Results 151 to 160 of about 109,399 (240)

Increased p‐Tau181 Levels After Overnight Wakefulness Are Associated With Neuroticism in Young Women

open access: yesJournal of Sleep Research, EarlyView.
Overnight wakefulness, mimicking night shift conditions, impaired morning vigilance in healthy, reproductive‐aged women, regardless of estradiol or neuroticism. However, the overnight wakefulness‐related rise in the Alzheimer's disease blood biomarker p‐Tau181 was greater in women with higher neuroticism, suggesting that neurobiological vulnerability ...
Diana A. Nôga   +14 more
wiley   +1 more source

Comparative Pharmacokinetics of Intranasal or Intramuscular Atipamezole in Unsedated Dogs and Efficacy for Reversal of Xylazine Sedation

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The objectives of this study were to evaluate ATIP pharmacokinetics (PK) in healthy Beagle dogs after IM and IN dosing (Phase I), and to compare the rate of reversal of IM versus IN routes for xylazine (XYL) sedation (Phase II). This study was comprised of two sequential, randomized, crossover experiments. The initial PK study dosed ATIP by IN
Vanessa E. Cowan   +7 more
wiley   +1 more source

Exposure to Subcutaneously Administered Butorphanol in Horses Pre‐Treated With Detomidine or Detomidine‐Vatinoxan

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The aim of the study was to determine the exposure to subcutaneously administered butorphanol in horses pre‐treated with intravenous (IV) detomidine, with or without vatinoxan, a peripherally selective alpha2‐adrenoceptor antagonist. Five healthy, adult horses received three IV treatments 7 days apart, in a randomized, cross‐over design ...
Juhana M. Honkavaara   +5 more
wiley   +1 more source

Pharmacokinetics of Long‐Acting Ampicillin and Its Impact on the Gut Microbiome and Resistome in Rhesus Macaques (Macaca mulatta)

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Injectable antimicrobials with documented prolonged dosing intervals (> 48 h) for use in rhesus macaques are sparse. The objective of our study was to assess the pharmacokinetics, urine excretion, and effects on gut microbiome and resistome of intramuscular administered long‐acting formulation of ampicillin (Albipen LA) in macaques.
Annemiek Maaskant   +9 more
wiley   +1 more source

Non-invasive Coronary Functional Tests in Patients with Angina and Non-obstructive Coronary Artery Disease. [PDF]

open access: yesEur Cardiol
Cambise N   +14 more
europepmc   +1 more source

CEREBRAL VASOCONSTRICTION

open access: yesBritish Journal of Anaesthesia, 1965
openaire   +1 more source

An eye on long‐duration spaceflight: Controversies, countermeasures and challenges

open access: yesExperimental Physiology, EarlyView.
Abstract Space flight‐associated neuroocular syndrome (SANS) is a consequence of long‐duration space flight and is detected in two‐thirds of astronauts. In‐flight, this can cause a change in the refraction of the eyes, requiring graded hypermetropic ‘superfocus adjustable’ glasses, optic nerve head oedema and choroidal folds.
Vincent Wing Sum Ng   +1 more
wiley   +1 more source

Autonomic neurotransmission in cardiovascular regulation and pathophysiology. [PDF]

open access: yesFront Neurosci
Varzideh F   +4 more
europepmc   +1 more source

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