Results 31 to 40 of about 12,367 (135)
Abstract Advanced age is the strongest risk factor for Alzheimer's disease and related dementias (ADRDs). Traumatic brain injury (TBI) has also been recognized as a risk factor for ADRD, potentially contributing to an earlier onset of the disease. Thus, elucidating the mechanisms underlying brain ageing and TBI is critical for developing strategies to ...
Tsubasa Tomoto +3 more
wiley +1 more source
The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp +4 more
wiley +1 more source
Outcome of intracranial aneurysm surgery: single center experience
Purpose: Intracranial aneurysms are the most common reason of the subarachnoid hemorrhages and cause significant rate of morbidity and mortality. In this article, we aimed to share the results of our intracranial aneurysm surgery.
Murat Ulutas
doaj +1 more source
Updates on aneurysmal subarachnoid hemorrhage: is there anything really new?
Background: Aneurysmal subarachnoid hemorrhage (aSAH) is a severe disease, with systemic involvement and complex diagnosis and treatment. Since the current guidelines were published by the AHA/ASA, Neurocritical Care Society and the European Stroke ...
Thire Baggio Machado Marazzi +1 more
doaj +1 more source
ABSTRACT In severe bacterial meningitis, an initially non‐critical or technically unreliable lumbar puncture opening pressure should not reassure when hydrocephalus and coma persist. Bedside transcranial Doppler cannot measure intracranial pressure, but bilateral near‐absent diastolic flow may provide an urgent warning signal prompting repeat ...
Mahmoud Ahmed +2 more
wiley +1 more source
Introduction One of the major complications of intracranial aneurysm surgery is vasospasm. Papaverine is an effective vasodilator that can be instilled directly onto the vessels in the operative field with the aim of preventing intraoperative ...
Zahraa F. Al-Sharshahi +5 more
doaj +1 more source
ABSTRACT Background Glutamate is the main excitatory neurotransmitter in the brain, and extracellular levels of glutamate and glycerol (a breakdown product of cell damage) increase after severe acute brain injury. Previous studies report that increased intracerebral glutamate—measured using cerebral microdialysis (CMD)—is associated with unfavorable ...
Trine Hjorslev Andreasen +7 more
wiley +1 more source
ABSTRACT Objective This analysis evaluates the effect of successful reperfusion on functional outcomes after MT, stratified by admission National Institutes of Health Stroke Scale (NIHSS) and Alberta Stroke Program Early CT Score (ASPECTS) as surrogates for clinical‐core mismatch, using multicenter registry data.
Felix Schlicht +53 more
wiley +1 more source
Background Due to improvements in both the quality and availability of intracranial imaging as well as the evolution of surgical and endovascular techniques during the last decade, the number of treatments of unruptured intracranial aneurysms (UIA) has ...
Christin Campe +4 more
doaj +1 more source
ABSTRACT Neurological deterioration, headache, vomiting, bradycardia, or hypertension after emergent percutaneous coronary intervention should prompt immediate brain imaging. When subarachnoid hemorrhage is detected shortly after coronary stenting, the hemorrhage onset may remain uncertain, and antiplatelet decisions require individualized ...
Chul Hee Lee
wiley +1 more source

