Results 91 to 100 of about 298,746 (351)
A case of abdominal sarcoidosis in a patient with acute myeloid leukemia. [PDF]
, 2013 The allogeneic bone marrow transplantation usually preceded by induction chemotherapy, in fit patients, represents the gold standard in the acute myeloid leukaemia.Addeo, Alfredo, Athithan, Lavanya, Baskaran, Vadsala, Goodwin, Amanda, Rinaldi, Ciro +4 morecore +2 more sourcesAdjunctive Treatment With Avacopan, an Oral C5a Receptor Inhibitor, in Patients With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis
ACR Open Rheumatology, 2020 This study aimed to evaluate the safety of avacopan, an orally administered C5a receptor inhibitor, for the treatment of antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis in addition to standard‐of‐care (SOC) treatment with glucocorticoids P. Merkel, J. Niles, R. Jiménez, R. Spiera, B. Rovin, A. Bomback, C. Pagnoux, A. Potarca, T. Schall, P. Bekker +9 moresemanticscholar +1 more sourceAuthor Correction: BAFF, APRIL and BAFFR on the pathogenesis of Immunoglobulin-A vasculitis [PDF]
, 2021 Diana Prieto-Peña, Fernanda Genre, Sara Remuzgo‐Martínez, Verónica Pulito‐Cueto, Belén Atienza‐Mateo, Javier Llorca, Belén Sevilla‐Perez, Norberto Ortego‐Centeno, Leticia Lera‐Gómez, María Teresa Leonardo, Ana Peñalba, Javier Narváez, Luis Martín‐Penagos, Emilio Rodrigo, José A. Miranda‐Filloy, Luis Caminal‐Montero, Paz Collado, Javier Sánchez Pérez, D. de Argila, Estéban Rubio, Manuel León Luque, Juan María Blanco-Madrigal, E. Galíndez-Agirregoikoa, Oreste Gualillo, Javier Martı́n, Santos Castañeda, Ricardo Blanco, Miguel Á. González‐Gay, Raquel López‐Mejías +28 moreopenalex +1 more sourceExpert Perspective: Diagnosis and Treatment of Castleman Disease
Arthritis &Rheumatology, EarlyView.Castleman disease (CD) is a major diagnostic challenge for rheumatologists. Unicentric CD (UCD) involves one enlarged lymph node region, whereas multicentric CD (MCD) involves multiple enlarged lymph node regions. Both UCD and MCD may exhibit a wide range of symptoms that overlap with other immune‐mediated conditions.Luke Y. C. Chen, Lu Zhang, David C. Fajgenbaum +2 morewiley +1 more sourceImmPort, toward repurposing of open access immunological assay data for translational and clinical research [PDF]
, 2018 Immunology researchers are beginning to explore the possibilities of reproducibility, reuse and secondary analyses of immunology data. Open-access datasets are being applied in the validation of the methods used in the original studies, leveraging ...Bhattacharya, Sanchita, Butte, Atul, Chen, Jieming, Dunn, Patrick, Hu, Zicheng, Schaefer, Henry, Shankar, Ravi, Shen-Orr, Shai, Smith, Barry, Thomas, Cristel, Thomson, Elizabeth, Wiser, Jeffrey, Zalocusky, Kelly +12 morecore +2 more sourcesImmunopathogenesis of ANCA-Associated Vasculitis
International Journal of Molecular Sciences, 2020 Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis is an autoimmune disorder which affects small- and, to a lesser degree, medium-sized vessels.A. Kronbichler, Keumwha Lee, Sara Denicolò, D. Choi, H. Lee, D. Ahn, Kang Hyun Kim, Ji Han Lee, Hyungtae Kim, Min-Seung Hwang, S. Jung, Changjun Lee, Hojune Lee, H. Sung, Dongkyu Lee, Jae-Kyung Hwang, So-Hun Kim, I. Hwang, D. Y. Kim, Hyung Jun Kim, Geonjae Cho, Yunryoung Cho, Dong-Il Kim, Minje Choi, Junhyeong Park, Junseong Park, K. Tizaoui, Han Li, Lee Smith, A. Koyanagi, L. Jacob, P. Gauckler, J. Shin +32 moresemanticscholar +1 more sourceAmerican College of Rheumatology Guidance Statement for Diagnosis and Management of VEXAS Developed by the International VEXAS Working Group Expert Panel
Arthritis &Rheumatology, EarlyView.Objective
