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Pulmonary vasodilator use in very preterm infants in United States children's hospitals. [PDF]
Vega TF +8 more
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GSNO as a Modulator of Vascular Tone in Human Saphenous Veins: Potential Implications for Graft Spasm. [PDF]
Kaleli Durman D +5 more
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Alkaloids as Vasodilator Agents: A Review
Current Pharmaceutical Design, 2023Abstract: The pathophysiology of hypertension is often associated with endothelial dysfunction and the impairment of endothelium-dependent vasodilation mechanisms, as well as alterations in vascular smooth muscle (VSM) tone. Natural products, particularly alkaloids, have received increased attention in the search for new vasodilator agents.
Ayoub, Amssayef, Mohamed, Eddouks
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2015
This chapter discusses the salient features of arterial and venous dilating agents commonplace in the management of the post-cardiotomy surgical patient. A keen understanding of the underlying cellular mechanism, pharmacology, indication, safety profile, and controversies of clinical utility of vasodilating agents is imperative for routine use.
Shreyajit R. Kumar +2 more
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This chapter discusses the salient features of arterial and venous dilating agents commonplace in the management of the post-cardiotomy surgical patient. A keen understanding of the underlying cellular mechanism, pharmacology, indication, safety profile, and controversies of clinical utility of vasodilating agents is imperative for routine use.
Shreyajit R. Kumar +2 more
openaire +1 more source
Intratracheal administration of pulmonary vasodilator agents
Pediatric Pulmonology, 1992AbstractWe compared intravenous and intratracheal administration of histamine (0.4 and 1.6 kg/kg, respectively) and nitroglycerin (5.0 and 20.0 μg/kg, respectively) in seven hypoxemic 2 week old lambs, during right lung only perfusion, to see if intratracheal administration could limit their vasodilator action to the pulmonary vessels.
M A, D'Angeli, B W, Goetzman
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Positive Inotropic/Vasodilator Agents
Cardiology Clinics, 1989Beta-adrenergic sympathomimetic agents such as dobutamine and dopamine, and phosphodiesterase inhibitors such as amrinone, milrinone, and enoxamone, exert a direct positive inotropic effect upon the myocardium by causing an increase in cyclic AMP levels. The phosphodiesterase inhibitors also exert a substantial direct vasodilator effect.
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Vasodilators as Antihypertensive Agents
1982In this chapter, we will analyse the mode of action and therapeutic use of the ‘direct-acting smooth muscle relaxant antihypertensor drugs’. We will include in this class of drugs those antihypertensive compounds which are supposed to relax vascular smooth muscle without interfering with identified cell receptors (adrenergic, dopaminergic, angiotensin ...
M. Worcel, J. C. Gaignault
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β-Blocking Agents with Vasodilating Action
Journal of Cardiovascular Pharmacology, 1992beta-Adrenoceptor-blocking drugs in current use can be separated into two main groups: those nonselective and those selective for beta 1-receptors. Members of each group reduce cardiac output and lead to an increase in peripheral resistance with a concomitant reduction in blood flow.
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Beta-blocking agents with vasodilator activity
Journal of Hypertension, 1993Use of non-selective beta-blockers: Non-selective beta-blockers reduce blood pressure by reducing cardiac output. They have a proven record of efficacy, alone or in combination with other drug classes, in the treatment of hypertension, ischemic heart disease and some tachyarrhythmias.
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