Results 191 to 200 of about 2,482 (262)

Chronic Central Adrenal Insufficiency in a Patient With Remote Traumatic Brain Injury and an Apparently Adequate Standard‐Dose ACTH Response: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT In patients with a remote history of traumatic brain injury, central adrenal insufficiency may remain unrecognized for decades. An apparently adequate response to standard‐dose ACTH stimulation should not preclude further evaluation of the hypothalamic–pituitary–adrenal axis when clinical and biochemical findings continue to suggest adrenal ...
Kazunori Kageyama, Keisuke Sato, Satoshi Yamagata, Mizuki Tasso, Yuki Nakada, Shojiro Sawada   +5 more
wiley   +1 more source

Desmopressin dosing in children using real-world data and pharmacokinetic/pharmacodynamic model simulations. [PDF]

Pediatr Res
Yen K, Hughes E, Savic R, Srinivasan S.
europepmc   +1 more source

Pediatric Pheochromocytoma With Rapid Cyclic Blood Pressure Fluctuations: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Cyclic blood pressure fluctuations in pheochromocytoma are extremely rare, and previously reported cases have been limited to adults. We report a 5‐year‐old boy with von Hippel–Lindau disease and a left adrenal pheochromocytoma who developed rapid cyclic blood pressure fluctuations immediately after tracheal intubation.
Katsuaki Yamazaki, Chika Maeda, Kaori Morikawa, Naomi Okamoto   +3 more
wiley   +1 more source

Ethylene Glycol Poisoning Without Fomepizole in a Regional Australian Intensive Care Unit: The Lactate Gap as the Diagnostic Key and the Consequences of Nasogastric Ethanol Therapy

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT A 62‐year‐old man presented comatose with pH 6.88 and no ingestion history. A point‐of‐care lactate above 31 mmol/L with a laboratory lactate of 0.8 mmol/L revealed a lactate gap, diagnosing ethylene glycol poisoning despite a near‐normal osmolar gap. High‐dose continuous renal replacement therapy corrected the acidosis; he survived.
Jacob Athans, Prashant Maan
wiley   +1 more source

Comparison of vasopressin to epinephrine during pediatric in-hospital cardiac arrest: survival and physiologic responsiveness. [PDF]

Pediatr Res
Loaec M, Keim G, Graham K, Kienzle MF, O'Halloran A, Shepard LN, Mehta S, Sawhney S, Donoghue M, Cooper K, Kilbaugh TJ, Nadkarni V, Topjian AA, Berg RA, Sutton RM, Morgan RW.   +15 more
europepmc   +1 more source

Acute Hemorrhagic Manifestations in a Pregnant Patient With Type 1 von Willebrand Disease: Challenges in Management of Bleeding Disorders During Gestation

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT This case reports a primigravida with Type 1 von Willebrand disease experiencing hematuria and gingival bleeding despite prophylaxis. Although pregnancy raises factor levels, her response was insufficient. Desmopressin successfully controlled mucosal hemorrhage, avoiding antifibrinolytics due to obstructive risk.
Jose Luis Rojas‐Oviedo, María Fernanda Leal Walteros, Dauris Lineth Mejía Pérez, Jorge Eliecer Castellanos Corredor, Danna Geraldinne Amaya Sánchez, Ana Sofía Lancheros Ramírez   +5 more
wiley   +1 more source

Hyponatremia after pediatric surgery: Randomized trial of fluid composition on antidiuretic hormone response. [PDF]

Pediatr Res
Yokota K, Uchida H, Manaka K, Nangaku M, Kuwatsuka Y, Ando M, Nishiwaki K, Hirai T, Tainaka T, Shirota C, Sumida W, Makita S, Amano H, Hinoki A.   +13 more
europepmc   +1 more source

Lung‐Cardiovascular Interactions and Derangements in ARDS

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
This review proposes an anatomical near‐ and far‐field framework for lung‐cardiovascular interactions in ARDS. Grounded in pathological and biological studies, the evidence spans pulmonary vascular, right ventricular, and systemic endothelial derangements and reviews available evidence for targeted therapies.
Pablo A. Sanchez, Connor O'Brien, Matthieu Legrand, Carolyn S. Calfee, Michael A. Matthay   +4 more
wiley   +1 more source

Heart failure-induced reprogramming of salt-evoked neurovascular coupling in the rat hypothalamus. [PDF]

J Physiol
Roy RK, Lira EC, Ongolo MB, Filosa JA, Stern JE.   +4 more
europepmc   +1 more source

Exploiting Biocatalysis for the Scalable Synthesis of Enantiopure γ‐Hydroxynitrile Building Blocks

European Journal of Organic Chemistry, Volume 29, Issue 37, 1 October 2026.
Screening a panel of (S)‐and (R)‐selective alcohol dehydrogenases identified several biocatalysts for stereoselectively reducing γ‐ketonitriles into γ‐hydroxynitriles. These processes were optimized, delivering the targets in yields up to 88% with e.e.’s up to 99%. Scalability of the methodology was achieved to produce gram quantities of product, which
Benjamin Baumert, Kathryn Yeow, Roi Boris Tchuemmogne Tchuente, Adam Cruise, Christopher Thomas, Thomas Bayer, Uwe T. Bornscheuer, Marcus Baumann   +7 more
wiley   +1 more source