Results 31 to 40 of about 292 (87)

Beyond Vasospasm: Dual Milrinone and Balloon Angioplasty in Refractory Delayed Cerebral Ischemia Post‐Subarachnoid Hemorrhage

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Cerebral vasospasm is a major complication of aneurysmal subarachnoid hemorrhage and a key contributor to delayed cerebral ischemia, which remains a leading cause of morbidity despite standard therapy with nimodipine and induced hypertension.
Paul Cardozo Gil, Willy Pozo Soto, Alejandro Sengoku Cadima, Pablo Flores, Jorge Botello Marin, Gustavo Averanga, Richy Hurtado Montaño, Nelson Montalvo Flores   +7 more
wiley   +1 more source

Updates on aneurysmal subarachnoid hemorrhage: is there anything really new?

Arquivos de Neuro-Psiquiatria, 2022
Background: Aneurysmal subarachnoid hemorrhage (aSAH) is a severe disease, with systemic involvement and complex diagnosis and treatment. Since the current guidelines were published by the AHA/ASA, Neurocritical Care Society and the European Stroke ...
Thire Baggio Machado Marazzi, Pedro Vitale Mendes   +1 more
doaj   +1 more source

Cardiovascular Health in Women—Across the Lifespan

Clinical Endocrinology, Volume 104, Issue 6, Page 539-555, June 2026.
ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar, Jessica Yao, Simone Gong, Madhuka Wijayarathne, Monique Watts, Swati Mukherjee   +5 more
wiley   +1 more source

FGF23 and Immune Cell Signatures Causally Linked to Subarachnoid Hemorrhage: Evidence From Multi‐Omics and Genetic Colocalization

Brain and Behavior, Volume 16, Issue 5, May 2026.
Causal links identified between five inflammatory proteins, 22 immune cell types, and subarachnoid hemorrhage (SAH) via Mendelian randomization. Multi‐omics integration (pQTL, eQTL) revealed regulatory mechanisms underlying inflammation in SAH. FGF23 and CD4 Tregs emerged as key therapeutic targets, supported by colocalization and replication analysis.
Xingjie Shi, Cheng Zhang, Tao Yang, Zhiming Sun, Chao Wang, Lucheng Zhou, Shiqiang Hou, Ning Lin, Lanlan Zhang   +8 more
wiley   +1 more source

Hypotension and Bradycardia Following Papaverine Installation During Intracranial Aneurysm Surgery: A Report of Three Cases

Brazilian Neurosurgery
Introduction One of the major complications of intracranial aneurysm surgery is vasospasm. Papaverine is an effective vasodilator that can be instilled directly onto the vessels in the operative field with the aim of preventing intraoperative ...
Zahraa F. Al-Sharshahi, Samer S. Hoz, Mustafa E. Almurayati, Teeba M. Ghanim, Zahraa M. Kareem, Zahraa A. Alsubaihawi   +5 more
doaj   +1 more source

Reversible cerebral vasoconstriction syndrome: A narrative review

Headache: The Journal of Head and Face Pain, Volume 66, Issue 5, Page 1162-1180, May 2026.
Abstract Objectives/Background This review summarizes current insights into Reversible cerebral vasoconstriction syndrome (RCVS) diagnosis, management, and outcomes. RCVS is a cerebrovascular disorder characterized by recurrent thunderclap headaches and transient segmental vasoconstriction of cerebral arteries, typically resolving within 3 months ...
Ícaro Araújo de Sousa, Abner da Silva Machado, Arthur de Oliveira Veras, Thiago Oscar Goulart, Sarah Galassi Tatsuta, Trajano Aguiar Pires Gonçalves, Eva Rocha, Octávio Marques Pontes‐Neto   +7 more
wiley   +1 more source

DNA Methylation‐Regulated ZDHHC24 Exacerbates the Risk of Intracranial Aneurysms

Brain and Behavior, Volume 16, Issue 4, April 2026.
Multimodal Mendelian randomization integrating multi‐omics datasets pinpointed four DNA‐methylation loci that act in concert with the palmitoylation gene ZDHHC24 to modulate intracranial aneurysm risk, shedding new light on the molecular etiology of IA susceptibility and highlighting potential therapeutic targets.
Hao Yuan, Can Li, Xin Feng, Jiancheng Lin, Chi Huang, Mengshi Huang, Chuanzhi Duan   +6 more
wiley   +1 more source

Pathological Roles of Astrocytes in Traumatic Brain Injury

CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
TBI induces intrinsic astrocytic changes, including reactive astrogliosis, A1 and A2 polarization, ion channels activation, pathological edema, oxidative stress, and metabolic dysregulation. These injury‐responsive astrocytes regulate neuroinflammation and tissue remodeling through dynamic crosstalk with microglia, macrophages, vascular endothelial ...
Di Wu, Yuxiao Ma, Baofeng Wang, Yongtao Zheng, Jie Ren, Qingfang Sun, Liuguan Bian, Yuhao Sun   +7 more
wiley   +1 more source

Vasospasm and delayed cerebral ischemia after uneventful clipping of an unruptured intracranial aneurysm – a case report

BMC Neurology, 2019
Background Due to improvements in both the quality and availability of intracranial imaging as well as the evolution of surgical and endovascular techniques during the last decade, the number of treatments of unruptured intracranial aneurysms (UIA) has ...
Christin Campe, Jens Neumann, I. Erol Sandalcioglu, Ali Rashidi, Michael Luchtmann   +4 more
doaj   +1 more source

Feasibility and Outcomes of Clazosentan in Ruptured Vertebrobasilar Dissecting Aneurysms: A Retrospective Cohort Study

Health Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background and Aims Subarachnoid hemorrhage (SAH) caused by ruptured vertebrobasilar dissecting aneurysms (VBDAs) is associated with high morbidity and mortality rates. Although clazosentan is effective in preventing cerebral vasospasm after SAH due to saccular aneurysms, its efficacy and safety have not yet been established in patients with ...
Takuma Maeda, Tatsuki Kimura, Hiroki Kobayashi, Akio Teranishi, Yushiro Take, Tomomichi Kayahara, Kaima Suzuki, Masataka Yoshimura, Shinya Kohyama, Hiroki Kurita   +9 more
wiley   +1 more source