This review examines the potential of in vivo direct reprogramming in regenerative medicine for functional tissue restoration, highlighting the role of tissue‐resident cues in generating functionally mature reprogrammed cells from lineage‐related cells. It contains a discussion on mechanisms, reprogramming factors, delivery approaches, and applications
Rishabh Deo Singh +2 more
wiley +1 more source
Modification of free vascularized fibular graft and its use in upper limb injuries
The restoration with conventional osteogenic contributions is unpredictable with regard to major defects because it integrates as it consolidates their ends as a fracture. In this work, innovations in free vascularized fibular graft were made, one of the
José Ramón Lara Espinosa +1 more
doaj
Comparison of the functional and radiological outcomes of vascularized and non-vascularized bone graft options in the treatment of scaphoid nonunion. [PDF]
Maraşlı MK, Kibar B, Cavit A.
europepmc +1 more source
INTRODUCTION: Reconstruction of skeletal bone defects following trauma, tumour resection and infective resorption are always challenging for orthopaedic surgeons.
Kumaresan, N
core
Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert +8 more
wiley +1 more source
Possibilities and results of (free) vascularized bone graft of the hand and wrist
The vascularized bone transplantation or graft is a modern and successful treatment concept in segmental bone loss. Faster healing and higher union rates were shown in several studies. Using vascularized bone grafts, the adaption in mechanical conditions
Sauerbier M. +2 more
core +1 more source
Mesenchymal Stromal Cell‐Based Cell–Drug Conjugates for the Treatment of Acute Liver Failure
Mesenchymal stromal cell (MSC)‐based cell‐drug conjugates are constructed by anchoring rosiglitazone‐loaded nanoparticles onto the MSC surface. Sustained rosiglitazone release enhances MSC proliferation and paracrine activity while promoting anti‐inflammatory macrophage polarization.
Tenghui Ye +6 more
wiley +1 more source
Use of non-vascularized autologous fibula strut graft in the treatment of segmental bone loss [PDF]
Background : Fractures resulting in segmental bone loss challenge the orthopedic surgeon. Orthopedic surgeons in developed countries have the option of choosing vascularized bone transfers, bone transport, allogenic bone grafts, bone graft substitutes ...
Garba, ES +14 more
core +1 more source
Comparison of Kirschner Wire Versus Screw Fixation in 1,2 Inter-Compartment Supra Retinaculum Artery Pedicle-Vascularized Bone Graft for Scaphoid Fractures. [PDF]
Muhammad Ali A +3 more
europepmc +1 more source
Atlantoaxial pseudoarthrosis is a challenging postoperative complication. The use of a local, vascularized bone graft, without free tissue transfer, to support a revision atlantoaxial fusion has not been previously described. We report the first surgical
Chang, Steve W. +16 more
core +1 more source

