Results 41 to 50 of about 1,184,643 (261)

The Role of Chemotherapy in Pediatric Myoepithelial Carcinoma: A Systematic Review of the Literature

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Myoepithelial carcinoma (MEC) in pediatric patients is a rare and aggressive malignancy characterized by heterogeneous morphology and variable molecular features. The optimal role of chemotherapy remains unclear. We conducted a systematic review according to PRISMA 2020 guidelines to evaluate chemotherapy in pediatric and young‐adult patients ...
Marco Salvi, Maria Carmen Affinita, Giulia Fichera, Luisa Santoro, Angela Scagnellato, Calogero Virgone, Elena Poli, Gianni Bisogno   +7 more
wiley   +1 more source

Historical and contemporary management of infantile hemangiomas: a single-center experience

Frontiers in Pharmacology
Objective: This study explores the 22-year evolution of Infantile Hemangiomas (IHs) treatment strategies at a single-center hospital, aiming to establish an individualized IHs management protocol.Methods: Retrospective review of IHs infants 2000–2022 at ...
Yun Zou, Zhiping Wu, Pingliang Jin, Ronghua Fu, Jun Cheng, Hanxiang Bai, Mengyu Huang, Xiangqun Huang, Hua Yuan   +8 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Flow Dynamics and HSPC Homing in Bone Marrow Microvessels

Cell Reports, 2017
Measurements of flow velocities at the level of individual arterial vessels and sinusoidal capillaries are crucial for understanding the dynamics of hematopoietic stem and progenitor cell homing in the bone marrow vasculature.
M. Gabriele Bixel, Anjali P. Kusumbe, Saravana K. Ramasamy, Kishor K. Sivaraj, Stefan Butz, Dietmar Vestweber, Ralf. H. Adams   +6 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Superficial Femoral Artery Spontaneous Pseudoaneurysm Revealing Pleomorphic Vascular Wall Sarcoma

Clinical Case Reports
Vascular malignancy may rarely present as soft tissue swelling related to a spontaneous pseudoaneurysm. Our case report highlights the importance of prompt clinical examination, imaging, and surgical exploration for diagnosing vascular sarcoma presenting
Kamal Majed, Kaleem Mohammad Basharat, Hajar M. Anas Nassani, Suha Turkmen   +3 more
doaj   +1 more source

Machine learning to predict overall short-term mortality in cutaneous melanoma

Discover Oncology, 2023
Background Cutaneous malignant melanoma (CMM) ranks among the ten most frequent malignancies, clinicopathological staging being of key importance to predict prognosis.
C. Cozzolino, A. Buja, M. Rugge, A. Miatton, M. Zorzi, A. Vecchiato, P. Del Fiore, S. Tropea, A. Brazzale, G. Damiani, L. dall’Olmo, C. R. Rossi, S. Mocellin   +12 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Improved Biomass Production and Secondary Metabolism: A Critical Review of Grafting in Cannabis sativa

Plants
Cannabis sativa L. is a versatile plant with applications in various sectors such as agriculture, medicine, food, and cosmetics. The therapeutic properties of cannabis are often linked to its secondary compounds.
S. M. Ahsan, Md. Injamum-Ul-Hoque, Md. Mezanur Rahman, Sang-Mo Kang, In-Jung Lee, Hyong Woo Choi   +5 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source