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Science Translational Medicine, 2019 In the VANILLA phase 2 clinical trial, balovaptan treatment resulted in improved adaptive behaviors in adult men with autism. Modulating vasopressin in ASD The neuropeptide vasopressin has been implicated in the regulation of social behaviors in animals ...
Federico Bolognani +2 more
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Seminars in Respiratory and Critical Care Medicine, 2004
Vasopressin is a hormone that is essential for both osmotic and cardiovascular homeostasis. A deficiency of vasopressin exists in some shock states and replacement of physiological levels of vasopressin can restore vascular tone. Vasopressin is therefore emerging as a rational therapy for vasodilatory shock.
Cheryl L, Holmes, James A, Russell
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Vasopressin is a hormone that is essential for both osmotic and cardiovascular homeostasis. A deficiency of vasopressin exists in some shock states and replacement of physiological levels of vasopressin can restore vascular tone. Vasopressin is therefore emerging as a rational therapy for vasodilatory shock.
Cheryl L, Holmes, James A, Russell
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Effect of exogenous vasopressin on vasopressin release
American Journal of Physiology-Endocrinology and Metabolism, 1984To characterize the influence of extracellular volume status on vasopressin pharmacokinetics, eleven young (aged 19-31 yr) and four old (aged 62-80 yr) subjects received bolus injections of 1 mU/kg Pitressin or synthetic arginine vasopressin following 6 days of sodium depletion (10 meq Na/day) or sodium loading (250 meq Na/day).
G. L. Robertson +3 more
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Vasopressin: physiology, assessment and osmosensation
Journal of Internal Medicine, 2017 Lise Bankir +3 more
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Oxytocin, vasopressin, and human social behavior
Frontiers in Neuroendocrinology, 2009 Bernadette von Dawans, Gregor Domes
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Mice Genetically Deficient in Vasopressin V1a and V1b Receptors Are Resistant to Jet Lag
Science, 2013Yoshiaki Yamaguchi +2 more
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Vasopressin and vasopressin receptors in brain edema
2020Vasopressin is a peptide hormone produced in the hypothalamus and released from the posterior pituitary. Secretion of vasopressin is followed by activation of its receptors V1a, V1b, and V2 throughout the body. Each receptor type is responsible for a specific function of vasopressin.
J Paul Elliott +2 more
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Journal of Cardiovascular Pharmacology, 1986
The nonapeptide vasopressin is synthetized as part of a longer common precursor polypeptide, together with its carrier protein neurophysin and a glycopeptide of unknown function. The gene for this common precursor has been isolated and sequenced and shown to comprise three exons encoding, respectively, the protein domains approximately corresponding to
Dietmar Richter +2 more
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The nonapeptide vasopressin is synthetized as part of a longer common precursor polypeptide, together with its carrier protein neurophysin and a glycopeptide of unknown function. The gene for this common precursor has been isolated and sequenced and shown to comprise three exons encoding, respectively, the protein domains approximately corresponding to
Dietmar Richter +2 more
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Vasopressin and Vasopressin Antagonists in Heart Failure
2017Despite the introduction of multiple new pharmacological agents over the past three decades in the field of heart failure (HF), overall prognosis remains poor. Hyponatremia is prevalent in HF patients and has been suggested as a contributor to poor response to standard therapy.
Finn Gustafsson +1 more
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Cellular and Molecular Life Sciences, 2006
Effects of vasopressin via V1a- and V2-receptors are closely implicated in a variety of water-retaining diseases and cardiovascular diseases, including heart failure, hyponatraemia, hypertension, renal diseases, syndrome of inappropriate antidiuretic hormone secretion, cirrhosis and ocular hypertension.
Lemmens, Rosa, Kamyar, Majid-Reza
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Effects of vasopressin via V1a- and V2-receptors are closely implicated in a variety of water-retaining diseases and cardiovascular diseases, including heart failure, hyponatraemia, hypertension, renal diseases, syndrome of inappropriate antidiuretic hormone secretion, cirrhosis and ocular hypertension.
Lemmens, Rosa, Kamyar, Majid-Reza
openaire +2 more sources