Results 151 to 160 of about 9,502 (211)

Senescent Endothelial Cells in Cerebral Microcirculation Are Key Drivers of Age‐Related Blood–Brain Barrier Disruption, Microvascular Rarefaction, and Neurovascular Coupling Impairment in Mice

Aging Cell, EarlyView.
Senolytic therapy restores neurovascular function, blood–brain barrier integrity, and cognitive performance in aged mice by targeting endothelial senescence. Findings highlight that brain microvascular endothelial cells are highly vulnerable to aging‐induced senescence, and early intervention in middle age may be the most effective strategy to prevent ...
Boglarka Csik, Ádám Nyúl‐Tóth, Rafal Gulej, Roland Patai, Tamas Kiss, Jordan Delfavero, Raghavendra Y. Nagaraja, Priya Balasubramanian, Santny Shanmugarama, Anna Ungvari, Siva Sai Chandragiri, Kiana Vali Kordestan, Mark Nagykaldi, Peter Mukli, Andriy Yabluchanskiy, Sharon Negri, Stefano Tarantini, Shannon Conley, Tae Gyu Oh, Zoltan Ungvari, Anna Csiszar   +20 more
wiley   +1 more source

Impaired acetylcholine-mediated vasodilation in patients with congestive heart failure. Role of endothelium-derived vasodilating and vasoconstricting factors. [PDF]

, 1993
Stuart D. Katz, Michael Schwarz, Jeannette Yuen, Thierry H. LeJemtel   +3 more
openalex   +1 more source

Dietary Restriction Mitigates Vascular Aging, Modulates the cGAS‐STING Pathway and Reverses Macrophage‐Like VSMC Phenotypes in Progeroid DNA‐Repair‐Deficient Ercc1Δ/− Mice

Aging Cell, EarlyView.
Dietary restriction mitigates vascular aging in DNA‐repair‐deficient Ercc1Δ/− mice by reducing extracellular matrix remodeling, inflammation, oxidative stress, and switching of vascular smooth muscle cells to a macrophage‐like phenotype. Our findings suggest that the cGAS‐STING pathway plays a key role in vascular aging and that the benefits of dietary
S. J. M. Stefens, J. van der Linden, J. M. Heredia‐Genestar, R. M. C. Brandt, S. Barnhoorn, I. Nieuwenhuizen‐Bakker, N. van Vliet, J. H. M. Odijk, Y. Ridwan, D. Stuijts, M. Batenburg, J. H. J. Hoeijmakers, R. Kanaar, J. Essers, I. van der Pluijm   +14 more
wiley   +1 more source

STUDY OF COLD-INDUCED VASODILATION DUE TO COLD EXPOSURE

, 1988
MASASHI SUGAHARA
openalex   +2 more sources

Suppression of insulin-induced sympathetic activation and vasodilation by dexamethasone in humans. [PDF]

, 1993
Urs Scherrer, Péter Vollenweider, D Randin, E Jéquier, Pascal Nicod, Luc Tappy   +5 more
openalex   +1 more source

Dual Inhibition of Mast Cells and Thymic Stromal Lymphopoietin Using a Novel Bispecific Antibody, CDX‐622

Allergy, EarlyView.
SCF and TSLP expression are known to drive unique immune responses leading to the onset of allergic and inflammatory diseases. Here, we describe the characterization of a novel bsAb, CDX‐622, that targets SCF and TSLP. CDX‐622 inhibits MC functions through SCF starvation and Type 2 inflammatory responses via TSLP inhibition.
Michael B. Murphy, Laura Vitale, Thomas O'Neill, Deena M. Maurer, Linda Malenchek, Andrea Crocker, Colleen Patterson, Laura Mills‐Chen, Virginia Saley, Nicole M. Antczak, James M. Boyer, Kelly M. McManus, Noe Rico Montanari, Russell A. Hammond, Joel Goldstein, Lawrence J. Thomas, Tibor Keler, Diego Alvarado   +17 more
wiley   +1 more source

Vasodilation produced by forskolin compared with the relaxation of adenosine in rabbit coronary artery

, 1985
Hiroshi Hisajima, Teruo Hama, Kazuyoshi Kurahashi, Motohatsu Fujiwara   +3 more
openalex   +1 more source

Elderberries as a potential supplement to improve vascular function in a SARS‐CoV‐2 environment

Journal of Food Biochemistry, Volume 46, Issue 11, November 2022., 2022
Elderberry extract (EE) can target both viral infection and vascular dysfunction which could be a useful strategy to reduce morbidity and mortality relating to COVID‐19. Literature looks promising and builds a suggestion for investigating EE against COVID‐19. However, further in vitro and in vivo research is required to fully evaluate elderberries as a
Joseph Festa, Harprit Singh, Aamir Hussain, Mariasole Da Boit   +3 more
wiley   +1 more source

The mode of vasodilation of atrial natriuretic factor (ANF) in rabbit and rat aorta

, 1985
Takashi Shinohara, Akiko Ishikawa, Jun Inui   +2 more
openalex   +1 more source

Bioactive food components and their inhibitory actions in multiple platelet pathways

Journal of Food Biochemistry, Volume 46, Issue 12, December 2022., 2022
A comprehensive overview of platelet multifunctional roles in CVD and other diseases and the effects of food components' modulatory effects are described. Abstract In addition to hemostasis and thrombosis, blood platelets are involved in various processes such as inflammation, infection, immunobiology, cancer metastasis, wound repair and angiogenesis ...
Diptimayee Das, Shubhamay Adhikary, Ranjit Kumar Das, Antara Banerjee, Arun Kumar Radhakrishnan, Sujay Paul, Surajit Pathak, Asim K. Duttaroy   +7 more
wiley   +1 more source