Results 61 to 70 of about 75,847 (305)

Use of Intralesional and Perilesional Human Recombinant Epidermal Growth Factor (hrEGF) in the Local Treatment of Venous Ulcer – Review Article – Expert Recommendation

Vascular Health and Risk Management, 2023
Maria Teresa Cacua Sanchez,1 Lina M Vargas Abello,2 Álvaro Orrego,3 Paola Ortiz,4 Héctor Segura,5 Jhon Jairo Berrio Caicedo,6 Luz Marina Zuluaga,7 José Ordoñez,8 José Ignacio Fernández Montequin,9 Jorge Ulloa10 1Ambulatory Surgery Center, Kennedy ...
Cacua Sanchez MT, Vargas Abello LM, Orrego Á, Ortiz P, Segura H, Berrio Caicedo JJ, Zuluaga LM, Ordoñez J, Fernández Montequin JI, Ulloa J   +9 more
doaj  

MG53 Coordinates Macrophage Polarization and Neuroimmune Coupling to Promote Corneal Nerve Regeneration via the MPEG1–MVP–STAT6 Axis

Advanced Science, EarlyView.
Corneal nerve regeneration is critical to corneal wound healing processes. The current study reveals a novel role of MG53 in promoting corneal nerve regeneration after alkali induced injury. Mechanistically, MG53 enters macrophages via its receptor, MPEG1, promotes MVP K63 ubiquitination, and triggers STAT6 induced repair‐related genes expression ...
Peng Chen, Zhentao Zhang, Lilian Sakai, Yanping Xu, Luxi Zhang, Han Ye, William Sollenberger, Takahide Ikeda, Zhiyu Yan, Keerthika Sathish, Usman Alizai, Haitao Wen, Timothy M. Pawlik, Heather L. Chandler, Hua Zhu   +14 more
wiley   +1 more source

Treatment of Chronic Diabetic Foot Ulcers with Adipose-Derived Stromal Vascular Fraction Cell Injections: Safety and Evidence of Efficacy at 1 Year [PDF]

, 2021
Michael H. Carstens, Francisco J. Quintana, Santos T. Calderwood, Juan P. Sevilla, Arlen B. Ríos, Carlos Martínez‐Rivera, Dorian W. Calero, María L. Zelaya, Nelson García, Kenneth A. Bertram, Joseph Rigdon, Severiano Dos-Anjos, Diego Correa   +12 more
openalex   +1 more source

Multi‐Omics Profiling Reveals Immunomodulatory and Pro‐Regenerative Effects of a Graphene Oxide–Collagen Scaffold in Massive Rotator Cuff Tears

Advanced Science, EarlyView.
A graphene oxide/collagen scaffold is developed for chronic massive rotator cuff tear repair. The scaffold improves compressive stability, supports reparative mesenchymal differentiation, and modulates the immune microenvironment. In chronic MRCT models, it reduces muscle degeneration, enhances tendon–bone regeneration, and improves functional recovery,
Renwen Wan, Yechuan Deng, Zixin Hu, Yanwei He, Xinting Feng, Jun Ma, Yisheng Chen, Zhijie Zhao, Jie Mei, Zhiheng Lin, Wei Luo, Zhengyuan Fang, Zhufeng Hu, Kunlun Feng, Xinrong Li, Dan Wu, Bowen Han, James Hoi po Hui, Xuanyong Liu, Chen Chen, Gang Chen, Shiyi Chen, Nirong Bao, Jiajun Qiu, Zhiwen Luo   +24 more
wiley   +1 more source

Comparative Study Between Surgical Offloading and Mechanical Offloading in the Treatment of Chronic Plantar Foot Ulcers in Diabetic Patients [PDF]

Al-Azhar International Medical Journal
Background: One of the leading causes of mortality, diabetes mellitus (DM) impacts every part of the body. Both individuals and society bear the brunt of the pain and expense associated with foot disorders.
Mohamed Abd El-Rahman, Mohamed Zakaria, Abd El-Rahman Abdo   +2 more
doaj   +1 more source

Nanozymes for Advanced Hemoglobin‐Based Oxygen Carriers: Applications in Blood Substitution, Wound Healing, Antitumor Therapy, and Beyond

Advanced Science, EarlyView.
This review explores how hemoglobin‐based oxygen carriers (HBOCs) combined with nanozymes create multifunctional materials that deliver oxygen while maintaining redox homeostasis. Beyond artificial blood substitutes, these constructs enable wound healing with light‐triggered oxygen release, cancer therapy through enhanced oxygenation and reactive ...
Despoina Douka, Ana María Pablo‐Sainz‐Ezquerra, Eva Jakljevič, Niki Ktena, Leticia Hosta‐Rigau   +4 more
wiley   +1 more source

Light‐Switched Mesenchymal Stem Cells for In Situ Exosome Amplification in Craniofacial Bone Defect Reconstruction

Advanced Science, EarlyView.
Light‐switchable MSCs (MSC‐UCNPs) were constructed by intracellular incorporation of UCNPs. Upon 980 nm irradiation, UCNPs emitted localized ultraviolet light (365 nm), activating the ROS/HEXB/LAMP1 signaling pathway to suppress lysosome–multivesicular body fusion and thereby enhance exosome biogenesis. Embedded within an injectable hydrogel, MSC‐UCNPs
Tingting Wu, Yajing Liu, Shuman Wang, Xiaoming Bai, Luyun Zhang, Yuwei Liu, Zhiwen Fu, Chen Shi   +7 more
wiley   +1 more source

Effect of betablockers on the course of Martorell hypertensive ulcers: a retrospective study

Acta Dermato-Venereologica
Martorell hypertensive ulcer (MHU) represents a painful, difficult-to-handle condition associated with peri-pheral, subcutaneous arteriolosclerosis caused by chronic hypertensive disease.
Lucy Cleusix, Olesya Pavlova, Emmanuella Guenova, François Kuonen   +3 more
doaj   +1 more source

A Sprayable Nanoplatform Breaks the Vicious Cycle of Diabetic Wounds via Photoactivated Antioxidant and Drug Delivery

Advanced Science, EarlyView.
A sprayable near‐infrared‐activated nanoplatform incorporating MXene, ZnHCF nanozyme, and deferoxamine efficiently breaks the vicious cycle of diabetic wounds. Upon irradiation, interfacial electron transfer and photothermal effects enhance multi‐enzyme activity, enabling explosive ROS elimination, alleviation of hypoxia, and controlled DFO release ...
Jiahao Guo, Yuanyuan Meng, Qixiang Gui, Xi‐Tao Yang, Yong Fan, Xiaodong Zhu   +5 more
wiley   +1 more source

EVALUATION OF THE DIABETIC FOOT

Eurasian Journal of Medicine, 2019
Foot ulcers are a major cause of diability, morbidity and mortality in people with diabetes. The three major etiological factors for diabetik foot ulcers are peripheral neuropathy, peripheral vascular disease and infection. Tight control of blood glucose
İlyas Çapoğlu, Mehmet Oğuz Yenidünya, Necdet Ünüvar   +2 more
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