Abdeljawad J, Singh, Aminder Anthony, Walsh, Stewart R., AlHamzah, Musaad, Ellojli, Ibrahim A, Blair, Robert, Abuduruk, Aseel, Mavioglu, Hayrettin L, Altoijry, Abdulmajeed H, Charalabopoulos, Alexandros, Zafar, Adeel S., Grainger, Tabitha, Al-Saadi, Nina, Khalil, Rana, Sivaharan, Ashwin, Bosanquet, David C., Tang, Alethea M, Bashar, Khalid, Msherghi, Ahmed, Ambler, Graeme K, Tierney, Sean, Ennab, Raed M, Travers, Hannah C., Elsantawy, Hazem, Luo, Xun, Aherne, Thomas M, Galloway, Richard F., Sharif, Atif, Vasudevan, Thodur M, Abdelhaliem, Amr, Tsagkos, Ioannis, Stavert, Bethany M., Fowler, Amy L., Altaf, Nishath, Mpaili, Eustratia, Hammond, Eric, Prce, Daniela, Selvaraj, Christopher N, Goh, Mingzheng A., Parr, Noala, Forsythe, Rachael O, Makar, Ragai R, Elkhafeefi, Fatimah S., Eljareh, Mohamed S., Akkaya, Bekir B, Rahman, Habibur P, Hon, Kay, Allard, Bernard, Tang, Alethea M., Wagner, Timothy, Choudhry, Asad J, Antoniou, Afroditi, Alhumiad, Ahmed A., Mitka, Afroditi M., Sapienza, Paolo, Flumignan, Ronald L. G., Coulston, James, Hassanin, Ahmed, Gan, John, Cragg, James, Wong, Jackie, Hmaid, Hytham K. S., Papas, Theofanis T., Hardy, Simon C, Leong, Kai W, Aitken, Sarah, Hattam, Andrew T., Rabee, Hussein M. M., Benaragama, KS, Singh, Gurkirat, Moulakakis, Konstantinos G., Tam, Siu C, Imray, Chris, Varley, Vincent C., Singh, Aminder A., Liu, Ju-wei N., Almeshal, Meshal, Goel, Ravi R., Silickas, Justinas, Zaki, Shady, Moore, Hayley M, Papanikolas, Michael J, Barakat, Hashem, Kakavia, Kiriaki, Paravastu, Sharath, Valdivia, Andrés Reyes, Taha, Mohamed A. H., Iscan, Hakkı Z, Somaiya, Pranav, Ulker, Berkay, Bosanquet, David C, BenGhatnsh, Ahmed TS, Darvall, Katy, Nakano, Luis C. U., Suthers, Elizabeth, Tolba, Mahmoud MH, Benson, Ruth A., Liu, Ju-wei N, Morley, Rachael L., Harrison, Gareth J., Lapolla, Pierfrancesco, Nesbitt, Craig, Walsh, Stewart R, Moore, Hayley M., Ulusoy, Serap, Cohnert, Tina U, McKevitt, Kevin, Taha, Mohamed AH, Rahman, Habibur P., Saeed, Hani, Mehta, Shreya, Nandhra, Sandip, Egan, Bridget, Tigkiropoulos, Konstantinos, Zywicka, Ewa M, Juszczak, Maciej, Eljareh, Mohamed S, Bhakthavalsalan, Resya, Aitken, Sarah J., Dhal, Bedanta S., Nicholls, Jonathan, Buga, Ion, AlRakaf, Reem N, Kakkos, Stavros, Boyle, Emily, Joyce, Doireann P, Ahmed, Hazem, Ennab, Raed M., Ghatwary Tantawy, Tamer M. H., Sica, Simona, Travers, Hannah C, Roy, Iain N., Shelmerdine, Lauren, Forsythe, Rachael O., Johnson, Adam, Edwards, Mark, Akhtar, Tasleem, Elhadi, Muhammed, Antoniou, George A, Moss, Jana-Lee, Thet, Myat S, Elsayed, Khaled, Wang, Judy, Hardy, Thomas J, Aherne, Thomas M., Chandarana, Karishma, Davies, Emma M, Dattani, Nikesh, Elkhafeefi, Fatimah S, Karkos, Christos D, Powezka, Katarzyna, Azab, Mohammed A, Gwilym, Brenig, Twine, Christopher P., Onida, Sarah, Goh, Mingzheng A, Areias, Libnah L, Bootun, Roshan, Azab, Mohammed A., Vo, Uyen G., Davies, Huw, Coughlin, Patrick A., Tarusan, Lawrence, Attia, Doaa, Altuwaijri, Talal, El Amrani, Mehdi, Elkwahad, Maysoon, Papanikolas, Michael J., Beropoulis, Efthymios, Ravintharan, Nandhini, Pond, Franklin, Singh, Aminder A, Katsogridakis, Emmanuel, Makar, Ragai R., Thet, Myat S. +353 morecore +1 more sourceModern Management of Asymptomatic Carotid Stenosis: A Meta‐Analysis of CREST‐2, SPACE‐2, and ECST‐2
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background
