Results 121 to 130 of about 7,952,783 (243)

Subsequent Ultrasound Vascular Targeting Therapy of Hepatocellular Carcinoma Improves the Treatment Efficacy. [PDF]

Biology (Basel), 2021
Sultan LR, Karmacharya MB, Hunt SJ, Wood AKW, Sehgal CM.   +4 more
europepmc   +1 more source

Nanocarriers for targeted drug delivery in the vascular system: focus on endothelium

Journal of Nanobiotechnology
Endothelial cells (ECs) are pivotal in maintaining vascular health, regulating hemodynamics, and modulating inflammatory responses. Nanocarriers hold transformative potential for precise drug delivery within the vascular system, particularly targeting ...
Xiuxiu Cong, Zebin Zhang, He Li, Yong-Guang Yang, Yuning Zhang, Tianmeng Sun   +5 more
doaj   +1 more source

Cardiovascular ephrinB2 function is essential for embryonic angiogenesis [PDF]

, 2002
EphrinB2, a transmembrane ligand of EphB receptor tyrosine kinases, is specifically expressed in arteries. In ephrinB2 mutant embryos, there is a complete arrest of angiogenesis.
Anderson, David J., Gerety, Sebastian S.
core  

Targeting Reactive Astrocytes in Vascular Dementia: Investigation of Neuronal-Astrocyte-Vascular Interactions

Neuroscience Insights
Historically known as neuronal support cells, astrocytes are now widely studied for their close structural and functional interactions with multiple neural cell types and cerebral vessels where they maintain an ideal environment for optimized brain ...
Pradoldej Sompol
doaj   +1 more source

Perivascular adipose tissue: a central player in the triad of diabetes, obesity, and cardiovascular health

Cardiovascular Diabetology
Perivascular adipose tissue (PVAT) is a dynamic tissue that affects vascular function and cardiovascular health. The connection between PVAT, the immune system, obesity, and vascular disease is complex and plays a pivotal role in the pathogenesis of ...
Marcelo Queiroz, Cristina M. Sena
doaj   +1 more source

Bitter taste receptors in the gut-vascular axis: a novel target for immune and metabolic regulation of hypertension

Frontiers in Immunology
Hypertension affects approximately 1.3 billion adults worldwide, yet the control rate remains below 20%, highlighting the limitation of current therapies that primarily lower blood pressure without targeting the underlying pathophysiological mechanisms ...
Xiaoyu Wei, Feifei Lyu, Fuyun Jia, Lihong Zhang, Min Zhang, Qiang Xu, Shengyu Hua   +6 more
doaj   +1 more source

IMPROVING DRUG UPTAKE AND PENETRATION INTO TUMORS: CURRENT AND FORTHCOMING OPPORTUNITIES.

Frontiers in Oncology, 2013
Fabrizio eMarcucci, Fabrizio eMarcucci, Ronald eBerenson, Angelo eCorti   +3 more
doaj   +1 more source

Advances in intrahepatic and extrahepatic vascular dysregulations in cirrhotic portal hypertension

Frontiers in Medicine
Cirrhotic portal hypertension, the most prevalent and clinically significant complication of liver cirrhosis, manifests as elevated portal venous pressure and is associated with severe complications.
Yanqiu Li, Bingbing Zhu, Ke Shi, Yu Lu, Xuanwei Zeng, Yongqi Li, Qun Zhang, Ying Feng, Xianbo Wang   +8 more
doaj   +1 more source

Targeting PAK4 to reprogram the vascular microenvironment and improve CAR-T immunotherapy for glioblastoma

Nature Cancer, 2020
Wen-juan Ma, Yanling Wang, Rong-xin Zhang, Fan Yang, Duo Zhang, Menggui Huang, Lin Zhang, J. Dorsey, Zev A. Binder, D. O’Rourke, J. Fraietta, Y. Gong, Yi Fan   +12 more
semanticscholar   +1 more source

PAR1 Agonists Stimulate APC-Like Endothelial Cytoprotection and Confer Resistance to Thromboinflammatory Injury [PDF]

, 2018
Stimulation of protease-activated receptor 1 (PAR1) on endothelium by activated protein C (APC) is protective in several animal models of disease, and APC has been used clinically in severe sepsis and wound healing.
Aisiku, Omozuanvbo, Ceunynck, Karen De, Chaudhry, Sharjeel A., Dockendorff, Chris, Fitch-Tewfik, Jennifer L., Flaumenhaft, Robert, Higgins, Sarah J., Ingber, Donald E., Jain, Abhishek, Parikh, Samir M., Peters, Christian G.   +10 more
core   +1 more source