Abstract Over the past three decades, there has been a steady increase in clinical attention to ischaemic heart failure caused by coronary microembolization. Nonetheless, a suitable mouse model for studying this condition remains limited. In the present study, we developed a mouse model of coronary microembolization‐induced ischaemic heart failure by ...
Lang Pei +10 more
wiley +1 more source
Coronary artery spasm: mechanisms, risk factors, and translational strategies for precision management. [PDF]
Kuang Z +7 more
europepmc +1 more source
Cardiac stalling: Modelling energy balance in aortic stenosis and its role in syncope
The Journal of Physiology, EarlyView.
DeWayne Townsend
wiley +1 more source
Abstract Human populations native to high altitude have evolved distinct physiological adaptations to chronic hypoxia. This adaptation is evident in the O2 transport cascade. In this review, with brief inclusion of the related genetic adaptations, we compare the O2 cascade across three well‐characterized high‐altitude populations: Andeans (Aymara and ...
Ayechew A. Getu +5 more
wiley +1 more source
Noradrenergic Slow Vasomotion: The Hidden Fluid Pump Linking Sleep, Brain Clearance, and Dementia Pathogenesis. [PDF]
Dabija MG +6 more
europepmc +1 more source
Ageing attenuates regional vasoconstriction during acute lowering of upper and lower limbs
Abstract The venoarteriolar and myogenic response (VMR) is a non‐adrenergic, non‐baroreflex‐mediated mechanism that increases local vascular resistance and contributes to blood pressure (BP) regulation during orthostasis. Despite the importance of the VMR in human cardiovascular control, no information exists elucidating possible differences in the VMR
John D. Akins +10 more
wiley +1 more source
Abstract Acute myocardial infarction is a leading cause of morbidity and mortality, with ischaemia–reperfusion (I/R) injury exacerbating myocardial damage. Vagus nerve stimulation (VNS) has been reported to exert cardioprotective effects, but its efficacy in preconditioning against I/R injury requires further investigation.
Feng Hu +10 more
wiley +1 more source
The effect of increased core body temperature on the vasomotor and sudomotor responses of patients with type 2 diabetes: protocol of a systematic literature review and meta-analysis. [PDF]
Gkiata P +3 more
europepmc +1 more source
Ouabain‐induced hypertension in rats: Mechanisms, variability and translational implications
Abstract Ouabain‐induced hypertension is a multifactorial and condition‐dependent phenomenon involving coordinated actions across vascular, renal and central nervous system pathways. At the vascular level, ouabain inhibits Na⁺/K⁺‐ATPase, particularly the α2‐isoform, leading to elevated intracellular Ca2⁺, enhanced vasoconstriction and structural ...
Priscilla Rodrigues O. Feijó +1 more
wiley +1 more source
Traditional Asian Mind-Body Exercises for Vasomotor Symptoms and Other Menopausal Symptoms in Women Experiencing Peri- and Post-Menopause: A Scoping Review Protocol. [PDF]
Tu W +3 more
europepmc +1 more source

