Results 241 to 250 of about 699,190 (350)

War, what is it good for? orthopedics the evolution of orthopedic surgery through armed conflict. [PDF]

Bull Hosp Jt Dis (2013)
Duenes ML, Egol KA.
europepmc   +1 more source

Bench‐to‐Bedside Translation of Self‐Healing Colloidal Hydrogels as Next Generation Design of Flowable Hemostatic Matrix: From Preclinical Evaluation to Human Clinical Trials

Advanced Science, EarlyView.
ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng, Kaiwen Chen, Qiwei Ying, Shuya Wang, Xin Li, Guanlin Li, Yantao Zhao, Binghua Ma, Huanan Wang, Dawei Li, Lijun Zhang, Jian Zhang, Yu Zhao, Changle Ren, Baodong Chen, Yueming Song   +15 more
wiley   +1 more source

Use of cover stent as treatment of iatrogenic iliac vein injury: Case series and review of the literature. [PDF]

J Vasc Surg Venous Lymphat Disord
Liu F, Chen F, Luo H, Qi X, Sun J, Chen Y.   +5 more
europepmc   +1 more source

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

Advanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi, Andrew E. Miller, Li Diao, Xinying Guo, Natalie Andonian, Elham Karimizadeh, Thomas H. Barker, Boris Hinz   +7 more
wiley   +1 more source

Acute Traumatic Aortic Injury: What the Radiologist Needs to Know. [PDF]

Tomography
Ramirez-Garcia K, Jaramillo C, Ferguson E, Au J, Odisio E, Oderich GS, Ocazionez D, Duran C, Macedo T.   +8 more
europepmc   +1 more source

Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy

Advanced Science, EarlyView.
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee, Chul‐Gyun Lim, Pothiappan Vairaprakash, Jong‐Min Kim, Jiyoon Kim, Ji‐Young Park, Klaus M. Hahn, Hyunbo Shim, Hae Woong Choi, Tobias S. Ulmer, Soon Jun Hong, Chungho Kim   +11 more
wiley   +1 more source

American Association for the Surgery of Trauma-World Society of Emergency Surgery Guidelines on the diagnosis and management of cervical vascular injuries. [PDF]

J Trauma Acute Care Surg
Kobayashi L, Perkins L, Johnston W, Kurth L, Black K, Abu-Zidan F, Augustin G, Balogh ZJ, Biffl WL, Britt LD, Catena F, Civil I, Coccolini F, Damaskos D, De'Angelis N, De Simone B, Galante JM, Góes AMO, Parreira JG, Hardcastle T, Inaba K, Kirkpatrick A, Kluger Y, Leppäniemi A, Maier R, Moore EE, Peitzman AB, Podda M, Sartelli M, Scalea TM, Stahel P, Tan E, Tolonen M, Weber D, Coimbra R.   +34 more
europepmc   +1 more source

Epithelial TRIM27 Inhibits Intestinal Inflammation in Ulcerative Colitis by the USP7/TRIM27‐IKK Double Negative‐Feedback

Advanced Science, EarlyView.
ABSTRACT The E3 ubiquitin ligase tripartite motif 27 (TRIM27) is a negative regulator of NF‐κB activation and the innate immune response, and TRIM27 deficiency significantly impairs dextran sulfate sodium (DSS)‐induced colitis. The function of TRIM27 in intestinal epithelial cells (IECs), the mechanism by which TRIM27 inhibits the NF‐κB pathway and its
Weimin Xu, Zhebin Hua, Zhujiang Dai, Shasha Zhang, Yihan Jiang, Wensong Ge, YingWei Chen, Zhongchuan Wang, Bing Zhang, Chen‐Ying Liu, Peng Du   +10 more
wiley   +1 more source

Patterns and outcomes of abdominal wound injuries in Sudanese armed conflict survivors: a retrospective cohort study. [PDF]

Trauma Surg Acute Care Open
Rafei A, Elsharif SA, Abdelraheem EM, Elamin MAA, Osman A, Salman M, Elbashier M, Ganim M, Rafei R, Alhajbakeet G, Abaker A, Mamoun M, Hussein A, Khalifa H.   +13 more
europepmc   +1 more source

Ultrasound‐Activated Bifunctional Piezoelectric Hydrogel Dressings Promote Infected Wound Healing via Regulating Angiogenesis and Lymphangiogenesis

Advanced Science, EarlyView.
This study developed a double‐network hydrogel with piezoelectric properties, exhibiting excellent antibacterial activity and promoting fibroblast migration, angiogenesis, and lymphangiogenesis through piezoelectric stimulation, thereby accelerating the healing of infected chronic wounds.
Xiang Li, Zhen Ding, Zhihua Liu, Hao Chen, Jianyang Shan, Yanxuan Shao, Yaling Yu, Gen Wen   +7 more
wiley   +1 more source