Results 111 to 120 of about 7,952,783 (243)

Anticancer drug delivery with transferrin targeted polymeric chitosan vesicles [PDF]

open access: yes, 2004
The study reports the initial biological evaluation of targeted polymeric glycol chitosan vesicles as carrier systems for doxorubicin (Dox). Transferrin (Tf) was covalently bound to the Dox-loaded palmitoylated glycol chitosan (GCP) vesicles using ...
Couet, William   +5 more
core   +1 more source

Dll4-notch signalling blockade synergizes combined ultrasound-stimulated microbubble and radiation therapy in human colon cancer xenografts.

open access: yesPLoS ONE, 2014
Tumour vasculature acts as an essential lifeline for tumour progression and facilitates metastatic spread. Novel vascular targeting strategies aiming to sustain vascular shutdown could potentially induce substantial damage, resulting in a significant ...
Ahmed El Kaffas   +5 more
doaj   +1 more source

Hypoxia-inducible factor 1 alpha is required for the tumourigenic and aggressive phenotype associated with Rab25 expression in ovarian cancer [PDF]

open access: yes, 2016
The small GTPase Rab25 has been functionally linked to tumour progression and aggressiveness in ovarian cancer and promotes invasion in three-dimensional environments.
Chalmers, Anthony J.   +3 more
core   +1 more source

CAR T cells as micropharmacies against solid cancers: Combining effector T-cell mediated cell death with vascular targeting in a one-step engineering process. [PDF]

open access: yesCancer Gene Ther, 2023
Altvater B   +18 more
europepmc   +1 more source

Tumor Vessel Development and Expansion in Ewing's Sarcoma: A Review of the Vasculogenesis Process and Clinical Trials with Vascular-Targeting Agents

open access: yesSarcoma, 2011
Ewing's sarcoma accounts for a disproportionately high portion of the overall pediatric mortality rate compared to its rare incidence in the pediatric population.
K. Stewart, E. Kleinerman
semanticscholar   +1 more source

Nanomedicine Faces Barriers

open access: yesPharmaceuticals, 2010
Targeted nanoparticles have the potential to improve drug delivery efficiencies by more than two orders of magnitude, from the ~ 0.1% which is common today.
Paul Debbage, Gudrun C. Thurner
doaj   +1 more source

Glycosylation-Engineered Platelet Membrane-Coated Interleukin 10 Nanoparticles for Targeted Inhibition of Vascular Restenosis

open access: yesInternational Journal of Nanomedicine, 2023
Fengshi Li,1,* Zhihua Rong,1,* Tianqi Chen,2 Peng Wang,1 Xiao Di,1 Leng Ni,1 Changwei Liu1 1Department of Vascular Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing ...
Li F   +6 more
doaj  

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