Results 181 to 190 of about 53,380 (285)

Patient‐Specific Haemodynamic Modeling to Estimate the Extent of Microvascular Disease and Response to Pulmonary Endarterectomy in Chronic Thromboembolic Pulmonary Hypertension

Pulmonary Circulation, Volume 15, Issue 4, October 2025.
ABSTRACT Chronic thromboembolic pulmonary hypertension (CTEPH) is a form of pulmonary hypertension that is caused by persistent obstruction of the pulmonary arteries by organized thrombi and associated microvascular disease. Pulmonary endarterectomy (PEA) is the gold standard treatment, but the extent of small vessel remodeling, which strongly ...
Behdad Shaarbaf Ebrahimi, Prashanna Khwaounjoo, Ho‐Fung Chan, Finbar Argus, Xiaohui Ma, Martyn P. Nash, Atsuo Doi, Misha Dagan, David M. Kaye, Timothy Joseph, David McGiffin, Merryn H. Tawhai   +11 more
wiley   +1 more source

Late Onset Pulmonary Arterial Hypertension Associated With Features of Pulmonary Veno‐Occlusive Disease and Rare Heterozygous Variants of KDR and EIF2AK4

Pulmonary Circulation, Volume 15, Issue 4, October 2025.
ABSTRACT The natural history of late‐onset pulmonary arterial hypertension (PAH) with features of venous/capillary involvement and the associations with rare variants in PAH genes are not well known. We report a case of a female patient who developed severe PAH at the age of 70.
Vasile Foris, Luka Brcic, Peter Dorfmüller, Christina A. Eichstaedt, Ekkehard Grünig, Philipp Douschan, Teresa John, Katarina Zeder, Michael Fuchsjäger, Nikolaus Kneidinger, Gabor Kovacs, Horst Olschewski   +11 more
wiley   +1 more source

Experimental Study of the Isolated Canine Kidney Perfusion with Special Reference to Effects of Various Vasodilator Agents

, 1970
CHEN TIE HWANG, EIAKI TSUTSUMI, Hiroshi Suzuki, Kazuhiko Takano, Naoya Matoba   +4 more
openalex   +2 more sources

Therapeutic Oligonucleotides for Neurodegenerative Diseases: Aptamer Strategies and Clay Nanoparticle‐Based Delivery

The Chemical Record, Volume 25, Issue 10, October 2025.
This review explores aptamers as therapeutic oligonucleotides targeting neurodegenerative diseases, including Alzheimer's, Parkinson's, and Huntington's, with a focus on G‐quadruplex‐forming sequences. It discusses chemical modifications that enhance aptamer stability and function, alongside the use of clay nanoparticles, such as halloysite nanotubes ...
Valentina Arciuolo, Federica D’Aria, Maria Rita Caruso, Martina Maria Calvino, Jussara Amato, Giuseppe Lazzara, Stefana Milioto, Concetta Giancola, Giuseppe Cavallaro, Bruno Pagano   +9 more
wiley   +1 more source

A case report of a multivessel coronary vasospasm that responded to IV diazepam. [PDF]

Medicine (Baltimore)
Abboud F, Zain M, Alsaadi A, Haneyah F, Jama A, Bayat G.   +5 more
europepmc   +1 more source

Influence of inhibitors of prostaglandin synthesis on renal vascular resistance and on renal vascular responses to vasopressor and vasodilator agents in the cat.

, 1977
B. M. Chapnick, P.W. Paustian, Larry P. Feigen, Paul D. Joiner, Albert L. Hyman, Philip J. Kadowitz   +5 more
openalex   +1 more source

Levosimendan, a New Inotropic and Vasodilator Agent [PDF]

, 2006
Wolfgang Toller, Christian Stranz, David C. Warltier   +2 more
openalex   +1 more source

Drug repurposing: isosorbide mononitrate enhances tumor accumulation to augment sonodynamic therapy for hepatocellular carcinoma. [PDF]

J Nanobiotechnology
Peng Y, Li Z, Zhou L, Jian Q, Yin B, Sun B, Song Y, Chen H, Tan X, Duan X, Liu S, Peng C, Song G.   +12 more
europepmc   +1 more source

Evaluation of Nitrosyl Ruthenium Complexes Entrapped in an Oil-In-Water Emulsion as Vasodilator Agents [PDF]

, 2008
Mario Marchesi, Wagner Luiz Heleno Marcus Bertolini, Simone Aparecida Cicillini, Daniella Bonaventura, Lusiane Maria Bendhack, Renata Fonseca Vianna Lopez, Roberto Santana da Silva   +6 more
openalex   +1 more source

Clinically relevant niclosamide concentrations modulate TMEM16A and CaV1.2 channels to control artery tone and capillary diameter

British Journal of Pharmacology, Volume 182, Issue 19, Page 4490-4515, October 2025.
Abstract Background and Purpose TMEM16A Ca2+‐gated Cl− channels mediate depolarisation of contractile vascular cells. The anthelmintic niclosamide was reported to modulate the TMEM16A channel, suggesting possible repurposing for vascular pharmacology. Here, we investigate the mechanism of TMEM16A modulation by niclosamide and explore its effect on the ...
Rachel Kaye, Claire Pearson, Tibyan Babiker, Emilio Agostinelli, Rumaitha Al‐Hosni, Paolo Tammaro   +5 more
wiley   +1 more source