Recent randomized trials (CREST‐2, SPACE‐2, and ECST‐2) have compared carotid revascularization (carotid endarterectomy [CEA] or carotid artery stenting [CAS]) plus contemporary medical therapy (CMT) versus CMT alone in asymptomatic carotid stenosis.Aasim Ali, Waqar Ahmed Cheema, Fiza Nisar, Muhammad Shamoon, Sameen Sarfaraz, Ahmad Butt, Muhammad Abdullah Ali, Armaghana Abdullah, Muhammad Asad Shabbir, Muhammad Talha, Hammad Azam, Aimen Anwaar Pannun, Usama Saleem, Anousha Tanveer, Mukesh Sharma +14 morewiley +1 more sourceRe‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT
Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil +9 morewiley +1 more sourceMeasuring surgical safety during minimally invasive surgical procedures: A validation study [PDF]
, 2018 Background: During the implementation of new interventions (i.e., surgical devices and technologies) in the operating room, surgical safety might be compromised.Blikkendaal, Mathijs D. (author), Rodrigues, Sharon P. (author), Smeets, M.J.G.H., Frank Willem Jansen, Smeets, M.J.G.H. (author), Dobbelsteen, J.J. van den, Jenny Dankelman, Dankelman, J., Jansen, F.W., Sharon P. Rodrigues, Rodrigues, S.P., Jansen, F.W. (author), Mathijs D. Blikkendaal, John J. van den Dobbelsteen, Sara R. C. Driessen, Johann P. T. Rhemrev, Rhemrev, J.P.T. (author), Rhemrev, J.P.T., Driessen, S.R.C., Driessen, Sara R C (author), van den Dobbelsteen, J.J. (author), Blikkendaal, M.D., Maddy J. G. H. Smeets, Dankelman, J. (author) +23 morecore +1 more sourceArterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background/Objective
Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...Mona Asghariahmadabad, Pouya Metanat, Michael Thomas, Luke W. Bonham, Tyson Lam, Mehmet Kurt, Hong Nguyen, Tara Ellingson, Mauro Zucchelli, Stefano Casagranda, Quin Lu, Andreas M. Rauschecker, Leo Sugrue, Luis E. Savastano, Christopher P. Hess, Kamalini Ranasinghe, S. Andrew Josephson, Bruce L. Miller, Jennifer S. Yokoyama, Gil D. Rabinovici, Peter A. Ljubenkov, Lawren VandeVrede, Kambiz Nael +22 morewiley +1 more sourceChallenges in evaluating surgical innovation [PDF]
, 2009 Research on surgical interventions is associated with several methodological and practical challenges of which few, if any, apply only to surgery. However, surgical evaluation is especially demanding because many of these challenges coincide.Ergina, Patrick L, Seiler, Christoph M, Boutron, Isabelle, Blazeby, Jane M, Cook, Jonathan Alistair, Clavein, Pierre-Alain, Reeves, Barnaby C +6 morecore +2 more sourcesAlzheimer's Disease Biomarkers Measured by Capillary Blood Collection Versus Venous Plasma and Cerebrospinal Fluid
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
Blood biomarkers are increasingly critical for non‐invasive Alzheimer's Disease (AD) diagnostics and research but typically require on‐site processing. Remote point‐of‐care collection methods could enhance biomarker testing in clinical and research settings.Sara Ho, Ziling Shen, Alexandria Lewis, Megha Patel, Anny Zheng, Gianna Proscino, Thaovy Ho, Jiangxia Wang, Marilyn Albert, Abhay Moghekar +9 morewiley +1 more sourceCerebrospinal Fluid Over Plasma Links Analytes to Cognitive Decline in Older Adults at Risk for Alzheimer's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods
In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...Jagan A. Pillai, Audrey Zhu, Chunxuan Ma, Ming Wang, Yifan Yang, Lynn M. Bekris, Maria Khrestian, Frank P. DiFilippo, Mikhail Nasrallah, Aaron Burberry, James B. Leverenz, Yuan Hou, Feixiong Cheng, Stephen M. Rao +13 morewiley +1 more source