Results 1 to 10 of about 2,655 (189)

Impact of Pre-Heart Transplant Levosimendan Administration on Post-Transplant Vasoplegia and Primary Graft Dysfunction. [PDF]

Clin Transplant
ABSTRACT Introduction Levosimendan, a calcium‐sensitizing inotropic agent, is used in patients with advanced heart failure (HF) awaiting heart transplantation (HT). Its prolonged effects, due to an active metabolite, may influence post‐transplant vasodilation, particularly when administered shortly before HT.
Guzman-Bofarull J, Martín-Centellas A, Couto-Mallon D, Borràs R, Arenas-Loriente A, Rivas-Lasarte M, Segovia-Cubero J, Crespo-Leiro MG, García-Álvarez A, Farrero M.   +9 more
europepmc   +4 more sources

Venoarterial Extracorporeal Life Support in Circulatory Shock Secondary to Severe Vasoplegia from Ramipril Overdose [PDF]

Annals of Cardiac Anaesthesia
Management of angiotensin-converting enzyme inhibitors (ACEIs) overdose is historically challenging. We present the case of an overdose which was successfully managed with the utilization of venoarterial extracorporeal life support.
Johan van Nispen, Gabrielle Bradley, Mindaugas Rackauskas, Shiv B. Rawal, William Mulvoy, Marc O. Maybauer   +5 more
doaj   +3 more sources

Endothelial Damage in Sepsis: The Interplay of Coagulopathy, Capillary Leak, and Vasoplegia—A Physiopathological Study [PDF]

Clinics and Practice
Background: Sepsis remains a leading cause of mortality worldwide, and understanding endothelial damage is crucial for improving patient outcomes. Endothelial dysfunction in sepsis contributes to coagulopathy, increased capillary permeability, and ...
Gianni Turcato, Arian Zaboli, Lucia Filippi, Alessandro Cipriano, Paolo Ferretto, Michael Maggi, Fabrizio Lucente, Massimo Marchetti, Lorenzo Ghiadoni, Christian J. Wiedermann   +9 more
doaj   +4 more sources

Vasoplegia after implantation of a continuous flow left ventricular assist device: incidence, outcomes and predictors [PDF]

BMC Anesthesiology, 2018
Background Vasoplegia after routine cardiac surgery is associated with severe postoperative complications and increased mortality. It is also prevalent in patients undergoing implantation of pulsatile flow left ventricular assist devices (LVAD). However,
Eric E. C. de Waal, Bas van Zaane, Marnix M. van der Schoot, Albert Huisman, Faiz Ramjankhan, Wilton A. van Klei, Nandor Marczin   +6 more
doaj   +2 more sources

Successful use of methylene blue for severe vasoplegia in a patient with partially-treated portopulmonary hypertension with atrial septal defect undergoing liver transplantation: a case report [PDF]

BMC Anesthesiology
Background Vasoplegia is a life-threatening intraoperative condition. Methylene blue (MB), a potent inhibitor of nitric oxide (NO) synthase and soluble guanylyl cyclase (sGC), can treat vasoplegia but may antagonize pulmonary arterial hypertension (PAH ...
Taiga Ishihara, Gaku Kawamura, Mayuko Nagano, Seiichi Azuma, Kanji Uchida, Taro Kariya   +5 more
doaj   +2 more sources

Prolonged Postoperative Vasoplegia in Pediatric Patients on Chronic Angiotensin II Blocker Treatment [PDF]

Frontiers in Cardiovascular Medicine, 2018
Prolonged postoperative vasoplegia is known to occur following cardiac surgery in patients on chronic angiotensin II receptor blocker (ARB) treatment in adults. The perioperative management of these drugs in the pediatric population is not well described
Nischal R. Pandya, Nischal R. Pandya, Nelson Alphonso, Nelson Alphonso, Quyen Tu, Quyen Tu, Prem Venugopal, Prem Venugopal, Luregn J. Schlapbach, Luregn J. Schlapbach, Luregn J. Schlapbach   +10 more
doaj   +2 more sources

Vitamin B12 (hydroxocobalamin) administration in the management of persistent vasoplegic shock [PDF]

Saudi Journal of Anaesthesia
Vasoplegia, characterized by low systemic vascular resistance despite normal to high cardiac output, can result from various conditions, including cardiac surgery, and progress to vasoplegic shock if untreated.
Jibran Ikram, Cassandra L. Williams, Aariya Srinivasan, Jose L. Diz Ferre, Sabry Ayad   +4 more
doaj   +2 more sources

Ascorbic acid and microcirculation in cardiothoracic surgery: a pilot feasibility trial and matched cohort study [PDF]

Journal of Cardiothoracic Surgery
Background Ascorbic acid is an essential cofactor of catecholamine synthesis that increases capillary bed density and improves microcirculation perfusion.
Patrick M. Wieruszewski, Misty A. Radosevich, Scott D. Nei, Kianoush B. Kashani, Sarah E. Normand, Hartzell V. Schaff, Erica D. Wittwer   +6 more
doaj   +2 more sources

Heart Failure Impacts Endothelial Cell Responses to Cardiac Surgery on Cardiopulmonary Bypass [PDF]

Cells
Patients with heart failure with a reduced ejection fraction (HFrEF) are at an increased risk of developing postoperative hemodynamic instability and vasoplegia after surgery on cardiopulmonary bypass (CPB). Potentially pre-existing endothelial cell (EC)
Olga Papazisi, Rudmer J. Postma, Richard J. Dirven, Saskia L. M. A. Beeres, Remco R. Berendsen, Sesmu M. Arbous, Robert J. M. Klautz, Marieke E. van Vessem, Roel Bijkerk, Jan H. N. Lindeman, Meindert Palmen, Anton Jan van Zonneveld   +11 more
doaj   +2 more sources

Hydroxocobalamin for the treatment of vasoplegia after lung transplantation: A case series [PDF]

JHLT Open
Background: The use of hydroxocobalamin following lung transplantation has not been previously reported. We present a series of 3 cases where hydroxocobalamin was used to treat postoperative vasoplegia.
Anh Nguyen, MD, PhD, Rima Bouajram, PharmD, Marek Brzezinski, MD, Sahand Hassanipour, David Gordon, Binh Trinh, MD, Tobias Deuse, MD, Aida Venado, MD, Steve Hays, MD, Jonathan Singer, MD, Jasleen Kukreja, MD, MPH   +10 more
doaj   +2 more sources