Extending Cofactor‐Tethered Nanomachines to Complex Multienzyme Redox Cascades in Continuous Flow
Engineered enzyme fusions bearing covalently tethered PEG–nicotinamide cofactors enable intramolecular cofactor retention and recycling within self‐sufficient biocatalytic nanomachines. These nanomachines support cofactor‐autonomous operation of complex redox multienzyme cascades under continuous‐flow conditions, as demonstrated in a 10‐step glucose‐to‐
Zinnia Dsouza +4 more
wiley +1 more source
A comparative analysis of the impact of three distinct laparoscopic myomectomy techniques on ovarian reserve: a randomized clinical trial. [PDF]
Hashemi M +2 more
europepmc +1 more source
Influence of Carbon Nanoparticles on Electrically Induced Wear of Grease‐Lubricated Steels
When an electric current enters a pair of rubbing surfaces, enormous damage takes place. In this research, how such damage occurs in the presence of protective grease and the mitigation with added carbon nanoparticles, were investigated. It was discovered that those particles regulate transport and interfacial electrical stability of the grease ...
Mohammad Humaun Kabir +6 more
wiley +1 more source
Hormonal response following hemorrhage after severe trauma: an observational prospective study. [PDF]
Werner M +9 more
europepmc +1 more source
An adhesive hydrogel depot with polyphenol‐armored nanogenes is developed for treating aged osteoarthritis. This system maintains miR‐140 bioactivity, prolongs its intra‐articular retention, and enhances transfection into chondrocytes, leading to the downregulation of senescence‐associated pathways.
Liwei Yan +10 more
wiley +1 more source
Cellular mechanisms of long-term osmoregulation in magnocellular neurons. [PDF]
Haan KD, Fisher TE.
europepmc +1 more source
This work first time reports an eco‐friendly desert plant food‐based polysaccharide ASKP microgels which have intestinal site‐specific release properties which can achieve small‐intestine or colon targeting capability via different cross‐linking chemistry.
Huiling Yan +10 more
wiley +1 more source
The Effect of Vasopressin on 90-Day Mortality in Patients With Cardiogenic Shock: A Retrospective Cohort Study Using Propensity Score-Weighted Analysis. [PDF]
Beyls C +10 more
europepmc +1 more source
A non‐canonical core transcriptional regulatory circuit, composed of ID3, SMAD3, and NR2F2, drives Osimertinib resistance in non‐small cell lung cancer through super‐enhancer‐mediated activation of EPAS1, which couples neuroendocrine differentiation with ferroptosis evasion.
Aochu Liu +15 more
wiley +1 more source
Intramuscular vasopressin: A feasible intervention for prehospital hemodynamic stabilization in porcine hemorrhagic shock and whole blood transfusion. [PDF]
Renberg M +5 more
europepmc +1 more source