Vacuoles E1 enzyme X‐linked autoinflammatory somatic syndrome (VEXAS) is a recently identified rare genetic disorder associated with somatic mutations in the UBA1 gene. VEXAS presents with a combination of inflammatory and hematologic manifestations, leading to increased morbidity and mortality.Arsene Mekinian, Sophie Georgin‐Lavialle, Marcela A. Ferrada, Sinisa Savic, Matthew J. Koster, Olivier Kosmider, Thibault Comont, Mael Heilblig, Juan I. Arostegui, Annmarie Bosco, Rim Bourguiba, Katherine R. Calvo, Catherine Cargo, Chiara Cattaneo, François Chasset, Henrique Coelho, Corrado Campochiaro, Francesca Crisafulli, Stephanie Ducharme‐Benard, Raquel Faria, Franco Franceschini, Micol Frassi, Emma M. Groarke, Carmelo Gurnari, Yervand Hakobyan, Yvan Jamilloux, Ciprian Jurcut, Yohei Kirino, Austin Kulasekararaj, Hiroyoshi Kunimoto, Lauren M. Madigan, Heřman F. Mann, Chiara Marvisi, Marcin Milchert, Sara Morais, Katja Sockel, Francesco Muratore, Hideaki Nakajima, Mrinal M. Patnaik, Luísa Regadas, Marie Robin, Abraham Rutgers, Carlo Salvarani, Anthony M. Sammel, Joerg Seebach, Pierre Sujobert, Alessandro Tomelleri, Geoffrey Urbanski, Frédéric Vandergheynst, Romana Vieira, David S. Viswanatha, Ewa Więsik‐Szewczyk, Elisa Diral, Benjamin Terrier, Bhavisha A. Patel, Pierre Fenaux, Peter C. Grayson, David B. Beck, on behalf of the International VEXAS working group, and with endorsement of EuroBloodNet, the European Reference Network in Rare Hematological Diseases, Heřman Mann, Benjamin Terrier, François Chasset, Sophie Georgin Lavialle, Alessandro Tomelleri, Campochiaro Corrado, Carlo Salvarani, Francesca Crisafulli, Franco Franceschini, Micol Frassi, Yohei Kirino, Ewa Więsik‐Szewczyk, Marcin Milchert, Raquel Faria, Ciprian Jurcut, Joerg Seebach, Sinisa Savic, David Beck, Lauren Madigan, Matthew Koster, Patnaik Mrinal, Olivier Kosmider, Pierre Sujobert, Juan I. Arostegui, Catherine Cargo, David Viswanatha, Yervand Hagopian, Mael Heilblig, Pierre Fenaux, Thibault Comont, Bruno Alessandro, Chiara Cattaneo, Elisa Diral, Sara Morais, Austin Kulasekarara, Emma Groarke, Katherine Calvo, Patel Bhavisha, Anthony Sammel, Arsene Mekinian, Benjamin Terrier, Marie Robin, Sophie Georgin Lavialle, Katja Sockel, Yvan Jamilloux, Carmelo Gurnari, Henrique Coelho, Romana Vieira, Rim Bourguiba, Marcela Ferrada, Peter Grayson +111 morewiley +1 more sourceLate‐Onset Spondyloarthritis Presenting as Glucocorticoid‐Resistant Polymyalgia Rheumatica: A Hitherto Underappreciated Entity in Which Tumor Necrosis Factor or Interleukin ‐17 Blockade May Have a Therapeutic Role
Arthritis &Rheumatology, EarlyView.Objective
Polymyalgia rheumatica (PMR) is an age‐related inflammatory disease with shoulder/hip girdle involvement. Magnetic resonance imaging (MRI) reveals extracapsular/entheseal soft tissue involvement in both PMR and spondyloarthritis (SpA), with sacroiliac joint and perientheseal spinal bone marrow edema (BME) being characteristic of SpA ...Kerem Abacar, Gabriele De Marco, Jake Weddell, Katya Meridor, Tom Macleod, Andrew Scarsbrook, Kulveer Mankia, Edward Vital, Andrew Barr, Colin Pease, Helena Marzo‐Ortega, Sarah L. Mackie, Dennis McGonagle +12 morewiley +1 more sourceInterleukin-7 deficiency in rheumatoid arthritis: consequences for therapy-induced lymphopenia [PDF]
, 2004 We previously demonstrated prolonged, profound CD4+ T-lymphopenia in rheumatoid arthritis (RA) patients following lymphocyte-depleting therapy. Poor reconstitution could result either from reduced de novo T-cell production through the thymus or from poor Bingham, S.J., Brown, A.K., Buch, M., Douglas, S.H., Emery, P., Fearon, U., Field, S.L., Isaacs, J.D., Lawson, C.A., Ma, D., Maltby, S.L., Markham, A.F., Masurel, A., McGonagle, D., Moore, J., Morgan, A.W., Papadaki, H.A., Patel, P., Ponchel, F., Protheroe, A., Quinn, M., Short, K., Snowden, J., Straszynski, L., van Laar, J.M., Veale, D.J., Verburg, R.J. +26 morecore +2 more sources
